Data management plan for the grant, "UNT Texas Fashion Collection: Assessment and Preservation Training."

Data management plan for the grant, "CAREER: Shape Memory Polymers as Biomaterial." This CAREER projectaimsto elucidate the underlying mechanism of the plasticization-induced shape memory effect of thiol-enebased polymers. The model application for this material will be a heat shrink tubing that can shrink at bodily conditions (37° C and simulated body fluids) and can be used to seal colonic anastomosis. The specific three aims are to (1) Systematically investigate the effect of crosslink-density and chain extender length on theplasticization-induced shape memory effect of thiol-enebased polymers. Mechanical and thermomechanical measurements inside simulated body fluids will be used to assess shape memory properties and structure-property relationships. (2) Understand the relationship between material thickness, degree of shape-programming, and radial recovery forces of tube-shaped SMPs to determine optimal design parameters for sufficient shape recovery using the heat shrink tube model. (3) Demonstrate the functionality of a biomedical heat shrink tube that utilizes the plasticization-induced shape recovery through an ex vivo colon anastomosis model and quantify mechanical and sealing properties.

Data management plan for the grant, "New approach based on enzyme stimulating of peptides for targeting drug resistance breast cancers." In this project, we propose the development of selective self-assembling peptides that form nanofibers via a self-assembling process upon the action of Eyes absent (EYA) enzyme, specific to drug resistance Triple Negative Breast cancer cells (TNBC). The objectives are: Aim 1: Design and synthesize self-assembling peptide substrates for EYA enzymes; Aim 2:Determining the efficacy of peptide substrates for inhibiting TNBC in spheroid 3D cell cultures. The correlation between the enzyme kinetic and the activity of nanostructures for targeting EYA will be evaluated. Aim 3: The apoptosis response of the TNBC cells will be determined. This study will lead to finding the potent peptide substrate and the effective dose for inhibiting TNBC cells with apoptosis cell death.

Data management plan for the grant, "Mechanoregulators of Nanoparticle-Cell Interactions at Tissue Interfaces."

Data management plan for the grant, "Targeted Systemic Delivery of SDF-1 DNA for the Treatment of Chronic Heart Disease."