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01-ERD-111 - The Development of Synthetic High Affinity Ligands (open access)

01-ERD-111 - The Development of Synthetic High Affinity Ligands

The aim of this project was to develop Synthetic High-Affinity Ligands (SHALs), which bind with high affinity and specificity to proteins of interest for national security and cancer therapy applications. The aim of producing synthetic ligands for sensory devices as an alternative to antibody-based detection assays and therapeutic agents is to overcome the drawbacks associated with antibody-based in next-generation sensors and systems. The focus area of the project was the chemical synthesis of the SHALs. The project concentrated on two different protein targets. (a) The C fragment of tetanus and botulinum toxin, potential biowarfare agents. A SHAL for tetanus or botulinum toxin would be incorporated into a sensory device for the toxins. (b) HLA-DR10, a protein found in high abundance on the surface of Non-Hodgkins Lymphoma. A SHAL specific to a tumor marker, labeled with a radionuclide, would enable the targeted delivery of radiation therapy to metastatic disease. The technical approach used to develop a SHAL for each protein target will be described in more detail below. However, in general, the development of a SHAL requires a combination of computational modeling techniques, modern nuclear magnetic resonance spectroscopy (NMR) and synthetic chemistry.
Date: February 5, 2004
Creator: Perkins, J; Balhorn, R; Cosman, M; Lightstone, F & Zeller, L
Object Type: Report
System: The UNT Digital Library

E-5 E-One (2-5-1992)

None
Date: February 5, 1992
Creator: unknown
Object Type: Photograph
System: The Gateway to Oklahoma History
60-day waste compatibility safety issues and final results for TX-244 grab samples (open access)

60-day waste compatibility safety issues and final results for TX-244 grab samples

Three grab samples (244-TX-96-1, 244-TX-96-2, and 244-TX-96-3) were taken from Riser 8 of Tank 241-TX-244 on October 18, 1996, and received by 222-S Laboratory on October 18, 1996. These samples were analyzed in accordance with Compatibility Grab Sampling and Analysis Plan (TSAP) and Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) in support ofthe Waste Compatibility Program. Notifications were made in accordance with TSAP for pH and OH- analyses. Upon further review, the pH notification was deemed unnecessary, as the notification limit did not apply to this tank.
Date: February 5, 1997
Creator: Nuzum, J. L.
Object Type: Report
System: The UNT Digital Library
15th Street News (Midwest City, Okla.), Vol. 5, No. 10, Ed. 1 Thursday, February 5, 1976 (open access)

15th Street News (Midwest City, Okla.), Vol. 5, No. 10, Ed. 1 Thursday, February 5, 1976

Newspaper from Oscar Rose Junior College in Midwest City, Oklahoma that includes national, local, and campus news along with advertising.
Date: February 5, 1976
Creator: Bean, Willie
Object Type: Newspaper
System: The Gateway to Oklahoma History
15th Street News (Midwest City, Okla.), Vol. 16, No. 17, Ed. 1 Friday, February 5, 1988 (open access)

15th Street News (Midwest City, Okla.), Vol. 16, No. 17, Ed. 1 Friday, February 5, 1988

Newspaper from Rose State College in Midwest City, Oklahoma that includes national, local, and campus news along with advertising.
Date: February 5, 1988
Creator: Patrick, Lurah
Object Type: Newspaper
System: The Gateway to Oklahoma History
15th Street News (Midwest City, Okla.), Vol. 28, No. 16, Ed. 1 Friday, February 5, 1999 (open access)

15th Street News (Midwest City, Okla.), Vol. 28, No. 16, Ed. 1 Friday, February 5, 1999

Newspaper from Rose State College in Midwest City, Oklahoma that includes national, local, and campus news along with advertising.
Date: February 5, 1999
Creator: Pace, Joshua
Object Type: Newspaper
System: The Gateway to Oklahoma History
15th Street News (Midwest City, Okla.), Vol. 39, No. 17, Ed. 1 Friday, February 5, 2010 (open access)

