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Pediatric Drug Research: Studies Conducted under Best Pharmaceuticals for Children Act (open access)

Pediatric Drug Research: Studies Conducted under Best Pharmaceuticals for Children Act

A letter report issued by the Government Accountability Office with an abstract that begins "About two-thirds of drugs that are prescribed for children have not been studied and labeled for pediatric use, which places children at risk of being exposed to ineffective treatment or incorrect dosing. The Best Pharmaceuticals for Children Act (BPCA), enacted in 2002, encourages the manufacturers, or sponsors, of drugs that still have marketing exclusivity--that is, are on-patent--to conduct pediatric drug studies, as requested by the Food and Drug Administration (FDA). If they do so, FDA may extend for 6 months the period during which no equivalent generic drugs can be marketed. This is referred to as pediatric exclusivity. BPCA required that GAO assess the effect of BPCA on pediatric drug studies and labeling. As discussed with the committees of jurisdiction, GAO (1) assessed the extent to which pediatric drug studies were being conducted under BPCA for on-patent drugs, including when drug sponsors declined to conduct the studies; (2) evaluated the impact of BPCA on labeling drugs for pediatric use and the process by which the labeling was changed; and (3) illustrated the range of diseases treated by the drugs studied under BPCA. GAO examined data about …
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Social Security Reform: Greater Transparency Needed about Potential General Revenue Financing (open access)

Social Security Reform: Greater Transparency Needed about Potential General Revenue Financing

A letter report issued by the Government Accountability Office with an abstract that begins "Absent reform, Social Security's financing gap will grow until currently scheduled benefits can no longer be paid in full. Recent reform proposals often include general revenue (GR)--a major change that can have significant implications for the budget as a whole. This report addresses these issues: (1) What information is available about GR in recent proposal scorings by Social Security's Office of the Chief Actuary (OCACT)? (2) What common mechanisms, especially GR mechanisms, are used to increase program revenue? (3) What are the implications of GR for the trust fund and the federal budget? We have prepared this report under the Comptroller General's statutory authority to conduct evaluations on his own initiative as part of a continued effort to assist Congress in addressing the challenges facing Social Security."
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Federal Aviation Administration: Key Issues in Ensuring the Efficient Development and Safe Operation of the Next Generation Air Transportation System (open access)

Federal Aviation Administration: Key Issues in Ensuring the Efficient Development and Safe Operation of the Next Generation Air Transportation System

Testimony issued by the Government Accountability Office with an abstract that begins "The Federal Aviation Administration (FAA) operates one of the safest air transportation systems in the world. It is, however, a system under strain. The skies are becoming more crowded every day, with an estimated 1 billion passengers per year expected by 2015. The current aviation system cannot be expanded to meet this growth. The reauthorization of FAA is an opportunity to examine how the agency is managing the operation and safety of the air transportation system as it leads the transition to the Next Generation Air Transportation System (NextGen)--a major redesign of the current system. GAO's testimony focuses on key issues related to FAA's reauthorization, including (1) FAA's progress in implementing initiatives that could provide a solid foundation for NextGen, (2) issues that need to be addressed to help ensure a successful transition to NextGen, and (3) safety areas that are important for the continued safe operation of the current and future system. This statement is based on recent GAO reports and ongoing work on some management and safety initiatives."
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Operation Iraqi Freedom: DOD Should Apply Lessons Learned Concerning the Need for Security over Conventional Munitions Storage Sites to Future Operations Planning (open access)

Operation Iraqi Freedom: DOD Should Apply Lessons Learned Concerning the Need for Security over Conventional Munitions Storage Sites to Future Operations Planning

A letter report issued by the Government Accountability Office with an abstract that begins "Following the invasion of Iraq in March 2003--known as Operation Iraqi Freedom (OIF)--concerns were raised about how the Department of Defense (DOD) secured Iraqi conventional munitions storage sites during and after major combat operations. Because of the broad interest in this issue, GAO conducted this work under the Comptroller General's authority to conduct evaluations. This report examines (1) the security provided by U.S. forces over Iraqi conventional munitions storage sites and (2) DOD actions to mitigate risks associated with an adversary's conventional munitions storage sites for future operations on the basis of OIF lessons learned. To address these objectives, GAO reviewed OIF war plans, joint doctrine and policy, and intelligence reports, and interviewed senior-level DOD officials."
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Next Generation Air Transportation System: Progress and Challenges in Planning and Implementing the Transformation of the National Airspace System (open access)

