Economic Benefits, Carbon Dioxide (CO2) Emissions Reductions, and Water Conservation Benefits from 1,000 Megawatts (MW) of New Wind Power in Pennsylvania (Fact Sheet) (open access)

Economic Benefits, Carbon Dioxide (CO2) Emissions Reductions, and Water Conservation Benefits from 1,000 Megawatts (MW) of New Wind Power in Pennsylvania (Fact Sheet)

The U.S. Department of Energy?s Wind Powering America Program is committed to educating state-level policymakers and other stakeholders about the economic, CO2 emissions, and water conservation impacts of wind power. This analysis highlights the expected impacts of 1000 MW of wind power in Pennsylvania. Although construction and operation of 1000 MW of wind power is a significant effort, six states have already reached the 1000-MW mark. We forecast the cumulative economic benefits from 1000 MW of development in Pennsylvania to be $1.2 billion, annual CO2 reductions are estimated at 3.4 million tons, and annual water savings are 1,837 million gallons.
Date: October 1, 2008
Creator: unknown
Object Type: Report
System: The UNT Digital Library
CHARICE version 1.1 update. (open access)

CHARICE version 1.1 update.

CHARICE (CHARacteristics-based inverse analysis of Isentropic Compression Experiments) is a computer application, previously documented in SAND2007-4948, that analyzes velocity waveform data from ramp-wave experiments to determine a material's quasi-isentropic loading response in stress and density using an iterative characteristics-based approach. This short report documents only the changes in CHARICE release version 1.1 relative to release version 1.0, and is not intended to stand alone. CHARICE version 1.1 corrects an error in the algorithm of the method, fixes several bugs, improves robustness and performance, provides more useful error descriptions, and adds a number of minor features.
Date: October 1, 2008
Creator: Davis, Jean-Paul
Object Type: Report
System: The UNT Digital Library
Clean Cities: Ethanol Basics, Fact Sheet, October 2008 (open access)

Clean Cities: Ethanol Basics, Fact Sheet, October 2008

Document answers frequently asked questions about ethanol as a transportation fuel, including those on production, environmental effects, and vehicles.
Date: October 1, 2008
Creator: unknown
Object Type: Report
System: The UNT Digital Library
In-situ scanning probe microscopy of electrodeposited nickel. (open access)

In-situ scanning probe microscopy of electrodeposited nickel.

The performance characteristics and material properties such as stress, microstructure, and composition of nickel coatings and electroformed components can be controlled over a wide range by the addition of small amounts of surface-active compounds to the electroplating bath. Saccharin is one compound that is widely utilized for its ability to reduce tensile stress and refine grain size in electrodeposited nickel. While the effects of saccharin on nickel electrodeposition have been studied by many authors in the past, there is still uncertainty over saccharin's mechanisms of incorporation, stress reduction, and grain refinement. In-situ scanning probe microscopy (SPM) is a tool that can be used to directly image the nucleation and growth of thin nickel films at nanometer length scales to help elucidate saccharin's role in the development and evolution of grain structure. In this study, in-situ atomic force microscopy (AFM) and scanning tunneling microscopy (STM) techniques are used to investigate the effects of saccharin on the morphological evolution of thin nickel films. By observing mono-atomic height nickel island growth with and without saccharin present we conclude that saccharin has little effect on the nickel surface mobility during deposition at low overpotentials where the growth occurs in a layer-by-layer mode. Saccharin was …
Date: October 1, 2004
Creator: Kelly, James J. & Dibble, Dean C.
Object Type: Report
System: The UNT Digital Library
Geometric optimization of the 56 MHz SRF cavity and its frequency table (open access)