15th Street News (Midwest City, Okla.), Vol. 39, No. 17, Ed. 1 Friday, February 5, 2010

Newspaper from Rose State College in Midwest City, Oklahoma that includes national, local, and campus news along with advertising.
Date: February 5, 2010
Creator: Price, Racheal
Object Type: Newspaper
System: The Gateway to Oklahoma History
The 2018 National Defense Strategy (open access)

The 2018 National Defense Strategy

This report discusses the 2018 National Defense Strategy which lays out the goals and methods of the Defense Department for the year.
Date: February 5, 2018
Creator: McInnis, Kathleen J.
Object Type: Report
System: The UNT Digital Library
21st Century Community Learning Centers: Background and Funding (open access)

21st Century Community Learning Centers: Background and Funding

This report summarizes the reauthorized Elementary and Secondary Education Act (ESEA) which contains the 21st Century Community Learning Centers (21st CCLC) program. The report covers the history of the ESEA as well as what is new in the reauthorization. Moreover, the report includes how grants are selected now, and the new focus of the program which is now exclusively for after-school-hours activities for children.
Date: February 5, 2008
Creator: McCallion, Gail
Object Type: Report
System: The UNT Digital Library
78th Texas Legislature, Regular Session, House Concurrent Resolution 26 (open access)

78th Texas Legislature, Regular Session, House Concurrent Resolution 26

Concurrent resolution introduced by the Texas House of Representatives and Senate relating to honoring soldiers from Fort Hood who are being deployed for Operation Enduring Freedom.
Date: February 5, 2003
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History
78th Texas Legislature, Regular Session, Senate Concurrent Resolution 4 (open access)

78th Texas Legislature, Regular Session, Senate Concurrent Resolution 4

Concurrent resolution introduced by the Texas Senate and House of Representatives relating to January 13 through January 26, 2003, as the Texas Centennial of Flight Celebration.
Date: February 5, 2003
Creator: Texas. Legislature. Senate.
Object Type: Legislative Document
System: The Portal to Texas History
84th Texas Legislature, Regular Session, House Concurrent Resolution 44 (open access)

84th Texas Legislature, Regular Session, House Concurrent Resolution 44

Concurrent resolution introduced by the Texas House of Representatives and Senate in memory of U.S. Army Sergeant Gilberto Lopez Sanchez of New Braunfels.
Date: February 5, 2015
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History
84th Texas Legislature, Regular Session, House Concurrent Resolution 45 (open access)

84th Texas Legislature, Regular Session, House Concurrent Resolution 45

Concurrent resolution introduced by the Texas House of Representatives and Senate granting the legislature permission to adjourn for more than three days.
Date: February 5, 2015
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History
84th Texas Legislature, Regular Session, House Concurrent Resolution 48 (open access)

84th Texas Legislature, Regular Session, House Concurrent Resolution 48

Concurrent resolution introduced by the Texas House of Representatives and Senate inviting the governor to address a joint session of the legislature on February 17, 2015.
Date: February 5, 2015
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History
84th Texas Legislature, Regular Session, Senate Concurrent Resolution 3 (open access)

84th Texas Legislature, Regular Session, Senate Concurrent Resolution 3

Concurrent resolution introduced by the Texas House of Representatives and Senate providing for procedures for the canvass of votes for the governor and lieutenant governor and the inauguration of the governor and lieutenant governor, and inviting the governor to address a joint session of the legislature on January 15, 2015.
Date: February 5, 2015
Creator: Texas. Legislature. Senate.
Object Type: Legislative Document
System: The Portal to Texas History
84th Texas Legislature, Regular Session, Senate Concurrent Resolution 4 (open access)

