The Human Genome Initiative is a worldwide research effort with the goal of analyzing the structure of human DNA and determining the location of the estimated 100,000 human genes. In parallel with this effort, the DNA of a set of model organisms will be studied to provide the comparative information necessary for understanding the functioning of the human genome. The information generated by the human genome project is expected to be the source book for biomedical science in the 21st century and will by of immense benefit to the field of medicine. It will help us to understand and eventually treat many of the more than 4000 genetic diseases that affect mankind, as well as the many multifactorial diseases in which genetic predisposition plays an important role. A centrally coordinated project focused on specific objectives is believed to be the most efficient and least expensive way of obtaining this information. The basic data produced will be collected in electronic databases that will make the information readily accessible on convenient form to all who need it. This report describes the plans for the U.S. human genome project and updates those originally prepared by the Office of Technology Assessment (OTA) and the …

This report presents a five year plan for the laboratory. This plan takes advantage of the technical strengths of the lab and its staff to address issues of concern to the nation on a scope much broader than Sandia`s original mission, while maintaining the general integrity of the laboratory. The plan proposes initiatives in a number of technologies which overlap the needs of its customers and the strengths of its staff. They include: advanced manufacturing technology; electronics; information and computational technology; transportation energy technology and infrastructure; environmental technology; energy research and technology development; biomedical systems engineering; and post-cold war defense imperatives.

A team of senior managers from across the US Nuclear Regulatory Commission (NRC), working with the Office of Information Resources Management (IRM), has completed an NRC Strategic Information Technology (IT) Plan. The Plan addresses three major areas: (1) IT Program Management, (2) IT Infrastructure, and (3) Information and Applications Management. Key recommendations call for accelerating the replacement of Agency workstations, implementing a new document management system, applying business process reengineering to selected Agency work processes, and establishing an Information Technology Council to advise the Director of IRM.

This is an internal DOE Geothermal Program planning and control document. The Five Year Plans and Multi-Year Plans usually included more detailed rationales and projections than other similar reports. Many of these reports were issued only in draft form. (DJE 2005)

This is an internal DOE Geothermal Program planning and control document. The Five Year Plans and Multi-Year Plans usually included more detailed rationales and projections than other similar reports. Many of these reports were issued only in draft form. (DJE 2005)

This report contains the project summary, as well as the financial summary for the Mixed Waste Management Facility at Lawrence Livermore National Laboratory. Detailed accomplishments and milestone status are reported in the Task Summaries. The major accomplishments during this reporting period are included the following areas: preliminary design; systems integration; briefings for the Environmental Programs Scientific Advisory Committee; integrated cost/scheduling estimating system; feed preparation; mediated electrochemical oxidation; and molten salt oxidation.

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The Buried Waste Integrated Demonstration (BWID) is a program funded by the U.S. Department of Energy Office of Technology Development. BWID supports the applied research, development, demonstration, testing, and evaluation of a suite of advanced technologies that together form a comprehensive remediation system for the effective and efficient remediation of buried waste. The FY-95 effort will fund 24 technologies in five areas of buried waste site remediation: site characterization, waste characterization, retrieval, treatment, and containment/stabilization. Ten of these technologies will take part in the integrated field demonstration that will take place at the Idaho National Engineering Laboratory (INEL) facilities in the summer of 1995. This document is the basic operational planning document for deployment of all BWID projects funded in FY-95. Discussed in this document are the BWID preparations for the INEL integrated field demonstration, INEL research and development (R&D) demonstrations, non-INEL R&D demonstrations, and office research and technical review meetings. Each project will have a test plan detailing the specific procedures, objectives, and tasks of the test. Therefore, information that is specific to testing each technology is intentionally limited in this document.