Next Generation Air Transportation System: Progress and Challenges in Planning and Implementing the Transformation of the National Airspace System

Testimony issued by the Government Accountability Office with an abstract that begins "The skies over America are becoming more crowded every day. The consensus of opinion is that the current aviation system cannot be expanded to meet this projected growth. Recognizing the need for system transformation, in 2003 Congress authorized the Joint Planning and Development Office (JPDO) and requires the office to operate in conjunction with multiple federal agencies, including the Departments of Transportation, Commerce, Defense, and Homeland Security; the Federal Aviation Administration (FAA); the National Aeronautics and Space Administration (NASA); and the White House Office of Science and Technology Policy. JPDO is responsible for coordinating the related efforts of these partner agencies to plan the transformation to the Next Generation Air Transportation System (NextGen): a fundamental redesign of the national airspace system. FAA will be largely responsible for implementing the policies and systems necessary for NextGen, while safely operating the current air traffic control system. GAO's testimony focuses on (1) the progress that JPDO has made in planning NextGen and some challenges it continues to face and (2) the challenges that FAA faces transitioning to NextGen. GAO's statement is based on our recent reports as well as ongoing work, …
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Operation Iraqi Freedom: DOD Should Apply Lessons Learned Concerning the Need for Security over Conventional Munitions Storage Sites to Future Operations Planning (open access)

Operation Iraqi Freedom: DOD Should Apply Lessons Learned Concerning the Need for Security over Conventional Munitions Storage Sites to Future Operations Planning

Testimony issued by the Government Accountability Office with an abstract that begins "GAO is releasing a report today on lessons learned concerning the need for security over conventional munitions storage sites which provides the basis for this testimony. Following the invasion of Iraq in March 2003--known as Operation Iraqi Freedom (OIF)--concerns were raised about how the Department of Defense (DOD) secured Iraqi conventional munitions storage sites during and after major combat operations. This testimony addresses (1) the security provided by U.S. forces over Iraqi conventional munitions storage sites and (2) DOD actions to mitigate risks associated with an adversary's conventional munitions storage sites for future operations on the basis of OIF lessons learned. To address these objectives, GAO reviewed OIF war plans, joint doctrine and policy, intelligence reports, and interviewed senior-level DOD officials."
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Defense Acquisitions: Analysis of Costs for the Joint Strike Fighter Engine Program (open access)

Defense Acquisitions: Analysis of Costs for the Joint Strike Fighter Engine Program

Testimony issued by the Government Accountability Office with an abstract that begins "The Joint Strike Fighter (JSF) is the linchpin of future Department of Defense (DOD) tactical aircraft modernization efforts because of the sheer size of the program and its envisioned role as the replacement for hundreds of aircraft that perform a wide variety of missions in the Air Force, Navy, and Marine Corps. DOD implemented the JSF alternate engine development program in 1996 to provide competition between two engine manufacturers in an effort to achieve cost savings, improve performance, and gain other benefits. This testimony focuses on GAO's cost analysis performed in response to Section 211 of the John Warner National Defense Authorization Act for Fiscal Year 2007. We examined the following areas: (1) sole-source and competitive scenarios for development, production, and sustainment of the JSF engine, (2) results of past engine programs and their related strategies, and (3) impact on the industrial base in the event of the complete cancellation of the JSF alternate engine program. DOD did not provide comments on our findings."
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Stabilizing Iraq: Preliminary Observations on Budget and Management Challenges of Iraq's Security Ministries (open access)

Stabilizing Iraq: Preliminary Observations on Budget and Management Challenges of Iraq's Security Ministries

