The present investigation examined the relationship between elated and depressed moods and dissociation, association, and positive self-talk strategies on endurance performance. Results showed a significant mood main effect with elated subjects performing longer than depressed subjects. Results also revealed a significant cognitive strategy main effect with positive self-talk and dissociation groups producing longer endurance times than association and control groups. A significant interaction between mood and cognitive strategy found that subjects in the positive self-talk and dissociation groups increased their performance time to a greater extent from the depressed to the elated condition than did subjects in the association and control groups. Results are discussed in terms of previous investigations of mood and cognitive strategies on physical performance.