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803 Matching Results
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The complexities of proanthocyanidin biosynthesis and its regulation in plants
Article describes how proanthocyanidins (PAs) are natural flavan-3-ol polymers that contribute protection to plants under biotic and abiotic stress, benefits to human health, and bitterness and astringency to food products. This review extends the conventional understanding with recent findings that provide new insights to address lingering questions and focus strategies for manipulating PA traits in plants.
Date:
November 26, 2022
Creator:
Yu, Keji; Song, Yushuang; Lin, Jinxing & Dixon, R. A.
System:
The UNT Digital Library
Lipid Droplets: Packing Hydrophobic Molecules Within the Aqueous Cytoplasm
Article discusses how lipid droplets, also known as oil bodies or lipid bodies, are plant organelles that compartmentalize neutral lipids as a hydrophobic matrix covered by proteins embedded in a phospholipid monolayer. The authors review the growing body of knowledge about lipid droplets in plant cells, describe the evolutionary similarity and divergence in their associated subcellular machinery, and point to gaps that deserve future attention.
Date:
November 22, 2022
Creator:
Guzha, Athanas; Whitehead, Payton; Ischebeck, Till & Chapman, Kent Dean
System:
The UNT Digital Library
Transcriptomic profiling of miR-203a inhibitor and miR-34b-injected zebrafish (Danio rerio) validates oil-induced neurological, cardiovascular and eye toxicity response pathways
Article discusses how the global sequencing of microRNA (miRNA; miR) and integration to downstream mRNA expression profiles in early life stages (ELS) of fish following exposure to crude oil determined consistently dysregulated miRNAs regardless of the oil source or fish species. The overlay of differentially expressed miRNAs and mRNAs into in silico software determined that the key roles of these miRNAs were predicted to be involved in cardiovascular, neurological and visually-mediated pathways.
Date:
November 21, 2022
Creator:
Maguson, Jason T.; Leads, Rachel R.; McGruer, Victoria; Qian, Le; Tanabe, Philip; Roberts, Aaron P. et al.
System:
The UNT Digital Library
The protein conformational basis of isoflavone biosynthesis
Authors of the article assert that isoflavonoids play important roles in plant defense and also exhibit a range of mammalian health-promoting activities. They emphasize that understanding the structural basis of isoflavone biosynthesis will facilitate the engineering of new bioactive isoflavonoids.
Date:
November 15, 2022
Creator:
Wang, Xiaoqiang; Pan, Haiyun; Sagurthi, Someswar; Paris, Vincent; Zhuo, Chunliu & Dixon, R. A.
System:
The UNT Digital Library
A lipidomics platform to analyze the fatty acid compositions of non-polar and polar lipid molecular species from plant tissues: Examples from developing seeds and seedlings of pennycress (Thlaspi arvense)
Article describes a stepwise targeted lipidomics approach to characterize the polar and non-polar lipid classes using complementary LC-MS methods. This lipidomics workflow was applied to developing, mature, and germinated pennycress seeds/seedlings and found unexpected changes among several lipid molecular species.
Date:
November 9, 2022
Creator:
Romsdahl, Trevor B.; Cocuron, Jean-Christophe; Pearson, Mackenzie J.; Alonso, Ana Paula & Chapman, Kent Dean
System:
The UNT Digital Library
Identification of Novel Antimicrobial Resistance Genes Using Machine Learning, Homology Modeling, and Molecular Docking
Article claims antimicrobial resistance (AMR) threatens the healthcare system worldwide with the rise of emerging drug resistant infectious agents. To infer novel resistance genes, we used complete gene sets of several bacterial strains known to be susceptible or resistant to specific drugs and associated phenotypic information within a machine learning framework that enabled prioritizing genes potentially involved in resistance.
Date:
October 23, 2022
Creator:
Sunuwar, Janak & Azad, Rajeev K.
System:
The UNT Digital Library
Recurrent urinary tract infection and estrogen shape the taxonomic ecology and function of the postmenopausal urogenital microbiome
Article describes how postmenopausal women are severely affected by recurrent urinary tract infection (rUTI). The authors perform shotgun metagenomics and advanced culture on urine from a controlled cohort of postmenopausal women to identify urogenital microbiome compositional and function changes linked to rUTI susceptibility.
