U N T Established 1890 U N T
University Libraries

Digital Collections

Degree Department

Year

Month

Day

1 Matching Results

Start Over Degree Department Biological Sciences Year 2022 Month February Day 23rd

Results open in a new window/tab.

Results: 1 - 1 of 1
Best Match Title Creator Date Created (Newest) Date Created (Oldest) Date Added (Newest) Date Added (Oldest)
In vivo Evaluation of Non-viral NICD Plasmid-Loaded PLGA Nanoparticles in Developing Zebrafish to Improve Cardiac Functions (open access)

In vivo Evaluation of Non-viral NICD Plasmid-Loaded PLGA Nanoparticles in Developing Zebrafish to Improve Cardiac Functions

This article presents a study with the purpose to deliver a Notch Intracellular Domain (NICD)-encoded plasmid via poly(lactic-co-glycolic acid) (PLGA) nanoparticles and to investigate the toxic environmental side effects for an in vivo experiment. This research demonstrates that PLGA nanoparticle-mediated target delivery to upregulate Notch related genes can be a potential therapeutic approach with minimum toxic effects.
Date: February 23, 2022
Creator: Messerschmidt, Victoria L.; Chintapula, Uday; Bonetesta, Fabrizio; Laboy-Segarra, Samantha; Naderi, Amir; Nguyen, Kytai T. et al.
System: The UNT Digital Library