Geometric optimization of the 56 MHz SRF cavity and its frequency table

It is essential to know the frequency of a Superconducting Radio Frequency (SRF) cavity at its 'just being fabricated' stage because frequency is the key parameter in constructing the cavity. In this paper, we report our work on assessing it. We can estimate the frequency change from stage to stage theoretically and/or by simulation. At the operating stage, the frequency can be calculated accurately, and, from this value, we obtain the frequencies at other stages. They are listed in a table that serves to check the processes from stage to stage. Equally important is optimizing the geometric shape of the SRF cavity so that the peak electric-field and peak magnetic-field are as low as possible. It is particularly desirable in the 56MHz SRF cavity of RHIC to maximize the frequency sensitivity of the slow tuner. After undertaking such optimization, our resultant peak electric-field is only 44.1MV/m, and the peak magnetic-field is 1049G at 2.5MV of voltage across the cavity gap. To quench superconductivity in an SRF cavity, it is reported that the limit of the peak magnetic-field is 1800G [1], and that of the peak electric-field is more than l00MV/m for a SRF cavity [2]. Our simulations employed the codes …
Date: October 1, 2008
Creator: Chang, X. & Ben-Zvi, Ilan
Object Type: Report
System: The UNT Digital Library
Shillapoo Wildlife Area, Annual Report 2007-2008. (open access)

Shillapoo Wildlife Area, Annual Report 2007-2008.

This report summarizes accomplishments, challenges and successes on WDFW's Shillapoo Wildlife Area funded under Bonneville Power Administration's (BPA) Wildlife Mitigation Program (BPA project No.2003-012-00) during the Fiscal Year 08 contract period October 1, 2007-September 30, 2008. The information presented here is intended to supplement that contained in BPA's PISCES contract development and reporting system. The organization below is by broad categories of work but references are made to individual work elements in the PISCES Statement of Work as appropriate. Significant progress was realized in almost all major work types. Of particular note was progress made in tree plantings and pasture rehabilitation efforts. This year's tree planting effort included five sites detailed below and in terms of the number of plants was certainly the largest effort on the wildlife area to date in one season. The planting itself took a significant amount of time, which was anticipated. However, installation of mats and tubes took much longer than expected which impacted planned fence projects in particular. Survival of the plantings appears to be good. Improvement to the quality of waterfowl pasture habitats is evident on a number of sites due to replanting and weed control efforts. Continuing long-term weed control efforts will …
Date: October 1, 2007
Creator: Calkins, Brian
Object Type: Report
System: The UNT Digital Library
Metagenomic and Functional Analysis of Hindgut Microbiota of a Wood-Feeding Higher Termite (open access)

Metagenomic and Functional Analysis of Hindgut Microbiota of a Wood-Feeding Higher Termite

From the standpoints of both basic research and biotechnology, there is considerable interest in reaching a clearer understanding of the diversity of biological mechanisms employed during lignocellulose degradation. Globally, termites are an extremely successful group of wood-degrading organisms and are therefore important both for their roles in carbon turnover in the environment and as potential sources of biochemical catalysts for efforts aimed at converting wood into biofuels. Only recently have data supported any direct role for the symbiotic bacteria in the gut of the termite in cellulose and xylan hydrolysis. Here we use a metagenomic analysis of the bacterial community resident in the hindgut paunch of a wood-feeding Nasutitermes species to show the presence of a large, diverse set of bacterial genes for cellulose and xylan hydrolysis. Many of these genes were expressed in vivo or had cellulase activity in vitro, and further analyses implicate spirochete and fibrobacter species in gut lignocellulose degradation. New insights into other important symbiotic functions including H{sub 2} metabolism, CO{sub 2}-reductive acetogenesis and N{sub 2} fixation are also provided by this first system-wide gene analysis of a microbial community specialized towards plant lignocellulose degradation. Our results underscore how complex even a 1-{micro}l environment can be.
Date: October 1, 2007
Creator: Warnecke, Falk; Warnecke, Falk; Luginbuhl, Peter; Ivanova, Natalia; Ghassemian, Majid; Richardson, Toby H. et al.
Object Type: Article
System: The UNT Digital Library
Economic Benefits, Carbon Dioxide (CO2) Emissions Reductions, and Water Conservation Benefits from 1,000 Megawatts (MW) of New Wind Power in Wisconsin (Fact Sheet) (open access)

