Interpreting genomic data via entropic dissection (open access)

Interpreting genomic data via entropic dissection

Article on interpreting genomic data via entropic dissection.
Date: October 3, 2012
Creator: Azad, Rajeev K. & Li, Jing
Object Type: Article
System: The UNT Digital Library

Comparison of Machine Learning Algorithms for Identifying Cancer Types

Poster for the 2014 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Annual Conference. This poster discusses a comparison of machine learning algorithms for identifying cancer types.
Date: March 2014
Creator: Saxena, Garima; Helsing, Joseph; Reyes, Omar Costilla & Azad, Rajeev K.
Object Type: Poster
System: The UNT Digital Library
Detecting Evolutionary Strata on the Human X Chromosome in the Absence of Gametologous Y-Linked Sequences (open access)

Detecting Evolutionary Strata on the Human X Chromosome in the Absence of Gametologous Y-Linked Sequences

Article on detecting evolutionary strata on the human X chromosome in the absence of gametologous Y-linked sequences.
Date: September 9, 2013
Creator: Pandey, Ravi Shanker; Sayres, Melissa A. Wilson & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Generalization of Entropy Based Divergence Measures for Symbolic Sequence Analysis (open access)

Generalization of Entropy Based Divergence Measures for Symbolic Sequence Analysis

Article on the generalization of entropy based divergence measures for symbolic sequence analysis.
Date: September 17, 2013
Creator: Ré, Miguel A. & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells (open access)

Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells

This article shows that small hairpin RNA-mediated suppresion of NAF-1 results in the activation of apoptosis in epithelial breast cancer cells and xenograft tumors.
Date: November 11, 2015
Creator: Holt, Sarah H.; Darash-Yahana, Merav; Sohn, Yang Sung; Song, Luhua; Karmi, Ola; Tamir, Sagi et al.
Object Type: Article
System: The UNT Digital Library
ABA Is Required for Plant Acclimation to a Combination of Salt and Heat Stress (open access)

ABA Is Required for Plant Acclimation to a Combination of Salt and Heat Stress

This article highlights the important role abscisic acid plays in the acclimation of plants to a combination of two different abiotic stresses.
Date: January 29, 2016
Creator: Suzuki, Nobuhiro; Bassil, Elias; Hamilton, Jason S.; Inupakutika, Madhuri A.; Zandalinas, Sara I.; Tripathy, Deesha et al.
Object Type: Article
System: The UNT Digital Library
Identification of Novel Genomic Islands in Liverpool Epidemic Strain of Pseudomonas aeruginosa Using Segmentation and Clustering (open access)

Identification of Novel Genomic Islands in Liverpool Epidemic Strain of Pseudomonas aeruginosa Using Segmentation and Clustering

This article utilizes a recursive segmentation and cluster procedure presented as a genome-mining tool, GEMINI, to decipher genomic islands and understand their contributions to the evolution of virulence and antibiotic resistance in Pseudomonas aeruginosa.
Date: August 3, 2016
Creator: Jani, Mehul; Mathee, Kalal & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing (open access)

Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing

This article demonstrates that whole genome sequencing is an efficient approach for identification of causative genes underlying symbiotic nitrogen fixation defective phenotypes in Medicago truncatula Tnt1 insertion mutants obtained via forward genetic screens.
Date: February 27, 2016
Creator: Veerappan, Vijaykumar; Jani, Mehul; Kadel, Khem; Troiani, Taylor; Gale, Ronny; Mayes, Tyler et al.
Object Type: Article
System: The UNT Digital Library
Ultra-Fast Alterations in mRNA Levels Uncover Multiple Players in Light Stress Acclimation in Plants (open access)

Ultra-Fast Alterations in mRNA Levels Uncover Multiple Players in Light Stress Acclimation in Plants

