This contract provides the research support for a group concerned with a relatively large range of problems. The integrating thread that runs through it is that of an interest in development and its genetic regulation, mainly in complex organisms and with an emphasis on the immune system as a model for developmental analysis and as a tool for following the development of other systems, especially the brain. It includes studies of biochemical genetics, primarily from a developmental viewpoint and with particular regard to defense mechanisms, and cellular aspects of the immune system. It extends into the area of cancer immunology and cell specificities as related to tumor systems, primarily from an immunogenetic viewpoint and with particular reference to leukemias in the mouse, and to disruptions of genetic control mechanisms in tumor development, especially as approached through the reappearance of fetal antigens associated with tumor development.

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This report presents developments related to four types of Information systems available to the members of congress.

This manual is intended as a basis for plutonium-238 recovery costs and as a guide for removal of plutonium-bearing wastes from the gloveboxes to be safely and economically discarded. Waste materials contaminated with plutonium-238 are generated from in-house production, analytical, process development, recovery and receipts from off-site. The contaminated materials include paper, rags, alpha-box gloves, piping, valves, filters, etc. General categories for all types of plutonium waste have been established by the ERDA and are reflected in this manual. There are numerous processes used in plutonium recovery, such as dissolution, ultrasonic cleaning, ion exchange, etc. One or more of these processes are needed to extract the plutonium-238 from waste materials, purify it and convert it to an oxide acceptable for reuse. This manual is presented in two parts: Part I gives a breakdown and brief explanation of the direct costs for plutonium-238 I recovery, derived from budget data. Direct costs include direct labor (operating personnel), operational materials and supplies, health physics direct labor, calorimetry labor, analytical labor, and engineering direct labor (total costs for Method I). Budgeted costs for labor and material were used in the derivation of discard limits. The data presented is then used to calculate the cost …