This article explores the short-term effects of extracellular Zn²⁺ on human smooth muscle cells.

This review compares the advantages and disadvantages of decellularization methods in terms of their ability to retain desired extracellular matrix characteristics for particular tissues and organs.

Article introducing a special issue discussing the link between the metabolic syndrome and the development and progression of cancer. The role of inflammation in these diseases and identification of new therapeutic targets are of great significance. This special issue contributes original research papers and review articles that motivate the continuous efforts to comprehend the mechanisms, production, and management related to cancers associated with the metabolic syndrome.

This review article will focus on known risks following iron oxide nanoparticles (IONPs) exposure supported by human, animal, and cell culture-based studies, the potential challenges intrinsic to IONPs toxicity assessment, and how these may contribute to the poorly characterized IONPs toxicity profile.

Corrigendum to the article titled “Metabolic Syndrome, Inflammation, and Cancer”.

This article critically discusses the role of Magnesium by reviewing recent literature and available data concerning the role of magnesium in neurological disorders. The authors summarize the role of Mg in neurological disorders to illustrate the symptoms caused by Mg-deficiency and the possible underlying mechanisms.

Article examines the roles of all major players in the biocompatibility of zinc, i.e., zinc phosphate (ZnP), zinc oxide (ZnO), zinc hydroxide (Zn(OH)2), pH, and Zn2+.

Article provides a brief summary of state-of-art of surface biofunctionalization on implantable metals by CaP coatings.

Article discusses the role of Mg2+ in regulating vascular functions.

Article describes study which indicates that nuclear type 2C protein phosphatase (PP2Cδ) impairs p53 acetylation and DNA damage response by compromising BRCA1 function in breast cancer development.

Article presents a 3D body imaging system built upon stereovision technology which utilizes paired, high-resolution single-lens reflex (SLR) cameras to image the front and back body surfaces of a person, and robust and efficient stereo matching algorithms to reconstruct the 3D surface of the body with high-density data clouds.

Article presents a simple 3D electroporation platform that enables massively parallel single-cell manipulation and the intracellular delivery of macromolecules and small molecules.

Article describes study which sought to evaluate methods for activity recognition for toddlers.

Article presents research where friction stir additive manufacturing technique was employed to fabricate AZ31B magnesium-hydroxyapatite composite. The study aims to evaluate effect of hydroxyapatite (HA, Ca₁₀(PO₄)₆OH₂), a ceramic similar to natural bone, into AZ31B Mg alloy matrix on biomineralization and biocompatibility.

Article presents research that creates an automatic repetition counting system that is flexible enough to measure multiple distinct and repeating movements during physical therapy without being trained on the specific motion.

This article presents a composite review involving some of the current and best treatments for colonic anastomotic leakage that are available in order to better understand the steps taken to treat this complication.

This article showcasing the editorial team welcomes all readers to the proceedings of International Conference on Recent Advancements in Biomedical Engineering (ICRABE-2021). The conference was inspired by the fusion of science and engineering principles in healthcare services and products. The conference aims to initiate exchange of innovative ideas between students, research scholar and faculties. Specifically, mechanical principles, power control for medical devices, nanomaterials and associated technologies were focused. This proceeding comprises of a broad spectrum of techniques to expose the recent advancements in the field of physics for healthcare application. A List of the Organizing Committee, Advisory Committee, Technical Committee are available in the pdf.

This article is a review that illustrates the involvement of MMP-13 in the initiation and progression of Osteoarthritis (OA) through the regulation of MMP-13 activity at the molecular and epigenetic levels, as well as the strategies that have been employed against MMP-13. The aim of this review is to identify MMP-13 as an attractive target for inhibitor development in the treatment of OA.

This article describes a system for pupil size estimation with a user interface to allow rapid adjustment of parameters and extraction of pupil parameters of interest in order to identify Parkinson's disease (PD) as early as possible.

Article evaluating whether advanced prostheses can provide better safety and performance capabilities to maintain and improve quality of life in individuals who are predominantly designated MFCL level K2. This study used a 13 month longitudinal clinical trial to determine the benefits of using a C-Leg and 1M10 foot in individuals at K2 level with transfemoral amputation due to vascular disease.

This article develops a molecular cell tracker with a strong fluorescence signal in the second near-infrared (NIR-II) window (1,000-1,700 nm) for real-time monitoring of in vivo cell behaviors in both healthy and diseased animal models to address the issue of precisely and quantitatively evaluating the in vivo cell distribution, migration, and engraftment in stem cell therapy.

This article explores a proposed deep-learning-based algorithm called DeepFilter for improving peptide identifications from a collection of tandem mass spectra. The authors find that DeepFilter is believed to generalize properly to new, previously unseen peptide-spectrum-matches and can be readily applied in peptide identification from metaproteomics data.

Data management plan for the grant "Modulating 3D Cellular Connectivity Via Spatially-Controlled Programmable Bonding." This project seeks to demonstrate proof-of-concept for technology that allows one to systematically place cells on substrates to create complex 3D assemblies with precise control over individual cellular interactions. The technology generated within this proposal will open new avenues for studying multicellular communication pathways, stem cell differentiation, and understanding developmental processes. Spatially-defined cell-cell communication plays a critical role in numerous disease and developmental processes that include osteoarthritic degeneration, cancer metastasis, and organ regeneration.

Data management plan for the grant "Development of Genetic Sensors and Circuits for Creating Novel Cellular Behaviors." This research is expected to advance the capability to engineer organisms for biomedical uses. Specifically, the outcomes of this project include design principles for engineering regulators from different protein families, an extensive set of genetic sensors for detecting a broad range of signals, and novel genetic circuits that address uprising problems in biomedical fields. It uses a novel multidisciplinary approach to enhance the health of the nation by creating tools that facilitate both medical-related discoveries and the implementation of new strategies for biomedical applications.