4 Matching Results

Results open in a new window/tab.

Flexible and Stretchable Bioelectronics (open access)

Flexible and Stretchable Bioelectronics

Article reviewing several several flexible and stretchable materials used as substrate, stretchable electrical conduits and encapsulation, design modifications for stretchability, fabrication techniques, methods of signal transmission and monitoring, and the power sources for these stretchable bioelectronics. Ultimately, these bioelectronic devices can be used for wide range of applications from skin bioelectronics and biosensing devices, to neural implants for diagnostic or therapeutic purposes.
Date: December 20, 2021
Creator: Chitrakar, Chandani; Hedrick, Eric; Adegoke, Lauren & Ecker, Melanie
Object Type: Article
System: The UNT Digital Library
On-chip multiplexed single-cell patterning and controllable intracellular delivery (open access)

On-chip multiplexed single-cell patterning and controllable intracellular delivery

Article presents a simple 3D electroporation platform that enables massively parallel single-cell manipulation and the intracellular delivery of macromolecules and small molecules.
Date: February 24, 2020
Creator: Dong, Zaizai; Jiao, Yanli; Xie, Bingteng; Hao, Yongcun; Wang, Pan; Liu, Yuanyuan et al.
Object Type: Article
System: The UNT Digital Library
Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis (open access)

Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis

This article is a review that illustrates the involvement of MMP-13 in the initiation and progression of Osteoarthritis (OA) through the regulation of MMP-13 activity at the molecular and epigenetic levels, as well as the strategies that have been employed against MMP-13. The aim of this review is to identify MMP-13 as an attractive target for inhibitor development in the treatment of OA.
Date: February 9, 2021
Creator: Hu, Qichan & Ecker, Melanie
Object Type: Article
System: The UNT Digital Library
CAREER: Shape Memory Polymers as Biomaterial (open access)

CAREER: Shape Memory Polymers as Biomaterial

Data management plan for the grant, "CAREER: Shape Memory Polymers as Biomaterial." This CAREER projectaimsto elucidate the underlying mechanism of the plasticization-induced shape memory effect of thiol-enebased polymers. The model application for this material will be a heat shrink tubing that can shrink at bodily conditions (37° C and simulated body fluids) and can be used to seal colonic anastomosis. The specific three aims are to (1) Systematically investigate the effect of crosslink-density and chain extender length on theplasticization-induced shape memory effect of thiol-enebased polymers. Mechanical and thermomechanical measurements inside simulated body fluids will be used to assess shape memory properties and structure-property relationships. (2) Understand the relationship between material thickness, degree of shape-programming, and radial recovery forces of tube-shaped SMPs to determine optimal design parameters for sufficient shape recovery using the heat shrink tube model. (3) Demonstrate the functionality of a biomedical heat shrink tube that utilizes the plasticization-induced shape recovery through an ex vivo colon anastomosis model and quantify mechanical and sealing properties.
Date: 2023-02-01/2028-01-31
Creator: Ecker, Melanie
Object Type: Text
System: The UNT Digital Library