The Implications of Cancer Stem Cells for Cancer Therapy (open access)

The Implications of Cancer Stem Cells for Cancer Therapy

This review summarizes the characteristics, evidences and development of CSCs, as well as implications and challenges for cancer treatment. Surgery, radiotherapy and chemotherapy are universally recognized as the most effective anti-cancer therapies. Recent studies have showed that cancer stem cells (CSCs), a small subpopulation of tumor cells, can generate bulk populations of nontumorigenic cancer cell progeny through the self-renewal and differentiation processes.
Date: December 5, 2012
Creator: Jiang, Wenjing; Peng, Jianhua; Zhang, Yue; Cho, William C. S. & Jin, Kunlin
System: The UNT Digital Library
Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice (open access)

Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice

Study investigated the role of the neuroprotective kynurenic acid (KYNA) in RGC death against retinal ischemia/reperfusion (I/R) injury.
Date: March 5, 2020
Creator: Nahomi, Rooban B.; Nam, Mi-Hyun; Rankenberg, Johanna; Rakete, Stefan; Houck, Julie A.; Johnson, Ginger C. et al.
System: The UNT Digital Library