Economic Benefits, Carbon Dioxide (CO2) Emissions Reductions, and Water Conservation Benefits from 1,000 Megawatts (MW) of New Wind Power in Wisconsin (Fact Sheet)

The U.S. Department of Energy?s Wind Powering America Program is committed to educating state-level policymakers and other stakeholders about the economic, CO2 emissions, and water conservation impacts of wind power. This analysis highlights the expected impacts of 1000 MW of wind power in Wisconsin. Although construction and operation of 1000 MW of wind power is a significant effort, six states have already reached the 1000-MW mark. We forecast the cumulative economic benefits from 1000 MW of development in Wisconsin to be $1.1 billion, annual CO2 reductions are estimated at 3.2 million tons, and annual water savings are 1,476 million gallons.
Date: October 1, 2008
Creator: unknown
Object Type: Report
System: The UNT Digital Library
Syntheses, Structure, Magnetism, and Optical Properties of Lutetium-based Interlanthanide Selenides (open access)

Syntheses, Structure, Magnetism, and Optical Properties of Lutetium-based Interlanthanide Selenides

Ln{sub 3}LuSe{sub 6} (Ln = La, Ce), {beta}-LnLuSe{sub 3} (Ln = Pr, Nd), and Ln{sub x}Lu{sub 4-x}Se{sub 6} (Ln = Sm, Gd; x = 1.82, 1.87) have been synthesized using a Sb{sub 2}Se{sub 3} flux at 1000 C. Ln{sub 3}LuSe{sub 6} (Ln = La, Ce) adopt the U{sub 3}ScS{sub 6}-type three-dimensional structure, which is constructed from two-dimensional {infinity}{sup 2} [Ln{sub 3}Se{sub 6}]{sup 3-} slabs with the gaps between these slabs filled by octahedrally coordinated Lu{sup 3+} ions. The series of {beta}-LnLuSe{sub 3} (Ln = Pr, Nd) are isotypic with UFeS{sub 3}. Their structures include layers formed from LuSe6 octahedra that are separated by eight-coordinate larger Ln{sup 3+} ions in bicapped trigonal prismatic environments. Sm{sub 1.82}Lu{sub 2.18}Se{sub 6} and Gd{sub 1.87}Lu{sub 2.13}Se{sub 6} crystallize in the disordered F-Ln{sub 2}S{sub 3} type structure with the eight-coordinate bicapped trigonal prismatic Ln(1) ions residing in the one-dimensional channels formed by three different double chains via edge and corner sharing. These double chains are constructed from Ln(2)Se{sub 7} monocapped trigonal prisms, Ln(3)Se{sub 6} octahedra, and Ln(4)S{sub 6} octahedra, respectively. The magnetic susceptibilities of {beta}-PrLuSe{sub 3} and {beta}-NdLuSe{sub 3} follow the Curie-Weiss law. Sm{sub 1.82}Lu{sub 2.18}Se{sub 6} shows van Vleck paramagnetism. Magnetic measurements show that Gd{sub …
Date: October 1, 2007
Creator: Booth, Corwin H; Jin, Geng Bang; Choi, Eun Sang; Guertin, Robert P.; Brooks, James S.; Booth, Corwin H. et al.
Object Type: Article
System: The UNT Digital Library
Tevatron results on the discovery of sigma^(*)_b, b_s oscillations and the measurement of delta m_s, the lifetime difference delta gamma_s and the cp-violating phase phi (open access)

Tevatron results on the discovery of sigma^(*)_b, b_s oscillations and the measurement of delta m_s, the lifetime difference delta gamma_s and the cp-violating phase phi

The author discusses results from the Tevatron experiments on mixing and CP-violation in B{sub s} mesons, including the observation of B{sub s} oscillations and the first precision measurement of the mixing frequency, as well as a measurement of the lifetime difference {Delta}{Lambda}{sub s} and the first measurement of the CP-violating phase {delta}{sub s}. The author also briefly reports on the observation of four new bottom baryons at CDF.
Date: October 1, 2007
Creator: Heijboer, Aart
Object Type: Article
System: The UNT Digital Library
Idaho National Laboratory Cultural Resource Monitoring Report for Fiscal Year 2007 (open access)