This article contains RNA sequencing analysis of Arabidopsis thaliana plants subjected to light stress in order to identify and characterize rapid changes in the steady-state level of different transcripts in response to light stress.
Date: September 26, 2015
Creator: Suzuki, Nobuhiro; Devireddy, Amith R.; Inupakutika, Madhuri A.; Baxter, Aaron; Miller, Gad; Song, Luhua et al.
Object Type: Article
System: The UNT Digital Library
Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans (open access)

Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans

This article discusses how RNA-sequencing analysis was performed to assess how a glucose-supplemented diet and/or a hyl-2 mutation altered the transcriptome.
Date: August 5, 2016
Creator: Ladage, Mary L.; King, Skylar D.; Burks, David J.; Quan, Daniel L.; Garcia, Anastacia M.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Identification and Network-Enabled Characterization of Auxin Response Factor Genes in Medicago truncatula (open access)

Identification and Network-Enabled Characterization of Auxin Response Factor Genes in Medicago truncatula

This article discusses a comprehensive analysis of the Medicago truncatula genome and transcriptome that entailed search for novel Auxin Response Factor genes and the co-expression networks.
Date: December 9, 2016
Creator: Burks, David J. & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates (open access)

Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates

This article describes the use of three members of the human NEET protein family (CISD1, mitoNEET; CISD2, NAF-1 or Miner 1; and CISD3, Miner2) as guides to conduct a phylogenetic analysis of eukaryotic NEET proteins and their evolution.
Date: February 16, 2017
Creator: Inupakutika, Madhuri A.; Sengupta, Soham; Nechushtai, Rachel; Jennings, Patricia A.; Onuchic, José N.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Interactions between mitoNEET and NAF-1 in cells (open access)

Interactions between mitoNEET and NAF-1 in cells

This article uses yeast two-hybrid to demonstrate through vivo bimolecular fluorescence complementation (BiFC), direct coupling analysis (DCA), RNA-sequencing, ROS and iron imaging, and single and double shRNA lines with suppressed mNT, NAF-1 and mNT/NAF-1 expression, that mNT and NAF-1 directly interact in mammalian cells and could function in the same cellular pathway.
Date: April 20, 2017
Creator: Karmi, Ola; Holt, Sarah H.; Song, Luhua; Tamir, Sagi; Luo, Yuting; Bai, Fang et al.
Object Type: Article
System: The UNT Digital Library
Environmental vibrios represent a source of antagonistic compounds that inhibit pathogenic Vibrio cholerae and Vibrio parahaemolyticus strains (open access)

Environmental vibrios represent a source of antagonistic compounds that inhibit pathogenic Vibrio cholerae and Vibrio parahaemolyticus strains

This article predicts that marine-derived bacteria should inhibit Vibrio pathogens and may be a source of unique antibiotic compounds.
Date: March 10, 2017
Creator: Burks, David J.; Norris, Stephen; Kauffman, Kathryn M.; Joy, Abigail; Arevalo, Philip; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin (open access)

Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin

This article reports on the origin, evolution, and diversification of the iron-sulfur (2Fe-2S) binding motif CDGSH.
Date: November 28, 2017
Creator: Sengupta, Soham; Nechushtai, Rachel; Jennings, Patricia A.; Onuchic, José N.; Padilla, Pamela A.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes (open access)

Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes

This article explores the use of an information-entropy-based gene clustering method for genomic island detection in MRSA.
Date: November 16, 2017
Creator: Jani, Mehul; Sengupta, Soham; Hu, Kelsey & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Local and Systemic Metabolic Responses during Light-Induced Rapid Systemic Signaling (open access)

Local and Systemic Metabolic Responses during Light-Induced Rapid Systemic Signaling

This article reports that local application of light stress to one rosette leaf of bolting Arabidopsis (Arabidopsis thaliana) plants resulted in a metabolic response that encompassed local, systemic and transport tissues, demonstrating a high degree of physical and metabolic continuity between different tissues throughout the plant.
Date: December 2018
Creator: Choudhury, Feroza K.; Devireddy, Amith R.; Azad, Rajeev K.; Shulaev, Vladimir & Mittler, Ron
Object Type: Article
System: The UNT Digital Library
Identification and characterization of a core set of ROS wave‐associated transcripts involved in the systemic acquired acclimation response of Arabidopsis to excess light (open access)