Date:
October 18, 2022
Creator:
Neugent, Michael D.; Kumar, Ashwani; Hulyalkar, Neha V.; Lutz, Kevin C.; Nguyen, Vivian H.; Fuentes, Jorge L. et al.
System:
The UNT Digital Library
Sustainable nutrition: a spatially explicit modeling approach for urban land use planning
Article describes how rapid urbanization has influenced the transformation of local and global food systems, altering the availability, access to, and distribution of healthy food. Micronutrient deficiency and hunger have been exacerbated worldwide. The author's research proposes a simulation strategy to evaluate the impact of agricultural land use and crop choices on nutritional production in rapidly growing urban areas.
Date:
October 14, 2022
Creator:
Torres, Angélica Torres; Tiwari, Chetan & Atkinson, Samuel F.
System:
The UNT Digital Library
Multi-omic characterization of bifunctional peroxidase 4-coumarate 3-hydroxylase knockdown in Brachypodium distachyon provides insights into lignin modification associated pleiotropic effects
Article discusses how a bifunctional peroxidase enzyme, 4-coumarate 3-hydroxylase (C3H/APX), provides a parallel route to the shikimate shunt pathway for the conversion of 4-coumarate to caffeate in the early steps of lignin biosynthesis. Here, a multi-omic approach was used to characterize molecular changes resulting from C3H/APX-KD associated lignin modification and negative growth phenotype in Brachypodium distachyon.
Date:
September 28, 2022
Creator:
Shrestha, Him K.; Fichman, Yosef; Engle, Nancy L.; Tschaplinski, Timothy J.; Mittler, Ron; Dixon, R. A. et al.
System:
The UNT Digital Library
Habitat amount or landscape configuration: Emerging HotSpot analysis reveals the importance of habitat amount for a grassland bird in South Dakota
The authors of the article used pheasants (Phasianus colchicus) across South Dakota, USA as a model species to identify environmental factors driving spatiotemporal variation in population productivity. They found that the amount of grassland at a local spatial scale was the primary factor influencing an area being a HotSpot.
Date:
September 26, 2022
Creator:
Harsh, Sprih; Lonsinger, Robert C. & Gregory, Andrew
System:
The UNT Digital Library
Complete Genome Sequences of the Novel Cluster BP Phages Infecting Streptomyces sanglieri, AxeJC, Cumberbatch, Eastland, Eklok, HFrancette, Ignacio, Piccadilly, and Vondra
Article describes the Streptomyces sanglieri bacteriophages AxeJC, Cumberbatch, Eastland,Eklok, HFrancette, Ignacio, Piccadilly, and Vondra form a novel actinobacteriophage cluster,BP. These siphoviruses have circularly permuted genomes with an average size of 37,700 bp and a GC content of 71%. Each genome contains approximately 58 protein-coding genes, with no tRNAs.
Date:
September 14, 2022
Creator:
Nath, Sreemoye; Sulaiman, Ahmad; Maneekul, Jindanuch; Bhuiyan, Swapan; Layton, Sonya R.; Menchaca, Carolina et al.
System:
The UNT Digital Library
Evaluation of pathways to the C-glycosyl isoflavone puerarin in roots of kudzu (Pueraria montana lobata)
Article describes how kudzu produces both O- and C-glycosylated isoflavones, with puerarin (C-glucosyl daidzein) as an important bioactive compound. The authors go on to explain how expression of recombinant UGTs in Escherichia coli and candidate C-glycosyltransferases in Medicago truncatula were used to explore substrate specificities, and gene silencing of UGT and key isoflavone biosynthetic genes in kudzu hairy roots employed to test hypotheses concerning the substrate(s) for C-glycosylation.
Date:
September 2, 2022
Creator:
Adolfo, Laci M.; Burks, David J.; Rao, Xiaolan; Alvarez-Hernandez, Anislay & Dixon, R. A.
