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Multifaceted Shape Memory Polymer Technology for Biomedical Application: Combining Self-Softening and Stretchability Properties
Article describes how thiol-ene polymers are a promising class of biomaterials with a wide range of potential applications, including organs-on-a-chip, microfluidics, drug delivery, and wound healing. This study investigated the incorporation of di-acrylate chain extenders to improve the stretchability and conformability of those flexible thiol-ene polymers.
Date:
October 25, 2023
Creator:
Chitrakar, Chandani; Torres, Marc Anthony; Rocha-Flores, Pedro Emanuel; Hu, Qichan & Ecker, Melanie
Object Type:
Article
System:
The UNT Digital Library
Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model
Article describes how recently, natural killer cells emerged as a treatment option for various solid tumors. The effect of activated pancreatic stellate cells on natural killer cell-mediated anticancer efficacy under three-dimensional coculture conditions was investigated.
Date:
September 27, 2023
Creator:
Kim, Hyun-Ah; Kim, Hyunsoo; Nam, Min-Kyung; Park, Jong Kook; Lee, Moo-Yeal; Chung, Seok et al.
Object Type:
Article
System:
The UNT Digital Library
Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries
Article describes how skeletal muscle regeneration relies on the tightly temporally regulated lineage progression of muscle stem/progenitor cells (MPCs) from activation to proliferation and finally, differentiation. The authors developed an engineering strategy to tune the therapeutic potential of EVs using nanotopographical cues.
Date:
October 5, 2023
Creator:
Wang, Kai; Frey, Nolan; Garcia, Andres C.; Man, Kun; Yang, Yong; Gualerzi, Alice et al.
Object Type:
Article
System:
The UNT Digital Library
Surface Nanostructures Enhanced Biocompatibility and Osteoinductivity of laser-Additively Manufactured CoCrMo Alloys
Article describes how cobalt–chromium–molybdenum (CoCrMo) alloys are widely used in orthopedic implants due to their excellent corrosion and wear resistance and superior mechanical properties. In this study, the authors prepared CoCrMo alloys with surface nanostructures of various aspect ratios (AR) using laser-directed energy deposition (L-DED) and biocorrosion.
Date:
December 6, 2023
Creator:
Man, Kun; Mazumder, Sangram; Dahotre, Narendra B. & Yang, Yong
Object Type:
Article
System:
The UNT Digital Library