This report discusses relations between the U.S. and Mexico following the escape and recapture of Joaquín "El Chapo" Guzmán from a maximum security federal prison near Mexico City in July 2015. One key concern for U.S. policymakers is whether the Mexican government will be able to hold Guzmán securely in the same prison from which he escaped and then extradite him swiftly to the United States--a source of tension in U.S.-Mexican relations. Another is whether Guzmán's recapture, which was supported by U.S. intelligence, will lead to closer security cooperation moving forward.