This report gives the second year`s findings of a study of how thermal and radiological processes may change the composition of organic compounds in the underground tanks at Hanford. Efforts were focused on the global reaction kinetics in a simulated waste exposed to {gamma} rays and the reactions of organic radicals with nitrite ion. The gas production is predominantly radiolytic. Decarboxylation of carboxylates is probably an aging pathway. TBP was totaly consumed in almost every run. Radiation clearly accelerated consumption of the other compounds. EDTA is more reactive than citrate. Oximes and possibly organic nitro compounds are key intermediates in the radiolytic redox reactions of organic compounds with nitrate/nitrite. Observations are consistent with organic compounds being progressively degraded to compounds with greater numbers of C-O bonds and fewer C-H and C-C bonds, resulting in an overall lower energy content. If the radwaste tanks are adequately ventilated and continually dosed by radioactivity, their total energy content should have declined. Level of risk depends on how rapidly carboxylate salts of moderate energy content (including EDTA fragments) degrade to low energy oxalate and formate.

The Department of Energy has consolidated its plans for Information Systems, Computing Resources, and Telecommunications into a single document, the Information Technology Resources Long-Range Plan. The consolidation was done as a joint effort by the Office of ADP Management and the Office of Computer Services and Telecommunications Management under the Deputy Assistant Secretary for Administration, Information, and Facilities Management. This Plan is the product of a long-range planning process used to project both future information technology requirements and the resources necessary to meet those requirements. It encompasses the plans of the various organizational components within the Department and its management and operating contractors over the next 5 fiscal years, 1991 through 1995.

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The purpose of this revision is to update the Line Item Project, 93-L-GFW-152 Functional Design Criteria (FDC) to reflect changes approved in change control M-24-91-6, Engineering Change Notices (ECNs), and expand the scope to include subsurface investigations along with the borehole drilling. This revision improves the ability and effectiveness of maintaining RCRA and Operational groundwater compliance by combining borehole and well drilling with subsurface data gathering objectives. The total projected number of wells to be installed under this project has decreased from 200 and the scope has been broadened to include additional subsurface investigation activities that usually occur simultaneously with most traditional borehole drilling and monitoring well installations. This includes borehole hydrogeologic characterization activities, and vadose monitoring. These activities are required under RCRA 40 CFR 264 and 265 and WAC 173-303 for site characterization, groundwater and vadose assessment and well placement.

The DOE Geothermal Research Program Update reports contain a fair amount of technical detail and management information at the individual project level. DJE 2005

During the past several years, a considerable amount of work has been carried out showing that microbially enhanced oil recovery (MEOR) is promising and the resulting biotechnology may be deliverable. At Brookhaven National Laboratory (BNL), systematic studies have been conducted which dealt with the effects of thermophilic and thermoadapted bacteria on the chemical and physical properties of selected types of crude oils at elevated temperatures and pressures. Current studies indicate that during the biotreatment several chemical and physical properties of crude oils are affected. The oils are (1) emulsified; (2) acidified; (3) there is a qualitative and quantitative change in light and heavy fractions of the crudes; (4) there are chemical changes in fractions containing sulfur compounds; (5) there is an apparent reduction in the concentration of trace metals; and (6) the qualitative and quantitative changes appear to be microbial species dependent; and (7) there is a distinction between biodegraded and biotreated oils. The downstream biotechnological crude oil processing research performed thus far is of laboratory scale and has focused on demonstrating the technical feasibility of downstream processing with different types of biocatalysts under a variety of processing conditions. Quantitative economic analysis is the topic of the present project which …

In FY95, EG and G Energy Measurements, Inc. (EG and G/EM) continued to support efforts to protect endangered species and cultural resources at the Naval Petroleum Reserves in California (NPRC). These efforts are conducted to ensure NPRC compliance with regulations regarding the protection of listed species and cultural resources on Federal properties. Population monitoring activities are conducted annually for San Joaquin kit foxes, giant kangaroo rats, blunt-nosed leopard lizards, and Hoover`s wooly-star. To mitigate impacts of oil field activities on listed species, 674 preactivity surveys covering approximately 211 hectares (521 acres) were conducted in FY95. EG and G/EM also assisted with mitigating effects from third-party projects, primarily by conducting biological and cultural resource consultations with regulatory agencies. EG and G/EM has conducted an applied habitat reclamation program at NPRC since 1985. In FY95, an evaluation of revegetation rates on reclaimed and non-reclaimed disturbed lands was completed, and the results will be used to direct future habitat reclamation efforts at NPRC. In FY95, reclamation success was monitored on 50 sites reclaimed in 1985. An investigation of factors influencing the distribution and abundance of kit foxes at NPRC was initiated in FY94. Factors being examined include habitat disturbance, topography, grazing, coyote abundance, …