Identification and characterization of a core set of ROS wave‐associated transcripts involved in the systemic acquired acclimation response of Arabidopsis to excess light

Article reveal that the systemic transcriptomic response of plants to excess light stress is extensive in the context of systemic acquired acclimation and involves an early (2 min) and transient stage of transcript expression that includes thousands of genes.
Date: December 6, 2018
Creator: Zandalinas, Sara I.; Sengupta, Soham; Burks, David; Azad, Rajeev K. & Mittler, Ron
Object Type: Article
System: The UNT Digital Library
IslandCafe: Compositional Anomaly and Feature Enrichment Assessment for Delineation of Genomic Islands (open access)

IslandCafe: Compositional Anomaly and Feature Enrichment Assessment for Delineation of Genomic Islands

Article discusses IslandCafe, a proposed method for genomic island detection.
Date: October 1, 2019
Creator: Jani, Mehul & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
The genome of jojoba (Simmondsia chinensis): A taxonomically isolated species that directs wax ester accumulation in its seeds (open access)

The genome of jojoba (Simmondsia chinensis): A taxonomically isolated species that directs wax ester accumulation in its seeds

Article describes the high-quality, 887-Mb genome of jojoba assembled into 26 chromosomes with 23,490 protein-coding genes.
Date: March 11, 2020
Creator: Sturtevant, Drew; Lu, Shaoping; Zhou, Zhi-Wei; Shen, Yin; Wang, Shuo; Song, Jia-Ming et al.
Object Type: Article
System: The UNT Digital Library
Traffic generated emissions alter the lung microbiota by promoting the expansion of Proteobacteria in C57Bl/6 mice placed on a high-fat diet (open access)

Traffic generated emissions alter the lung microbiota by promoting the expansion of Proteobacteria in C57Bl/6 mice placed on a high-fat diet

Article investigating exposure to traffic-generated emissions and the potential to alter lung microbiota and immune defenses. Results show that the combined effects of ME and HF diet result in decreased immune surveillance and lung bacterial dysbiosis, which is of significance in lung diseases.
Date: April 15, 2021
Creator: Daniel, Sarah; Pusadkar, Vaidehi; McDonald, Jacob D.; Mirpuri, Julie; Azad, Rajeev K.; Goven, Art et al.
Object Type: Article
System: The UNT Digital Library
Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans (open access)

Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans

This article identifies that an rRNA released in hemolysis activates clotting in human and zebrafish plasma. Furthermore, it shows that fish Hgfac plays a role in rRNA-mediated activation of coagulation.
Date: November 17, 2021
Creator: Alharbi, Abdulmajeed; Iyer, Neha; Al Qaryoute, Ayah; Raman, Revathi; Burks, David J.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Systemic signaling during abiotic stress combination in plants (open access)

Systemic signaling during abiotic stress combination in plants

Article reveals that plants can integrate different local and systemic signals generated during conditions of stress combination. Furthermore, results show that the specific part at which plants sense the two co-occurring stresses makes a significant difference in how fast and efficient they acclimate.
Date: May 29, 2020
Creator: Sengupta, Soham; Azad, Rajeev K.; Zandalinas, Sara I.; Fichman, Yosef; Devireddy, Amith R. & Mittler, Ron
Object Type: Article
System: The UNT Digital Library
Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings (open access)

Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings

Article presents a study where whole transcriptome sequencing (RNA-seq) and differential expression analysis were used to identify early (1–3 hr) transcriptional changes induced by the exogenous treatment of NAE 18:2 and NAE 18:3 in cotyledons, roots, and seedlings.
Date: July 15, 2020
Creator: Cannon, Ashley E.; Yan, Chengshi; Burks, David J.; Rao, Xiaolan; Azad, Rajeev K. & Chapman, Kent Dean
Object Type: Article
System: The UNT Digital Library