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Review of Colonic Anastomotic Leakage and Prevention Methods
This article presents a composite review involving some of the current and best treatments for colonic anastomotic leakage that are available in order to better understand the steps taken to treat this complication.
Date:
November 3, 2020
Creator:
Fang, Alex H.; Chao, Wilson & Ecker, Melanie
System:
The UNT Digital Library
PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer
Article describes study which indicates that nuclear type 2C protein phosphatase (PP2Cδ) impairs p53 acetylation and DNA damage response by compromising BRCA1 function in breast cancer development.
Date:
October 16, 2019
Creator:
Li, Qun; Hao, Qiongyu; Cao, Wei; Li, Jieqing; Wu, Ke; Elshimali, Yahya et al.
System:
The UNT Digital Library
Hedgehog signaling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells
Article states that although KRASG12C inhibitors have shown promising activity in lung adenocarcinomas harboring KRASG12C, acquired resistance to these therapies eventually occurs in most patients. The authors report that the hedgehog signal is induced by KRASG12C inhibitors and mediates KRAS re-expression in cancer cells treated with a KRASG12C inhibitor.
Date:
January 16, 2024
Creator:
Lee, Chaeyoung; Yi, Jawoon; Park, Jihwan; Ahn, Byungyong; Won, Young-Wook; Jeon, JiHeung et al.
System:
The UNT Digital Library