The Technical Training Center provides initial and continuing technical training for NRC staff and contractors to satisfy training needs defined by formal NRC staff qualification and training programs. Technical training includes reactor technology programs and specialized technical programs. Reactor technology programs include a spectrum of courses, including classroom and simulator instruction, in each of the four Nuclear Steam Supply System vendor designs--General Electric (GE), Westinghouse, Combustion Engineering (CE), and Babcock and Wilcox (B and W). Specialized technical training includes courses in engineering support, probabilistic risk assessment, radiation protection, fuel cycle technology, safeguards, and regulatory skills. The report presents the activities of the Technical Training Center in FY95 in support of the NRC`s mission.

This is the Fiscal Year 1995 Annual Report for the Advanced Manufacturing Science and Technology (AMST) sector of Los Alamos Tactical Goal 6, Industrial Partnering. During this past fiscal year, the AMST project leader formed a committee whose members represented the divisions and program offices with a manufacturing interest to examine the Laboratory`s expertise and needs in manufacturing. From a list of about two hundred interest areas, the committee selected nineteen of the most pressing needs for weapon manufacturing. Based upon Los Alamos mission requirements and the needs of the weapon manufacturing (Advanced Design and Production Technologies (ADaPT)) program plan and the other tactical goals, the committee selected four of the nineteen areas for strategic planning and possible industrial partnering. The areas selected were Casting Technology, Constitutive Modeling, Non-Destructive Testing and Evaluation, and Polymer Aging and Lifetime Prediction. For each area, the AMST committee formed a team to write a roadmap and serve as a partnering technical consultant. To date, the roadmaps have been completed for each of the four areas. The Casting Technology and Polymer Aging teams are negotiating with specific potential partners now, at the close of the fiscal year. For each focus area we have created a …

Sandia recently completed an updated strategic plan, the essence of which is presented in chapter 4. Sandia`s Strategic Plan 1994 takes its direction from DOE`s Fueling a Competitive Economy: Strategic Plan and provides tangible guidance for Sandia`s programs and operations. Although it is impossible to foresee precisely what activities Sandia will pursue many years from now, the strategic plan makes one point clear: the application of our scientific and engineering skills to the stewardship of the nation`s nuclear deterrent will be central to our service to the nation. We will provide the necessary institutional memory and continuity, experience base, and technical expertise to ensure the continued safety, security, and reliability of the nuclear weapons stockpile. As a multiprogram laboratory, Sandia will also continue to focus maximum effort on a broad spectrum of other topics consistent with DOE`s enduring core mission responsibilities: Defense (related to nuclear weapons), Energy, Environment (related to waste management and environmental remediation), and Basic Science.

The United States Nuclear Regulatory Commission`s Office for Analysis and Evaluation of Operational Data (AEOD) has published reports of its activities since 1984. The first report covered January through June of 1984, and the second report covered July through December 1984. Since those first two semiannual reports, AEOD has published annual reports of its activities from 1985 through 1993. Beginning with the report for 1986, AEOD Annual Reports have been published as NUREG-1272. Beginning with the report for 1987, NUREG-1272 has been published in two parts, No. 1 covering power reactors and No. 2 covering nonreactors (changed to {open_quotes}nuclear materials{close_quotes} with the 1993 report). The 1993 AEOD Annual Report was NUREG-1272, Volume 8. AEOD has changed its annual report from a calendar year to a fiscal year report to be consistent with the NRC Annual Report and to conserve staff resources. NUREG-1272, Volume 9, No. 1 and No. 2, therefore, are combined calendar year 1994 (1994) and fiscal year 1995 (FY 95) reports which describe activities conducted between January 1, 1994, and September 30, 1995. Certain data which have historically been reported on a calendar year basis, however, are complete through calendar year 1995. Throughout this report, whenever information is …

