Pediatric Drug Research: Food and Drug Administration Should More Efficiently Monitor Inclusion of Minority Children (open access)

Pediatric Drug Research: Food and Drug Administration Should More Efficiently Monitor Inclusion of Minority Children

A letter report issued by the General Accounting Office with an abstract that begins "Drug effectiveness and adverse events can vary between children and adults and among racial and ethnic groups. The Food and Drug Administration (FDA) is authorized under the pediatric exclusivity provision to grant drug sponsors 6 months of additional exclusive marketing rights for conducting clinical drug studies in children. The Best Pharmaceuticals for Children Act of 2002 (BPCA) expanded this provision to require FDA to take into account the adequacy of minority representation in pediatric exclusivity studies. BPCA also directed GAO to evaluate the representation of minorities in such studies. GAO examined the extent to which minority children are represented, whether drugs that treat diseases disproportionately affecting minority groups are studied under the provision, and FDA's monitoring of the representation of minority children in the studies. GAO reviewed related FDA documents, FDA requests for pediatric studies and final study results, and interviewed FDA officials and other experts."
Date: September 26, 2003
Creator: United States. General Accounting Office.
System: The UNT Digital Library
U.N. Peacekeeping: Transition Strategies for Post-Conflict Countries Lack Results-Oriented Measures of Progress (open access)

U.N. Peacekeeping: Transition Strategies for Post-Conflict Countries Lack Results-Oriented Measures of Progress

A letter report issued by the General Accounting Office with an abstract that begins "The United Nations responded to the failure of some past peacekeeping operations by developing a strategy to help peacekeeping operations move a country from conflict to sustainable peace. It has attempted to apply this strategy to the large and costly peacekeeping operations in Sierra Leone, East Timor, and the Democratic Republic of the Congo since 2001. As a contributor of over 25 percent of the cost of U.N. operations, the United States has a stake in the successful application of this strategy. The strategy also has implications for the conduct of international peace operations in other post-conflict countries. GAO was asked to (1) identify the elements of the U.N. transition strategy; (2) assess the extent to which the United Nations has applied the strategy to operations; and (3) assess the challenges to implementing the strategy in these three countries."
Date: September 26, 2003
Creator: United States. General Accounting Office.
System: The UNT Digital Library
Postal Pension Funding Reform: Issues Related to the Postal Service's Proposed Use of Pension Savings (open access)

Postal Pension Funding Reform: Issues Related to the Postal Service's Proposed Use of Pension Savings

A letter report issued by the General Accounting Office with an abstract that begins "In April 2003, Congress enacted the Postal Civil Service Retirement System (CSRS) Funding Reform Act of 2003 (P.L. 108-18), which\ lowered the Postal Service's (Service) annual payment for its CSRS obligation by over $2.5 billion beginning in fiscal year 2003. P.L. 108-18 includes requiring (1) the Service to begin making payments into an escrow account in fiscal year 2006, (2) the Service to issue a report on its proposed use of "savings" resulting from the lower CSRS payments, and (3) GAO to evaluate the Service's report and present its findings to Congress. GAO evaluated whether the Service's proposals were consistent with P.L. 108-18; the impact of the escrow account; and whether the proposals were fair to current and future ratepayers, affordable, and helped achieve transformation goals."
Date: November 26, 2003
Creator: United States. General Accounting Office.
System: The UNT Digital Library
Pesticides on Tobacco: Federal Activities to Assess Risks and Monitor Residues (open access)

Pesticides on Tobacco: Federal Activities to Assess Risks and Monitor Residues

A letter report issued by the General Accounting Office with an abstract that begins "Pesticides play a significant role in increasing production of tobacco, food, and other crops by reducing the number of crop-destroying pests. However, if used improperly, pesticides can have significant adverse health effects. GAO was asked to (1) identify the pesticides commonly used on tobacco crops and the potential health risks associated with them, (2) determine how the Environmental Protection Agency (EPA) assesses and mitigates health risks associated with pesticides used on tobacco, and (3) assess the extent to which federal agencies regulate and test for pesticide residues on tobacco."
Date: March 26, 2003
Creator: United States. General Accounting Office.
System: The UNT Digital Library
International Trade: Experts' Advice for Small Businesses Seeking Foreign Patents (open access)

