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17β-Estradiol Delivered in Eye Drops: Evidence of Impact on Protein Networks and Associated Biological Processes in the Rat Retina through Quantitative Proteomics (open access)

17β-Estradiol Delivered in Eye Drops: Evidence of Impact on Protein Networks and Associated Biological Processes in the Rat Retina through Quantitative Proteomics

Study analyzes target engagements through the identification of functional protein networks impacted after delivery of 17β-estradiol in eye drops to facilitate the development of broad-spectrum retina neuroprotectants that can be delivered through topical dosage forms.
Date: January 27, 2020
Creator: Prókai, László, 1958-; Zaman, Khadiza; Nguyen, Vien & Prokai-Tatrai, Katalin
System: The UNT Digital Library
HIV-1 Impairment via UBE3A and HIV-1 Nef Interactions Utilizing the Ubiquitin Proteasome System (open access)

HIV-1 Impairment via UBE3A and HIV-1 Nef Interactions Utilizing the Ubiquitin Proteasome System

Study examines the interaction between a key pathogenic HIV-1 viral protein, Nef, and ubiquitin (Ub)-protein ligase E3A (UBE3A).
Date: November 27, 2019
Creator: Pyeon, Dohun; Rojas, Vivian K.; Price, Lenore; Kim, Seongcheol; Singh, Meharvan & Park, In-Woo
System: The UNT Digital Library