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Parental transgenerational epigenetic inheritance related to dietary crude oil exposure in Danio rerio (open access)

Parental transgenerational epigenetic inheritance related to dietary crude oil exposure in Danio rerio

Article investigating the transgenerational inheritance from both parental lines in zebrafish. Adult zebrafish were separated into female and male groups exposed for 21 days to either a control diet or to a diet containing water accommodated fractions of crude oil. To determine the maternal and paternal influence on their offspring, the authors evaluated responses from molecular to whole organismal levels in both generations.
Date: January 22, 2020
Creator: Bautista, Naim M.; Crespel, Amélie; Crossley, Janna; Padilla, Pamela A. & Burggren, Warren W.
System: The UNT Digital Library
SEIPIN Isoforms Interact with the Membrane-Tethering Protein VAP27-1 for Lipid Droplet Formation (open access)

SEIPIN Isoforms Interact with the Membrane-Tethering Protein VAP27-1 for Lipid Droplet Formation

Article demonstrating that part of the function of two SEIPIN isoforms in Arabidopsis (Arabidopsis thaliana), AtSEIPIN2 and AtSEIPIN3, may depend on their interaction with the vesicle-associated membrane protein (VAMP)–associated protein (VAP) family member AtVAP27-1. The authors used a combination of biochemical, cell biology, and genetics approaches to show that AtVAP27-1 interacts with the N termini of AtSEIPIN2 and AtSEIPIN3 and likely supports the normal formation of LDs. This insight indicates that the ER membrane tethering machinery in plant cells could play a role with select SEIPIN isoforms in LD biogenesis at the ER, and additional experimental evidence in Saccharomyces cerevisiae supports the possibility that this interaction may be important in other eukaryotic systems.
Date: July 20, 2020
Creator: Greer, Michael Scott; Cai, Yingqi; Gidda, Satinder K.; Esnay, Nicolas; Kretzschmar, Franziska K.; Seay, Damien C. et al.
System: The UNT Digital Library