Article discussing research on BOV, a web-based BLAST output visualization tool.

Article on a cytochrome P450 monooxygenase commonly used for negative selection in transgenic plants causing growth anomalies by disrupting brassinosteroid signaling.

Article on key cell signaling pathways modulated by zerumbone and the role in the prevention and treatment of cancer.

Article on targeted down-regulation of cytochrome P450 enzymes for forage quality improvement in alfalfa (Medicago sativa L.).

This article reports on the characterization of the different antioxidant mechanisms of tomato plants subjected to heat stress, salinity stress, or a combination of both stresses.

This article determines the circulating leukocyte subset response to completing the 2013 Hotter'N Hell Hundred recreational 164-km road cycle event in a hot and humid environmental condition.

This article establishes the de novo transcriptomic database from the embryos and larvae of mahi-mahi exposed to water accommodated fractions (HEWAFs) of two Deepwater Horizon oil types (weathered and source oil) in an effort to advance understanding of the molecular aspects involved during specific toxicity responses.

This article contains an analysis of 16 microstatellite loci from 300 Greater Sage-Grouse individuals to assess genetic structure among populations in Wyoming and southeast Montana.

This article contains a study to determine if 30-d of oral spore-based probiotic supplementation could reduce dietary endotoxemia.

This article examines the hypothesis that MtNIP/LATD may have another biochemical activity.

This article documents the presence of the common wasp V. vulgaris on Navarino Island, Cape Horn Biosphere Reserve, Southern Chile.

This column article discusses the impact of Robert Boutillier and Graham Shelton's 1986 Journal of Experimental Biology paper "Gas exchange, storage and transport in voluntarily diving Xenopus laevis."

The article looks at antitumor activity using a matched pair of cell lines MDA-MB-231 cells that are estrogen-independent, estrogen receptor negative and MCF-7 cells, a cell line that is estrogen receptor (ER) positive. Those polyethers that contained a O-phenyl unit were able to significantly inhibit the non-estrogen sensitive cell line but were much less effective against the estrogen sensitive cell line; that is, the human breast cancer cell line MDA-MB-231 showed better test results for polymers derived from diols containing the O-phenyl moiety than the breast cancer cell line MCF-7, a well-characterized estrogen receptor positive control cell line.

This article presents a study in which an in silico genome-scale metabolic model of steroidogenesis is used to investigate the effects of hypoxic stress on steroid hormone productions in fish. This article introduces a powerful model for pathway analysis that can lend insights on the effects of various stressor scenarios on metabolic functions.

This article measures the cardiac performance of Newfoundland Atlantic cod (Gadus morhua). The results: (1) show that maximum performance of the isolated cod heart is not compromised by exposure to cold temperatures; and (2) support data from other studies, which show that, in contrast to salmonids, cod cardiac performance/myocardial contractility is not dependent upon humoral adrenergic stimulation.

Article investigating exposure to traffic-generated emissions and the potential to alter lung microbiota and immune defenses. Results show that the combined effects of ME and HF diet result in decreased immune surveillance and lung bacterial dysbiosis, which is of significance in lung diseases.

This article investigates the hypothesis that exposure to engine emissions increases systemic and local adipocyte RAS signaling, promoting the expression of factors involved in cardiovascular disease and obesity.

Article describing a novel S6 kinase isolated from human placenta which autoactivates through autophosphorylation in vitro. The data supports the hypothesis that this previously uncharacterized S6 kinase belongs to a unique family of protein kinases which utilize autophosphorylation as part of their in vivo activation mechanism.

Article evaluating the selectivity of compounds originally identified as inhibitors of poly(ADP-ribose) polymerase on members of the three classes of enzymes. The results suggest that micromolar levels of the benzamides in the culture medium should allow selective inhibition of poly(ADP-ribose) metabolism in intact cells. Furthermore, comparative quantitative inhibition studies should prove useful for assigning the biological effects of these inhibitors as an effect on either poly(ADP-ribose) or mono(ADP-ribose) metabolism.

Article presents a study where whole transcriptome sequencing (RNA-seq) and differential expression analysis were used to identify early (1–3 hr) transcriptional changes induced by the exogenous treatment of NAE 18:2 and NAE 18:3 in cotyledons, roots, and seedlings.

Article is a study exploring the possibility of using the tobacco retrotransposon Tnt1 to create a transposon-based insertion mutant population in B. distachyon.

This article shows that both Cys-EC and 4β-(S-cysteinyl)-catechin (Cys-C) are present in grapevine. The data from this study advance knowledge of PA building blocks and LAR function and provide targets for grapevine breeding to alter PA composition.

Authors of the article assert that isoflavonoids play important roles in plant defense and also exhibit a range of mammalian health-promoting activities. They emphasize that understanding the structural basis of isoflavone biosynthesis will facilitate the engineering of new bioactive isoflavonoids.