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Prodrugs of Thyrotropin-Releasing Hormone and Related Peptides as Central Nervous System Agents
This article is a review of prodrug design for brain delivery of small- and medium-sized neuropeptides, focusing on thyrotropin-releasing hormone and structurally related peptides as examples.
Date:
February 6, 2009
Creator:
Prokai-Tatrai, Katalin & Prókai, László, 1958-
System:
The UNT Digital Library
Treatment and Prevention of Recurrent Clostridium difficile Infection with Functionalized Bovine Antibody-Enriched Whey in a Hamster Primary Infection Model
This article focuses on the development of an alternative drug for the treatment of Clostridium difficile infection (CDI). Oral administration of anti-CD-WPI is a functional therapy of CDI in infected hamsters for both primary treatment and prevention of recurrence. Thus, anti-CD-WPI could address the urgent unmet medical need for treating and preventing recurrent CDI in humans.
Date:
February 6, 2019
Creator:
Heidebrecht, Hans-Jürgen; Weiss, William J.; Pulse, Mark; Lange, Anton; Gisch, Karina; Kliem, Heike et al.
System:
The UNT Digital Library