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Evaluation of pathways to the C-glycosyl isoflavone puerarin in roots of kudzu (Pueraria montana lobata)
Article describes how kudzu produces both O- and C-glycosylated isoflavones, with puerarin (C-glucosyl daidzein) as an important bioactive compound. The authors go on to explain how expression of recombinant UGTs in Escherichia coli and candidate C-glycosyltransferases in Medicago truncatula were used to explore substrate specificities, and gene silencing of UGT and key isoflavone biosynthetic genes in kudzu hairy roots employed to test hypotheses concerning the substrate(s) for C-glycosylation.
Date:
September 2, 2022
Creator:
Adolfo, Laci M.; Burks, David J.; Rao, Xiaolan; Alvarez-Hernandez, Anislay & Dixon, R. A.
System:
The UNT Digital Library
Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ
This article reports the synthesis and related biological activity of novel dihydropyrimidones.
Date:
August 15, 2014
Creator:
Bharathkumar, Hanumantharayappa; Paricharak, Shardul; Dinesh, K. R.; Siveen, Kodappully Sivaraman; Fuchs, Julian E.; Rangappa, Shobith et al.
System:
The UNT Digital Library
Phenylalanine ammonia-lyase (PAL) from tobacco (Nicotiana tabacum): characterization of the four tobacco PAL genes and active heterotetrameric enzymes
Article on phenylalanine ammonia-lyase (PAL) from tobacco (Nicotiana tabacum) and characterization of the four tobacco PAL genes and active heterotetrameric enzymes.
Date:
September 2, 2009
Creator:
Reichert, Angelika I.; He, Xian-Zhi & Dixon, R. A.
System:
The UNT Digital Library