Testimony issued by the Government Accountability Office with an abstract that begins "In November 2005, the President issued the National Strategy for Victory in Iraq. According to the strategy, victory will be achieved when Iraq is peaceful, united, stable, secure, well integrated into the international community, and a full partner in the global war on terror. To help Iraq achieve this, the U.S. is, among other efforts, helping strengthen the capabilities of the Iraq Ministries of Defense and Interior (police forces) so they can assume greater responsibility for the country's security. The United States has provided about $15.4 billion to develop Iraqi security forces and institutions. In this testimony, GAO discusses preliminary observations on (1) U.S. and Iraqi funding to develop and sustain the Iraqi security forces, and (2) key challenges the United States and Iraq face in improving the security ministries' operations and management. This statement is based on prior GAO reports, recent fieldwork in Iraq and Department of Defense, U.S. Treasury and Embassy budget documents. GAO added information to this statement in response to comments from Multinational Security Transition Command-Iraq. We completed the work in accordance with generally accepted government auditing standards."
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Greensheet (Houston, Tex.), Vol. 38, No. 80, Ed. 1 Thursday, March 22, 2007 (open access)

Greensheet (Houston, Tex.), Vol. 38, No. 80, Ed. 1 Thursday, March 22, 2007

Free weekly newspaper that includes business and classified advertising.
Date: March 22, 2007
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Greensheet (Houston, Tex.), Vol. 38, No. 81, Ed. 1 Thursday, March 22, 2007 (open access)

Greensheet (Houston, Tex.), Vol. 38, No. 81, Ed. 1 Thursday, March 22, 2007

Free weekly newspaper that includes business and classified advertising.
Date: March 22, 2007
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Texas Jewish Post (Fort Worth, Tex.), Vol. 61, No. 12, Ed. 1 Thursday, March 22, 2007 (open access)

Texas Jewish Post (Fort Worth, Tex.), Vol. 61, No. 12, Ed. 1 Thursday, March 22, 2007

Weekly Jewish newspaper from Fort Worth, Texas that includes local, state and national news along with extensive advertising.
Date: March 22, 2007
Creator: Wisch, Rene
Object Type: Newspaper
System: The Portal to Texas History
Article 98 Agreements and Sanctions on U.S. Foreign Aid to Latin America (open access)

Article 98 Agreements and Sanctions on U.S. Foreign Aid to Latin America

This report is on Article 98 Agreements and Sanctions on U.S. Foreign Aid to Latin America.
Date: March 22, 2007
Creator: Ribando, Clare M.
Object Type: Report
System: The UNT Digital Library
Port Aransas South Jetty (Port Aransas, Tex.), Vol. 37, No. 12, Ed. 1 Thursday, March 22, 2007 (open access)

Port Aransas South Jetty (Port Aransas, Tex.), Vol. 37, No. 12, Ed. 1 Thursday, March 22, 2007

Weekly newspaper from Port Aransas, Texas on Mustang Island that includes local, state and national news along with extensive advertising.
Date: March 22, 2007
Creator: Judson, Mary Henkel
Object Type: Newspaper
System: The Portal to Texas History
The Albany News (Albany, Tex.), Vol. 131, No. 42, Ed. 1 Thursday, March 22, 2007 (open access)

The Albany News (Albany, Tex.), Vol. 131, No. 42, Ed. 1 Thursday, March 22, 2007

Weekly newspaper from Albany, Texas that includes local, county, and state news along with extensive advertising.
Date: March 22, 2007
Creator: Lucas, Melinda L.
Object Type: Newspaper
System: The Portal to Texas History
The Greensheet (Arlington-Grand Prairie, Tex.), Vol. 30, No. 346, Ed. 1 Thursday, March 22, 2007 (open access)

The Greensheet (Arlington-Grand Prairie, Tex.), Vol. 30, No. 346, Ed. 1 Thursday, March 22, 2007

Free weekly newspaper that includes business and classified advertising.
Date: March 22, 2007
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Archer County News (Archer City, Tex.), No. 12, Ed. 1 Thursday, March 22, 2007 (open access)

Archer County News (Archer City, Tex.), No. 12, Ed. 1 Thursday, March 22, 2007

Weekly newspaper from Archer City, Texas that includes local, state, and national news along with advertising.
Date: March 22, 2007
Creator: Lewis, Shelley
Object Type: Newspaper
System: The Portal to Texas History
Polk County Enterprise (Livingston, Tex.), Vol. 125, No. 23, Ed. 1 Thursday, March 22, 2007 (open access)