84th Texas Legislature, Regular Session, Senate Concurrent Resolution 4

Concurrent resolution introduced by the Texas House of Representatives and Senate granting the legislature permission to adjourn for more than three days during the period beginning on Thursday, January 15, 2015, and ending on Tuesday, January 20, 2015.
Date: February 5, 2015
Creator: Texas. Legislature. Senate.
Object Type: Legislative Document
System: The Portal to Texas History
86th Texas Legislature, Regular Session, House Concurrent Resolution 38 (open access)

86th Texas Legislature, Regular Session, House Concurrent Resolution 38

Concurrent resolution introduced by the Texas House of Representatives and Senate inviting the governor to address a joint session of the legislature on February 5, 2019.
Date: February 5, 2019
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History
86th Texas Legislature, Regular Session, House Concurrent Resolution 39 (open access)

86th Texas Legislature, Regular Session, House Concurrent Resolution 39

Concurrent resolution introduced by the Texas House of Representatives and Senate inviting the chief justice of the Supreme Court of Texas to address a joint session of the legislature on February 6, 2019.
Date: February 5, 2019
Creator: Texas. Legislature. House of Representatives.
Object Type: Legislative Document
System: The Portal to Texas History

[Abby Davis signing volleyball scholarship agreement]

Photograph of 4 women posing in front of a Lee College sign in the Lee College gymnasium. Back of photo reads, "Abby Davis, who will graduate this spring from Willis High School, signs a scholarship agreement to attend Lee College in Baytown and play volleyball for 1998-99. Tracie Johnson, seated left, coaches volleyball for Lee College. Standing are Davis' grandmother, Wanda Mabry (left) and Davis' mother, Lana McDaniel. Not pictured are grandfather C.D. Mabry and stepfather Oliver McDaniel. Davis, a defensive specialist and captain of her high school team this year, was the district's Most Valuable Defensive Player and made 1st team All-Montgomery County in 1997. 2-5-98"
Date: February 5, 1998
Creator: Lee College
Object Type: Photograph
System: The Portal to Texas History
Abilene Daily Reporter (Abilene, Tex.), Vol. 12, No. 168, Ed. 1 Wednesday, February 5, 1908 (open access)

Abilene Daily Reporter (Abilene, Tex.), Vol. 12, No. 168, Ed. 1 Wednesday, February 5, 1908

Daily newspaper from Abilene, Texas that includes local, state, and national news along with advertising.
Date: February 5, 1908
Creator: Shook, L. B.
Object Type: Newspaper
System: The Portal to Texas History
Abilene Daily Reporter (Abilene, Tex.), Vol. 13, No. 152, Ed. 1 Friday, February 5, 1909 (open access)

Abilene Daily Reporter (Abilene, Tex.), Vol. 13, No. 152, Ed. 1 Friday, February 5, 1909

Daily newspaper from Abilene, Texas that includes local, state, and national news along with advertising.
Date: February 5, 1909
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Abilene Daily Reporter (Abilene, Tex.), Vol. 14, No. 146, Ed. 1 Saturday, February 5, 1910 (open access)

Abilene Daily Reporter (Abilene, Tex.), Vol. 14, No. 146, Ed. 1 Saturday, February 5, 1910

Daily newspaper from Abilene, Texas that includes local, state, and national news along with advertising.
Date: February 5, 1910
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Abilene Daily Reporter (Abilene, Tex.), Vol. 15, No. 129, Ed. 1 Sunday, February 5, 1911 (open access)

Abilene Daily Reporter (Abilene, Tex.), Vol. 15, No. 129, Ed. 1 Sunday, February 5, 1911

Daily newspaper from Abilene, Texas that includes local, state, and national news along with advertising.
Date: February 5, 1911
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Abilene Daily Reporter (Abilene, Tex.), Vol. 16, No. 134, Ed. 1 Monday, February 5, 1912 (open access)

Abilene Daily Reporter (Abilene, Tex.), Vol. 16, No. 134, Ed. 1 Monday, February 5, 1912

Daily newspaper from Abilene, Texas that includes local, state, and national news along with advertising.
Date: February 5, 1912
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History