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NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner
This article's study endeavors to determine if p53 is responsible for cisplatin sensitization by NSC109268. Results have implications for sensitivity of ovarian cancer cells to cisplatin independent of p53.
Date:
October 5, 2010
Creator:
Shankar, Eswar; Basu, Chandreyi; Adkins, Brett; Siede, Wolfram & Basu, Alakananda
System:
The UNT Digital Library
Single actomyosin motor interactions in skeletal muscle
This article presents a study of intramuscular motion during contraction of skeletal muscle myofibrils.
Date:
February 21, 2011
Creator:
Földes-Papp, Zeno; Liao, Jeff Shih-Chu; Barbieri, Ben; Grycznski, Karol G.; Luchowski, Rafal; Gryczynski, Ignacy et al.
System:
The UNT Digital Library
Regulation of Autophagy by Kinases
This review focuses on the regulation of autophagy by several kinases with particular emphasis on serine/threonine protein kinases such as mTOR, AMP-activated kinase, Akt, mitogen-activated protein kinase (ERK, p38 and JNK) and protein kinase C that are often deregulated in cancer and are important therapeutic targets.
Date:
June 9, 2011
Creator:
Sridharan, Savitha; Jain, Kirti & Basu, Alakananda
System:
The UNT Digital Library