Interview with Dr. Tao-Chiuh Hsu, continuing his reflections regarding his career at M.D. Anderson. The interview begins with a discussion of Dr. Felix Haas and the evolution of the department of biology. William R. Brinkley’s contributions and interactions with the department are recounted as well. Several of Dr. Hsu’s major accomplishments to science are highlighted including the development of chromosomal banding techniques, biological specimen banks, and cell preservation. The interview continues with a discussion of his sentiments regarding the re-organization of cell biology and his laboratory location within the Hermann Professional Building. A discussion regarding the collection of tissue samples from cats ends the interview. Several humorous stories regarding his personal life and work are also shared.