Idaho National Laboratory Cultural Resource Monitoring Report for Fiscal Year 2007

This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year 2007 (FY 2007). In FY 2007, 40 localities were revisited: two locations of heightened Shoshone-Bannock tribal sensitivity, four caves, three butte/craters, twelve prehistoric archaeological sites, two historic stage stations, nine historic homesteads, a portion of Goodale’s Cutoff of the Oregon Trail, a portion of historic trail T-16, one World War II dump, four buildings from the World War II period, and Experimental Breeder Reactor –I, a modern scientific facility and National Historic Landmark. Several INL project areas were also monitored in FY 2007. This included direct observation of ground disturbing activities within the Power Burst Facility (PBF, now designated as the Critical Infrastructure Test Range Complex – CITRC), backfilling operations associated with backhoe trenches along the Big Lost River, and geophysical surveys designed to pinpoint subsurface unexploded ordnance in the vicinity of the Naval Ordnance Disposal Area. Surprise checks were also made to three ongoing INL projects to ensure compliance with INL CRM Office recommendations to avoid impacts to cultural resources. Although some impacts were documented, no significant adverse effects that would threaten the National Register eligibility of …
Date: October 1, 2007
Creator: Pace, Brenda R.
Object Type: Report
System: The UNT Digital Library
Progress In High Temperature Electrolysis At The Idaho National Laboratory (open access)

Progress In High Temperature Electrolysis At The Idaho National Laboratory

The United States is considering the development of a domestic hydrogen-based energy economy. Hydrogen is of particular interest as a secondary energy carrier because it has the potential to be storable, transportable, environmentally benign, and useful in many chemical processes. Obviously, before a hydrogen economy can be implemented, an efficient and environmentally friendly means for large scale hydrogen production must be identified, proven, and developed. Hydrogen is now produced primarily via steam reforming of methane. However, from a long-term perspective, methane reforming is not a viable process for large-scale production of hydrogen since such fossil fuel conversion processes consume non-renewable resources and emit greenhouse gases. The U. S. National Research Council has recommended the use of water-splitting technologies to produce hydrogen using energy derived from a nuclear reactor. For the past several years, the Idaho National Laboratory has been actively studying the use of solid oxide fuel cells in conjunction with nuclear power for large-scale, high-temperature, electrolytic hydrogen production.
Date: October 1, 2007
Creator: Stoots, Carl M.; E.O'Brien, James; Herring, J. Steve & Hartvigsen, Joseph
Object Type: Article
System: The UNT Digital Library
Measuring the maturity of a technology : guidance on assigning a TRL. (open access)

Measuring the maturity of a technology : guidance on assigning a TRL.

This report provides guidance on how to assign a technology readiness level (TRL). The method proposed assists in assigning TRLs through a series of questions that focus on a set of unambiguous maturation metrics. This method is slightly biased towards the environment and approach to technology maturation at Sandia National Laboratories where customers and suppliers are in very close proximity to one another, allowing for supplier-customer interactions at a very early stage in technology development. The hope is that this report can serve as a practical guide to anyone trying to understand the maturity of a specific technology. Risk is reduced in system acquisition by selecting mature technologies for inclusion in system development. TRLs are used to assess the maturity of evolving technologies and therefore become part of an overall risk reduction strategy in system development.
Date: October 1, 2007
Creator: Mitchell, John Anthony
Object Type: Report
System: The UNT Digital Library
Economic Benefits, Carbon Dioxide (CO2) Emissions Reductions, and Water Conservation Benefits from 1,000 Megawatts (MW) of New Wind Power in New Mexico (Fact Sheet) (open access)

Economic Benefits, Carbon Dioxide (CO2) Emissions Reductions, and Water Conservation Benefits from 1,000 Megawatts (MW) of New Wind Power in New Mexico (Fact Sheet)