System:
The UNT Digital Library
The Subantarctic Rayadito (Aphrastura subantarctica), a new bird species on the southernmost islands of the Americas
Article describes a new taxon of terrestrial bird of the genus Aphrastura (rayaditos) inhabiting the Diego Ramírez Archipelago, the southernmost point of the American continent. The authors state that the discovery of this endemic passerine highlights the need to monitor and conserve this still-pristine archipelago devoid of exotic species, which is now protected by the recently created Diego Ramírez Islands-Drake Passage Marine Park.
Date:
August 26, 2022
Creator:
Rozzi, Ricardo, 1960-; Quilodrán, Claudio S.; Botero-Delgadillo, Esteban; Napolitano, Constanza; Torres-Mura, Juan C.; Barroso, Omar et al.
System:
The UNT Digital Library
Environmental filtering of macroinvertebrate traits influences ecosystem functioning in a large river floodplain
Article describes how the biodiversity–ecosystem function hypothesis postulates that higher biodiversity is correlated with faster ecosystem process rates and increased ecosystem stability in fluctuating environments. The authors examined linkages among floodplain wetland habitats, invertebrate communities and their associated traits, and ecosystem function across 60 sites within the floodplain wetlands of the lower Wolastoq, Saint John River, New Brunswick.
Date:
August 20, 2022
Creator:
Rideout, Natalie K.; Compson, Zacchaeus Greg; Monk, Wendy A.; Brunce, Meghann R.; Hajibabaei, Mehrdad; Porter, Teresita M. et al.
System:
The UNT Digital Library
N-acylethanolamide metabolizing enzymes are upregulated in human neural progenitor-derived neurons exposed to sub-lethal oxidative stress
Article is a study determining whether ReN cells, a superior cell model system for studying neurodevelopment, differentiation, and neuroprotection, express proteins involved in canonical eCB NAE signaling and whether oxidative stress can induce their expression. This study is a first step toward determining how oxidative stress affects CB1, CB2, FAAH, NAAA, and NAPE-PLD expression and their potential defense against oxidative stress.
Date:
August 8, 2022
Creator:
Duncan, Scott R.; Riordan, Sean M.; Hall, Conner W.; Payne, Andrew J.; Chapman, Kent Dean & Koulen, Peter
System:
The UNT Digital Library
Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene
Article presents a case study of a 35 year-old Caucasian woman who experienced multiple vertebral fractures two months after her second pregnancy. The results suggest a potential role of heterozygous WNT1 variants in the pathogenesis of early-onset osteoporosis. The authors suggest that teriparatide is one of the most appropriate available therapies for such cases.
Date:
August 8, 2022
Creator:
Campopiano, Maria Cristina; Fogli, Antonella; Michelucci, Angela; Mazoni, Laura; Longo, Antonella; Borsari, Simona et al.
System:
The UNT Digital Library
The Cluster Transfer Function of AtNEET Supports the Ferredoxin–Thioredoxin Network of Plant Cells
This article develops an inducible expression system to study AtNEET function in mature plants using a time-course proteomics approach. The authors report that the suppression of AtNEET cluster transfer function results in drastic changes in the expression of different members of the ferredoxin (Fd), Fd-thioredoxin (TRX) reductase (FTR), and TRX network of Arabidopsis, as well as in cytosolic cluster assembly proteins.
Date:
August 6, 2022
Creator:
Zandalinas, Sara I.; Song, Luhua; Nechushtai, Rachel; Mendoza-Cózatl, David & Mittler, Ron
System:
The UNT Digital Library
Encroachment order and spatial patterns of broad-leaf tree species in the naturalization of a Cunninghamia lanceolata plantation
Authors of the article state that the aim of this study was to understand the encroachment order, spatial patterns, interspecific associations, and species diversity of a Cunninghamia lanceolata plantation and to provide context for how to improve the spatial structure of C. lanceolata plantations. Their results show that the encroachment of broad-leaf trees into the C. lanceolata plantation followed a clear successional sequence of tree community assembly: intolerant tree species encroachment first, such as Alniphyllum fortunei and Liquidambar formosana, encroached; neutral tree species then encroachment, such as Daphniphyllum oldhamii and Schima superba, and shade-tolerant tree species encroachment last, such as Castanopsis eyrei and Castanopsis tibetana.