The mission of the Engineering Research, Development, and Technology Program at Lawrence Livermore National Laboratory (LLNL) is to develop the knowledge base, process technologies, specialized equipment, tools and facilities to support current and future LLNL programs. Engineering`s efforts are guided by a strategy that results in dual benefit: first, in support of Department of Energy missions, such as national security through nuclear deterrence; and second, in enhancing the nation`s economic competitiveness through their collaboration with US industry in pursuit of the most cost-effective engineering solutions to LLNL programs. To accomplish this mission, the Engineering Research, Development, and Technology Program has two important goals: (1) identify key technologies relevant to LLNL programs where they can establish unique competencies, and (2) conduct high-quality research and development to enhance their capabilities and establish themselves as the world leaders in these technologies. To focus Engineering`s efforts, technology thrust areas are identified and technical leaders are selected for each area. The thrust areas are comprised of integrated engineering activities, staffed by personnel from the nine electronics and mechanical engineering divisions, and from other LLNL organizations. This annual report, organized by thrust area, describes Engineering`s activities for fiscal year 1995. The report provides timely summaries of …

This annual report of the US Nuclear Regulatory Commission`s Office for Analysis and Evaluation of Operational Data (AEOD) describes activities conducted during CY 1994 and FY 1995. The report is published in three parts. NUREG-1272, Vol. 9, No. 1, covers power reactors and presents an overview of the operating experience of the nuclear power industry from the NRC perspective, including comments about the trends of some key performance measures. The report also includes the principal findings and issues identified in AEOD studies over the past year and summarizes information from such sources as licensee event reports, diagnostic evaluations, and reports to the NRC`s Operations Center. NUREG-1272, Vol. 9, No. 2, covers nuclear materials and presents a review of the events and concerns associated with the use of licensed material in nonreactor applications, such as personnel overexposures and medical misadministrations. Both reports also contain a discussion of the Incident Investigation Team program and summarize both the Incident Investigation Team and Augmented Inspection Team reports. Each volume contains a list of the AEOD reports issued from 1980 through FY 1995. NUREG-1272, Vol. 9, No. 3, covers technical training and presents the activities of the Technical Training Center in support of the NRC`s …

Sandia National Laboratories, New Mexico, conducts the Utility Battery Storage Systems Program, which is sponsored by the U.S. Department of Energy`s Office of Utility Technologies. The goal of this program is to assist industry in developing cost-effective battery systems as a utility resource option by 2000. Sandia is responsible for the engineering analyses, contracted development, and testing of rechargeable batteries and systems for utility energy storage applications. This report details the technical achievements realized during fiscal year 1995.

This document contains the Fiscal Year 1995 Plan for the Mixed Waste Management Facility (MWMF) at Lawrence Livermore National Laboratory. Major objectives to be completed during FY 1995 for the MWMF project are listed and described. This report also contains a budget plan, project task summaries, a milestone control log, and a responsibility assignment matrix for the MWMF project.

The US Department of Energy`s (DOE) Buried Waste Integrated Demonstration (BWID) program, which is now part of the Landfill Stabilization Focus Area (LSFA), supports applied research, development, demonstration, and evaluation of a multitude of advanced technologies dealing with underground radioactive and hazardous waste remediation. These innovative technologies are being developed as part of integrated comprehensive remediation systems for the effective and efficient remediation of buried waste sites throughout the DOE complex. These efforts are identified and coordinated in support of Environmental Restoration (EM-40) and Waste Management (EM-30) needs and objectives. Sponsored by the DOE Office of Technology Development (EM-50), BWID and LSFA work with universities and private industry to develop technologies that are being transferred to the private sector for use nationally and internationally. This report contains the details of the purpose, logic, and methodology used to develop and demonstrate DOE buried waste remediation technologies. It also provides a catalog of technologies and capabilities with development status for potential users. Past FY-92 through FY-94 technology testing, field trials, and demonstrations are summarized. Continuing and new FY-95 technology demonstrations also are described.