The U.S. Department of Energy?s Wind Powering America Program is committed to educating state-level policymakers and other stakeholders about the economic, CO2 emissions, and water conservation impacts of wind power. This analysis highlights the expected impacts of 1000 MW of wind power in New Mexico. Although construction and operation of 1000 MW of wind power is a significant effort, six states have already reached the 1000-MW mark. We forecast the cumulative economic benefits from 1000 MW of development in New Mexico to be $1.1 billion, annual CO2 reductions are estimated at 2.6 million tons, and annual water savings are 1,117 million gallons.
Date: October 1, 2008
Creator: unknown
Object Type: Report
System: The UNT Digital Library
Abstract: Air, Thermal and Water Management for PEM Fuel Cell Systems (open access)

Abstract: Air, Thermal and Water Management for PEM Fuel Cell Systems

PEM fuel cells are excellent candidates for transportation applications due to their high efficiencies. PEM fuel cell Balance of Plant (BOP) components, such as air, thermal, and water management sub-systems, can have a significant effect on the overall system performance, but have traditionally not been addressed in research and development efforts. Recognizing this, the U.S. Department of Energy and Honeywell International Inc. are funding an effort that emphasizes the integration and optimization of air, thermal and water management sub-systems. This effort is one of the major elements to assist the fuel cell system developers and original equipment manufacturers to achieve the goal of an affordable and efficient power system for transportation applications. Past work consisted of: (1) Analysis, design, and fabrication of a motor driven turbocompressor. (2) A systematic trade study to select the most promising water and thermal management systems from five different concepts (absorbent wheel humidifier, gas to gas membrane humidifier, porous metal foam humidifier, cathode recycle compressor, and water injection pump.) This presentation will discuss progress made in the research and development of air, water and thermal management sub-systems for PEM fuel cell systems in transportation applications. More specifically, the presentation will discuss: (1) Progress of the …
Date: October 1, 2008
Creator: Mirza, Mark K. Gee Zia
Object Type: Article
System: The UNT Digital Library
A search for z boson pair production at the Fermilab Tevatron Collider (open access)

A search for z boson pair production at the Fermilab Tevatron Collider

This dissertation describes a search for Z/{gamma}* boson pair production decaying into {mu}{mu}{mu}{mu}, {mu}{mu}ee, and eeee final states with approximately 1 fb{sup -1} of data at the Fermilab Tevatron Collider at {radical}s = 1.96 TeV. The small cross section times branching ratio for each channel mandated a thorough study of the acceptance and efficiencies. After optimization, 1.7 {+-} 0.1 events are expected for Standard Model production with a background of 0.13 {+-} 0.03 events. One event was found in the {mu}{mu}ee channel. A cross section limit of 4.4 pb is determined at a 95% confidence level for Standard Model production. Additionally, one parameter and two parameter 95% C.L. limits are found for the anomalous neutral trilinear gauge couplings ZZZ* and ZZ{gamma}*. The one parameter 95% C.L. coupling limits with a form factor scale of 1.2 TeV are: -0.28 < f{sub 40}{sup Z} < 0.28, -0.31 < f{sub 50}{sup Z} < 0.29, -0.26 < f{sub 40}{gamma} < 0.26, and -0.30 < f{sub 50}{sup {gamma}} < 0.28.
Date: October 1, 2007
Creator: Jarvis, Chad Ryan
Object Type: Thesis or Dissertation
System: The UNT Digital Library
Scalable fault tolerant algorithms for linear-scaling coupled-cluster electronic structure methods. (open access)

Scalable fault tolerant algorithms for linear-scaling coupled-cluster electronic structure methods.