Date:
August 3, 2022
Creator:
Zeng, Xiaoxia; Chen, Lin; Compson, Zacchaeus Greg; Li, Jiejun; Peng, Qiaohua; Gong, Chao et al.
System:
The UNT Digital Library
Finding new friends and revisiting old ones – how plant lipid droplets connect with other subcellular structures
Article talks about how the number of described contact sites between different subcellular compartments and structures in eukaryotic cells has increased dramatically in recent years, which has substantially reinforced the well-known premise that these kinds of connections are essential for overall cellular organization. The authors discuss contact sites involving plant lipid droplets (LDs), including LD-endoplasmic reticulum (ER) connections that mediate the biogenesis of new LDs at the ER, LD-peroxisome connections.
Date:
July 18, 2022
Creator:
Scholz, Patricia; Chapman, Kent Dean; Mullen, Robert T. & Ischebeck, Till
System:
The UNT Digital Library
Effective Mechanisms for Improving Seed Oil Production in Pennycress (Thlaspi arvense L.) Highlighted by Integration of Comparative Metabolomics and Transcriptomics
Article presents comparative biomass, metabolomic, and transcriptomic analyses between a high oil accession (HO) and low oil accession (LO) of pennycress to assess potential factors required to optimize oil content.
Date:
July 14, 2022
Creator:
Johnston, Christopher; García Navarrete, Tatiana; Ortiz, Emmanuel; Romsdahl, Trevor B.; Guzha, Athanas; Chapman, Kent Dean et al.
System:
The UNT Digital Library
Mediterranean Spur-Thighed Tortoises (Testudo graeca) Have Optimal Speeds at Which They Can Minimise the Metabolic Cost of Transport, on a Treadmill
Article experimentally quantifies the metabolic cost of transport in Mediterranean spur-thighed tortoises walking on a treadmill while also quantifying the kinematics of their movement. Results found that tortoises move more efficiently than predicted and presents the first data demonstrating a curvilinear cost of transport over their speed range. The authors conclude that tortoises have an optimum speed at which they move to minimise their metabolic cost of locomotion.
Date:
July 13, 2022
Creator:
Ewart, Heather; Tickle, Peter; Nudds, Robert; Sellers, William; Crossley, Dane A., II & Codd, Jonathan
System:
The UNT Digital Library
Comparing Methods of Defining Priority Areas for Greater Sage-Grouse
Article comparing priority areas for wildlife species using different methods and data types. The authors used resource selection function (RSF) models to predict high priority areas and compared this to priority areas developed using two alternative methods: (1) modified conservation buffer, and (2) utilization distribution (UD) models.
Date:
July 7, 2022
Creator:
Parsons, Lindsey; Jenks, Jonathan; Runia, Travis & Gregory, Andrew
System:
The UNT Digital Library
Retraction Note: Gold Nanoparticles‑enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa cells
The editors have retracted their article Gold Nanoparticles-enabled Efficient Dual Delivery of Anticancer Therapeutics to HeLa cells. Concerns were brought to the attention of the Editors with respect to apparent inappropriate manipulation of the data in seven of the nine panels shown in Figure 7. The Editors no longer have confidence in the data reported in this Article.
Date:
July 5, 2022
Creator:
Farooq, Muhammad U.; Novosad, Valentyn; Rozhkova, Elena A.; Wali, Hussain; Ali, Asghar; Fateh, Ahmed A. et al.
System:
The UNT Digital Library
Sustaining Human Nutrition in an Increasingly Urban World
This article proposes an urban nutrition (UN) extension to the previously published urban ecological economic system. The proposed extension can be used by decision makers worldwide to evaluate how landscape configurations and agricultural production systems affect the nutritional needs of the local population while fostering sustainable practices.
Date:
June 22, 2022
Creator:
Torres, Angélica Valencia; Tiwari, Chetan & Atkinson, Samuel F.
System:
The UNT Digital Library