Degree Department

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Pathological Targets for Treating Temporal Lobe Epilepsy: Discoveries From Microscale to Macroscale (open access)

Pathological Targets for Treating Temporal Lobe Epilepsy: Discoveries From Microscale to Macroscale

This review article summarizes the latest neuropathological discoveries at the molecular, cellular, and tissue levels involving both animal and patient studies, aiming to explore epileptogenesis and highlight new potential targets in the diagnosis and treatment of temporal lobe epilepsy (TLE).
Date: January 7, 2022
Creator: You, Jing; Huang, Haiyan; Chan, Clement T. Y. & Li, Lin
System: The UNT Digital Library
Bioabsorbable zinc ion induced biphasic cellular responses in vascular smooth muscle cells (open access)

Bioabsorbable zinc ion induced biphasic cellular responses in vascular smooth muscle cells

This article explores the short-term effects of extracellular Zn²⁺ on human smooth muscle cells.
Date: January 6, 2016
Creator: Ma, Jun; Zhao, Nan & Zhu, Donghui
System: The UNT Digital Library
Hedgehog signaling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells (open access)

Hedgehog signaling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells

Article states that although KRASG12C inhibitors have shown promising activity in lung adenocarcinomas harboring KRASG12C, acquired resistance to these therapies eventually occurs in most patients. The authors report that the hedgehog signal is induced by KRASG12C inhibitors and mediates KRAS re-expression in cancer cells treated with a KRASG12C inhibitor.
Date: January 16, 2024
Creator: Lee, Chaeyoung; Yi, Jawoon; Park, Jihwan; Ahn, Byungyong; Won, Young-Wook; Jeon, JiHeung et al.
System: The UNT Digital Library