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Optic-nerve-head (ONH) Chips for Glaucomatous Neurodegeneration (open access)

Optic-nerve-head (ONH) Chips for Glaucomatous Neurodegeneration

Data management plan for the grant, "Optic-nerve-head (ONH) Chips for Glaucomatous Neurodegeneration." The most prominent causative risk factor of glaucoma, the leading cause of irreversible blindness worldwide, is elevated intraocular pressure (IOP), which could deform the optic nerve head (ONH) and cause glaucomatous neurodegeneration. However, current glaucoma therapies that focus on lowering IOP do not stop vision loss effectively, and thus there is a pressing need to understand the mechanisms underlying glaucoma pathogenesis. In this project, we will develop a biomimetic 3-D ONH-on-a-chip system that closely mimics the key anatomical and pathophysiological characteristics of the native ONH to study astrocytic mechanisms of glaucoma pathogenesis, a missing link to develop efficacious therapies.
Date: 2022-09-30/2025-05-31
Creator: Yang, Yong
System: The UNT Digital Library
Exploring thermal properties of nanoscale wide bandgap semiconductors via  ultrafast thermal-emission spectroscopy (open access)

Exploring thermal properties of nanoscale wide bandgap semiconductors via ultrafast thermal-emission spectroscopy

Data management plan for the grant, "Exploring thermal properties of nanoscale wide bandgap semiconductors via ultrafast thermal-emission spectroscopy." In this project, we aim to develop a new thermometrology technique based on ultrafast thermal emission to directly and accurately measure thermal properties of thin-film wide bandgap semiconductors.
Date: 2023-09-30/2025-09-29
Creator: Xiao, Yuzhe
System: The UNT Digital Library