By means of coupled-cluster theory, molecular properties can be computed with an accuracy often exceeding that of experiment. The high-degree polynomial scaling of the coupled-cluster method, however, remains a major obstacle in the accurate theoretical treatment of mainstream chemical problems, despite tremendous progress in computer architectures. Although it has long been recognized that this super-linear scaling is non-physical, the development of efficient reduced-scaling algorithms for massively parallel computers has not been realized. We here present a locally correlated, reduced-scaling, massively parallel coupled-cluster algorithm. A sparse data representation for handling distributed, sparse multidimensional arrays has been implemented along with a set of generalized contraction routines capable of handling such arrays. The parallel implementation entails a coarse-grained parallelization, reducing interprocessor communication and distributing the largest data arrays but replicating as many arrays as possible without introducing memory bottlenecks. The performance of the algorithm is illustrated by several series of runs for glycine chains using a Linux cluster with an InfiniBand interconnect.
Date: October 1, 2004
Creator: Leininger, Matthew L.; Nielsen, Ida Marie B. & Janssen, Curtis L.
Object Type: Report
System: The UNT Digital Library
Addendum to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 454: Historical Undrground Storage Tank Release Sites, Nevada Test Site, Nevada, Revision 0 (open access)

Addendum to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 454: Historical Undrground Storage Tank Release Sites, Nevada Test Site, Nevada, Revision 0

This document constitutes an addendum to the April 1998, Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 454: Historical Underground Storage Tank Release Sites as described in the document Recommendations and Justifications for Modifications for Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office Federal Facility Agreement and Consent Order (UR Modification document) dated February 2008. The UR Modification document was approved by NDEP on February 26, 2008. The approval of the UR Modification document constituted approval of each of the recommended UR modifications. In conformance with the UR Modification document, this addendum consists of: • This cover page that refers the reader to the UR Modification document for additional information • The cover and signature pages of the UR Modification document • The NDEP approval letter • The corresponding section of the UR Modification document This addendum provides the documentation justifying the cancellation of the UR for CAS 12-25-09, Spill 960722-02 (from UST 12-B-3). This UR was established as part of a Federal Facility Agreement and Consent Order (FFACO) corrective action and is based on the presence of contaminants at concentrations greater than the action levels established at the …
Date: October 1, 2008
Creator: Kidman, Lynn
Object Type: Report
System: The UNT Digital Library
Current Activities of the ASME Subgroup NUPACK (open access)

Current Activities of the ASME Subgroup NUPACK

Current activities of the American Society of Mechanical Engineers (ASME), Section III Subgroup on Containment Systems for Spent Fuel High-Level Waste Transport Packagings (also known as Subgroup NUPACK) are reviewed with emphasis on the recent revision of Subsection WB. Also, brief insightson new proposals for the development of rules for internal support structures and for a strain-based acceptance criteria are provided.
Date: October 1, 2007
Creator: Foster, Gerald M.; Morton, D. Keith & McConnell, Paul
Object Type: Article
System: The UNT Digital Library
Cell Phone Detection Techniques (open access)

Cell Phone Detection Techniques

A team composed of Rick Pratt, Dave Puczyki, Kyle Bunch, Ryan Slaugh, Morris Good, and Doug McMakin teamed together to attempt to exploit cellular telephone features and detect if a person was carrying a cellular telephone into a Limited Area. The cell phone’s electromagnetic properties were measured, analyzed, and tested in over 10 different ways to determine if an exploitable signature exists. The method that appears to have the most potential for success without adding an external tag is to measure the RF spectrum, not in the cell phone band, but between 240 and 400MHz. Figures 1- 7 show the detected signal levels from cell phones from three different manufacturers.
Date: October 1, 2007
Creator: Pratt, Richard M.; Bunch, Kyle J.; Puzycki, David J.; Slaugh, Ryan W.; Good, Morris S. & McMakin, Douglas L.
Object Type: Report
System: The UNT Digital Library
Modeling the Integrated Performance of Dispersion and Monolithic U-Mo Based Fuels (open access)

Modeling the Integrated Performance of Dispersion and Monolithic U-Mo Based Fuels

