Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research (open access)

Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research

This review aims to find effective phytoconstituents in cataract treatments in vitro, ex vivo, and in vivo. Scientists have focused their attention not only for anti-cataract activity in vitro, but also in ex vivo and in vivo from the review of active phytoconstituents in medicinal plants. In our present review, we identified 58 active phytoconstituents with strong anti-cataract effects at in vitro and ex vivo with lack of in vivo studies.
Date: October 26, 2018
Creator: Lim, Vuanghao; Schneider, Edward; Wu, Hongli & Pang, Iok-Hou
System: The UNT Digital Library
Lipopolysaccharide Challenge Reveals Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Murine Systemic Lupus Erythematosus (open access)

Lipopolysaccharide Challenge Reveals Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Murine Systemic Lupus Erythematosus

Study explores whether chronic inflammatory processes in systemic lupus erythematosus (SLE) are in part due to hypothalamic-pituitary-adrenal (HPA) axis dysfunction by challenging female control and SLE mice with lipopolysaccharide (LPS) and measuring c-Fos expression as an index of neuronal activation, plasma adrenocorticotrophic hormone (ACTH) as an index of anterior pituitary function, and plasma corticosterone as an index of adrenal function.
Date: October 4, 2018
Creator: Pham, Grace S. & Mathis, Keisa W.
System: The UNT Digital Library
NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner (open access)

NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner

This article's study endeavors to determine if p53 is responsible for cisplatin sensitization by NSC109268. Results have implications for sensitivity of ovarian cancer cells to cisplatin independent of p53.
Date: October 5, 2010
Creator: Shankar, Eswar; Basu, Chandreyi; Adkins, Brett; Siede, Wolfram & Basu, Alakananda
System: The UNT Digital Library
Tetracycline-Containing MCM-41 Mesoporous Silica Nanoparticles for the Treatment of Escherichia coli (open access)

Tetracycline-Containing MCM-41 Mesoporous Silica Nanoparticles for the Treatment of Escherichia coli

Paper describes study testing the effectiveness of tetracycline (TC) in mobile crystalline material 41 (MCM-41) for controlled drug release.
Date: October 30, 2019
Creator: Koneru, Bhuvaneswari; Shi, Yi; Wang, Yu-Chieh; Chavala, Sai H.; Miller, Michael L.; Holbert, Brittany et al.
System: The UNT Digital Library
“Youth Are More Aware and Intelligent than Imagined”: The Mountain Air Youth Photovoice Project (open access)

“Youth Are More Aware and Intelligent than Imagined”: The Mountain Air Youth Photovoice Project

This article looks at respiratory illness in Appalachian Kentucky because it reports some of the highest rates of respiratory illness in the United States. As part of the Mountain Air Project, local youth were invited to share their perspectives on possible contributing factors to respiratory illness, and the authors undertook an exploratory study to determine the utility of photovoice to elicit such perspectives with this population. This study demonstrates the value of incorporating youth perspectives in environmental health research, and that photovoice was a valuable approach to elicit such perspectives.
Date: October 11, 2019
Creator: Cardarelli, Katheryn M.; Paul, Marcy; May, Beverly; Dunfee, Madeline; Browning, Steven & Schoenberg, Nancy
System: The UNT Digital Library