International Trade: Experts' Advice for Small Businesses Seeking Foreign Patents

A letter report issued by the General Accounting Office with an abstract that begins "Small businesses, which are important to the U.S. economy for their roles in job creation and technological development, must be able to protect and profit from their innovations. One way to protect their innovations on a global basis is to obtain U.S. and foreign patents. These businesses, however, face numerous impediments when trying to patent their goods or processes abroad. These impediments, which GAO identified in a July 2002 report, include high costs, limited resources, and limited knowledge among small businesses about foreign patent laws and systems. Because of concern that small businesses, particularly high technology firms, were not obtaining patent protection abroad and thus were losing potential sales in foreign markets, GAO was asked to (1) identify the factors that patent law experts believe small businesses should consider as they decide whether to seek patent protection abroad and provide information on how small businesses viewed these factors and (2) identify the steps that small businesses should take to improve their foreign patent efforts, according to our survey of patent law experts."
Date: June 26, 2003
Creator: United States. General Accounting Office.
System: The UNT Digital Library
Postal Pension Funding Reform: Review of Military Service Funding Proposals (open access)

Postal Pension Funding Reform: Review of Military Service Funding Proposals

A letter report issued by the General Accounting Office with an abstract that begins "The Postal Civil Service Retirement System Funding Reform Act of 2003 (the Act) required the United States Postal Service, Department of the Treasury, and Office of Personnel Management (OPM) to prepare proposals detailing whether and to what extent the Treasury and Postal Service should fund the benefits attributable to the military service of the Postal Service's current and former Civil Service Retirement System (CSRS) employees. The Act required GAO to evaluate the proposals. Our objective in doing so was to assess the agencies' positions and provide additional information where it may be useful."
Date: November 26, 2003
Creator: United States. General Accounting Office.
System: The UNT Digital Library
Environmental Protection Agency: Continued Improvement Needed in Assessing Equal Employment Opportunity (open access)

Environmental Protection Agency: Continued Improvement Needed in Assessing Equal Employment Opportunity

A letter report issued by the General Accounting Office with an abstract that begins "Minority employees at the EPA reported for a number of years that the agency had discriminated against them based on their race and retaliated against them for filing complaints. These issues were aired at hearings held by the House Committee on Science at which EPA said it would take actions to ensure a fair and discrimination free workplace. GAO was asked to review (1) the accuracy of EPA's equal employment opportunity (EEO) data, (2) various issues about the processes used to resolve discrimination complaints, and (3) the disciplinary actions taken for managers who discriminate."
Date: June 26, 2003
Creator: United States. General Accounting Office.
System: The UNT Digital Library
Combating Money Laundering: Opportunities Exist to Improve the National Strategy (open access)

Combating Money Laundering: Opportunities Exist to Improve the National Strategy

A letter report issued by the General Accounting Office with an abstract that begins "Money laundering is a serious crime, with hundreds of billions of dollars laundered annually. Congress passed the Money Laundering and Financial Crimes Strategy Act of 1998 to better coordinate the efforts of law enforcement agencies and financial regulators in combating money laundering. This act required the issuance of an annual National Money Laundering Strategy for 5 years, ending with the issuance of the 2003 strategy. To help with deliberations on reauthorization, GAO determined (1) agency perspectives on the benefit of the strategy and factors that affected its development and implementation, (2) whether the strategy has served as a useful mechanism for guiding the coordination of federal law enforcement agencies' efforts, (3) the role of the strategy in influencing the activities of federal financial regulators, and (4) whether the strategy has reflected key critical components."
Date: September 26, 2003
Creator: United States. General Accounting Office.
System: The UNT Digital Library