Polk County Enterprise (Livingston, Tex.), Vol. 125, No. 23, Ed. 1 Thursday, March 22, 2007

Semi-weekly newspaper from Livingston, Texas that includes local, state and national news along with advertising.
Date: March 22, 2007
Creator: White, Barbara
Object Type: Newspaper
System: The Portal to Texas History
Comanche Chief (Comanche, Tex.), No. 47, Ed. 1 Thursday, March 22, 2007 (open access)

Comanche Chief (Comanche, Tex.), No. 47, Ed. 1 Thursday, March 22, 2007

Weekly newspaper from Comanche, Texas that includes local, state, and national news along with advertising.
Date: March 22, 2007
Creator: Wilkerson, James C., III
Object Type: Newspaper
System: The Portal to Texas History
The Odem-Edroy Times (Odem, Tex.), Vol. 61, No. 12, Ed. 1 Thursday, March 22, 2007 (open access)

The Odem-Edroy Times (Odem, Tex.), Vol. 61, No. 12, Ed. 1 Thursday, March 22, 2007

Weekly newspaper from Odem, Texas that includes local, state, and national news along with advertising.
Date: March 22, 2007
Creator: Mogonye, Kurt R.
Object Type: Newspaper
System: The Portal to Texas History
Hondo Anvil Herald (Hondo, Tex.), Vol. 121, No. 12, Ed. 1 Thursday, March 22, 2007 (open access)

Hondo Anvil Herald (Hondo, Tex.), Vol. 121, No. 12, Ed. 1 Thursday, March 22, 2007

Weekly newspaper from Hondo, Texas that includes local, state, and national news along with extensive advertising.
Date: March 22, 2007
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Drug Safety: FDA Needs to Further Address Shortcomings in Its Postmarket Decision-making Process (open access)

Drug Safety: FDA Needs to Further Address Shortcomings in Its Postmarket Decision-making Process

Testimony issued by the Government Accountability Office with an abstract that begins "GAO was asked to testify on the effectiveness of the Food and Drug Administration's (FDA) postmarket decision-making process. This testimony is based on Drug Safety: Improvement Needed in FDA's Postmarket Decision-making and Oversight Process, GAO-06-402 (March 31, 2006). The report focused on the complex interaction between two offices within FDA that are involved in postmarket drug safety activities: the Office of New Drugs (OND), and the Office of Drug Safety (ODS). OND's primary responsibility is to review new drug applications, but it is also involved in monitoring the safety of marketed drugs. ODS is focused primarily on postmarket drug safety issues. ODS is now called the Office of Surveillance and Epidemiology. For its report, GAO reviewed FDA policies, interviewed FDA staff, and conducted case studies of four drugs with safety issues: Arava, Baycol, Bextra, and Propulsid. To gather information on FDA's initiatives since March 2006 to improve its decision-making process for this testimony, GAO interviewed FDA officials and reviewed FDA documents in February and March 2007."
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
The Sachse News (Sachse, Tex.), Vol. 3, No. 8, Ed. 1 Thursday, March 22, 2007 (open access)

The Sachse News (Sachse, Tex.), Vol. 3, No. 8, Ed. 1 Thursday, March 22, 2007

Weekly newspaper from Sachse, Texas that includes local, state and national news along with advertising.
Date: March 22, 2007
Creator: Fisher, Donnita Nesbit
Object Type: Newspaper
System: The Portal to Texas History
The Baytown Sun (Baytown, Tex.), Vol. 86, No. 115, Ed. 1 Thursday, March 22, 2007 (open access)

The Baytown Sun (Baytown, Tex.), Vol. 86, No. 115, Ed. 1 Thursday, March 22, 2007

Daily newspaper from Baytown, Texas that includes local, state, and national news along with advertising.
Date: March 22, 2007
Creator: Clements, Clifford E.
Object Type: Newspaper
System: The Portal to Texas History
Stamford American (Stamford, Tex.), Vol. 85, No. 49, Ed. 1 Thursday, March 22, 2007 (open access)

Stamford American (Stamford, Tex.), Vol. 85, No. 49, Ed. 1 Thursday, March 22, 2007

Weekly newspaper from Stamford, Texas that includes local, state, and national news along with advertising.
Date: March 22, 2007
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History