The evaluation and prediction of integrated fuel performance is a critical component of the Reduced Enrichment for Research and Test Reactors (RERTR) program. The PLATE code is the primary tool being developed and used to perform these functions. The code is being modified to incorporate the most recent fuel/matrix interaction correlations as they become available for both aluminum and aluminum/silicon matrices. The code is also being adapted to treat cylindrical and square pin geometries to enhance the validation database by including the results gathered from various international partners. Additional modeling work has been initiated to evaluate the thermal and mechanical performance requirements unique to monolithic fuels during irradiation.
Date: October 1, 2006
Creator: Wachs, Daniel M.; Burkes, Douglas E.; Hayes, Steven L.; Moore, Karen; Miller, Greg; Hofman, Gerard et al.
Object Type: Article
System: The UNT Digital Library
Alloys for advanced steam turbines--Oxidation behavior (open access)

Alloys for advanced steam turbines--Oxidation behavior

Advanced or ultra supercritical (USC) steam power plants offer the promise of higher efficiencies and lower emissions. Current goals of the U.S. Department of Energy (DOE) include power generation from coal at 60% efficiency, which would require steam temperatures of up to 760°C. Current research on the oxidation of candidate materials for advanced steam turbines is presented with a focus on a methodology for estimating chromium evaporation rates from protective chromia scales. The high velocities and pressures of advanced steam turbines lead to evaporation predictions as high as 5 × 10-8 kg m-2s-1 of CrO2(OH)2(g) at 760°C and 34.5 MPa. This is equivalent to 0.077 mm per year of solid Cr loss.
Date: October 1, 2007
Creator: Holcomb, G. R.
Object Type: Article
System: The UNT Digital Library
Addendum to the Closure Report for Corrective Action Unit 394: Areas 12, 18, and 29 Spill/Release Sites Nevada Test Site, Nevada, Revision 0 (open access)

Addendum to the Closure Report for Corrective Action Unit 394: Areas 12, 18, and 29 Spill/Release Sites Nevada Test Site, Nevada, Revision 0

This document constitutes an addendum to the September 2003, Closure Report for Corrective Action Unit 394: Areas 12, 18, and 29 Spill/Release Sites as described in the document Recommendations and Justifications for Modifications for Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office Federal Facility Agreement and Consent Order (UR Modification document) dated February 2008. The UR Modification document was approved by NDEP on February 26, 2008. The approval of the UR Modification document constituted approval of each of the recommended UR modifications. In conformance with the UR Modification document, this addendum consists of: • This cover page that refers the reader to the UR Modification document for additional information • The cover and signature pages of the UR Modification document • The NDEP approval letter • The corresponding section of the UR Modification document This addendum provides the documentation justifying the cancellation of the URs for: • CAS 12-25-04, UST 12-16-2 Waste Oil Release • CAS 18-25-01, Oil Spills • CAS 18-25-02, Oil Spills • CAS 18-25-03, Oil Spill • CAS 29-44-01, Fuel Spill These URs were established as part of Federal Facility Agreement and Consent Order (FFACO) corrective actions and were …
Date: October 1, 2008
Creator: Kidman, Lynn
Object Type: Report
System: The UNT Digital Library
In Vivo Characterization of Human APOA5 Haplotypes (open access)

In Vivo Characterization of Human APOA5 Haplotypes

Increased plasma triglycerides concentrations are an independent risk factor for cardiovascular disease. Numerous studies support a reproducible genetic association between two minor haplotypes in the human apolipoprotein A5 gene (APOA5) and increased plasma triglyceride concentrations. We thus sought to investigate the effect of these minor haplotypes (APOA5*2 and APOA5*3) on ApoAV plasma levels through the precise insertion of single-copy intact APOA5 haplotypes at a targeted location in the mouse genome. While we found no difference in the amount of human plasma ApoAV in mice containing the common APOA5*1 and minor APOA5*2 haplotype, the introduction of the single APOA5*3 defining allele (19W) resulted in 3-fold lower ApoAV plasma levels consistent with existing genetic association studies. These results indicate that S19W polymorphism is likely to be functional and explain the strong association of this variant with plasma triglycerides supporting the value of sensitive in vivo assays to define the functional nature of human haplotypes.
Date: October 1, 2006
Creator: Ahituv, Nadav; Akiyama, Jennifer; Chapman-Helleboid, Audrey; Fruchart, Jamila & Pennacchio, Len A.
Object Type: Article
System: The UNT Digital Library