The x-ray diffraction (XRD) data from 200/sup 0/C/2h-aged uranium-6.5 wt % niobium (U-6.5Nb) alloys, taken under stress as a function of strain, revealed a gamma-zero (..gamma../sup 0/)..-->.. alpha prime-prime (..cap alpha..'') thermoelastic martensitic phase transformation. It was concluded that the primary reversible deformation modes consisted of the movement of ..gamma../sup 0//..cap alpha..'' interphase interfaces and ..cap alpha..'' intervariant interfaces. Specimen elasticity at low strains was associated with the retreat of interphase interfaces. At higher strains, interphase interfaces did not recover significantly on unloading, and elasticity was due primarily to the retreat of ..cap alpha..'' intervariant interfaces.

Flow cytometric assays of human erythrocytes labeled with monoclonal antibodies specific for glycophorin A were used to enumerate variant cells that appear in peripheral blood as a result of somatic gene-loss mutations in erythrocyte precursor cells. The assay was performed on erythrocytes from 10 oncology patients who had received at least one treatment from radiation or mutagenic chemotherapy at least 3 weeks before being assayed. The patients were suffering from many different malignancies (e.g., breast, renal, bone, colon and lung), and were treated with several different mutagenic therapeutics (e.g., cisplatinum, adriamycin, daunomycin, or cyclophosphamide). The frequency of these variant cells is an indication of the amount of mutagenic damage accumulated in the individual's erythropoietic cell population. Comparing these results to HPRT clonogenic assays, we find similar baseline frequencies of somatic mutation as well as similar correlation with mutagenic exposures. 9 refs., 3 figs., 1 tab.

We have designed, developed, and calibrated three different types of nondestructive assay systems for the Savannah River Plant (SRP). These systems will be delivered to SRP in 1986 and become part of the nuclear material accounting instrumentation at one of SRP's reprocessing facilities. Among the various types of nondestructive assay systems to be implemented are a neutron counter (Los Alamos National Laboratory - LANL), a four-station calorimeter (Mound Laboratories), a waste solution assay system (LANL), two gamma-ray solution concentration assay systems (LLNL), two x-ray fluorescence analysis concentration assay systems (LLNL), and one 2-detector plutonium solids isotopics system (LLNL). Los Alamos also has the responsibility of combining the individual measurement systems into an integrated accountability capability. Each NDA instrument will report results to a central Instrument Control Computer (ICC). Figure 1 illustrates schematically the integrated system with each Laboratory's contribution shown by dotted lines.