17β-Estradiol Delivered in Eye Drops: Evidence of Impact on Protein Networks and Associated Biological Processes in the Rat Retina through Quantitative Proteomics (open access)

17β-Estradiol Delivered in Eye Drops: Evidence of Impact on Protein Networks and Associated Biological Processes in the Rat Retina through Quantitative Proteomics

Study analyzes target engagements through the identification of functional protein networks impacted after delivery of 17β-estradiol in eye drops to facilitate the development of broad-spectrum retina neuroprotectants that can be delivered through topical dosage forms.
Date: January 27, 2020
Creator: Prókai, László, 1958-; Zaman, Khadiza; Nguyen, Vien & Prokai-Tatrai, Katalin
System: The UNT Digital Library
Association of Home Food Availability with Prediabetes and Diabetes among Adults in the United States (open access)

Association of Home Food Availability with Prediabetes and Diabetes among Adults in the United States

This article examined associations of home food availabilities with prediabetes and diabetes among 8929 adults (20–70 years) participating in 2007–2010 National Health and Nutrition Examination Surveys. The results show prediabetes participants had lower availability of healthy foods and higher availability of unhealthy foods, suggesting the need to improve healthy food availability at home for this population.
Date: April 25, 2020
Creator: McAtee, Jenniffer; Tao, Meng-Hua; King, Christian & Chai, Weiwen
System: The UNT Digital Library
Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer (open access)

Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer

The purpose of this article is to compare and contrast the expression, structure, regulation and function of these two S6K homologs in breast cancer.
Date: February 11, 2020
Creator: Sridharan, Savitha & Basu, Alakananda
System: The UNT Digital Library
Intermittent Hypoxic Conditioning Alleviates Post-Traumatic Stress Disorder-Induced Damage and Dysfunction of Rat Visceral Organs and Brain (open access)

Intermittent Hypoxic Conditioning Alleviates Post-Traumatic Stress Disorder-Induced Damage and Dysfunction of Rat Visceral Organs and Brain

Study examines intermittent hypoxic conditioning's (IHC) ability to alleviate harmful PTSD effects on a rat's heart, liver, and brain.
Date: January 5, 2020
Creator: Manukhina, Eugenia B.; Tseilikman, Vadim E.; Karpenko, Marina N.; Pestereva, Nina S.; Tseilikman, Olga B.; Komelkova, Maria V. et al.
System: The UNT Digital Library
Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice (open access)

Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice

Study investigated the role of the neuroprotective kynurenic acid (KYNA) in RGC death against retinal ischemia/reperfusion (I/R) injury.
Date: March 5, 2020
Creator: Nahomi, Rooban B.; Nam, Mi-Hyun; Rankenberg, Johanna; Rakete, Stefan; Houck, Julie A.; Johnson, Ginger C. et al.
System: The UNT Digital Library
Peripheral Circulating Exosomal miRNAs Potentially Contribute to the Regulation of Molecular Signaling Networks in Aging (open access)

Peripheral Circulating Exosomal miRNAs Potentially Contribute to the Regulation of Molecular Signaling Networks in Aging

This article aims to understand some of the causes of aging and the underlying mechanisms that may lead to interventions that could reverse certain aging processes and slow development of aging-related diseases. People are living longer than ever. Consequently, they have a greater chance for developing a functional impairment or aging-related disease, such as a neurodegenerative disease, later in life.
Date: March 11, 2020
Creator: Zhang, Hongxia & Jin, Kunlin
System: The UNT Digital Library
Thymus Functionality Needs More Than a Few TECs (open access)

Thymus Functionality Needs More Than a Few TECs

Article is a review exploring the contributions of the many stromal cell types participating in the formation, expansion, and contraction of the thymus under normal and pathophysiological processes. Such information will better inform approaches for restoring thymus functionality, including thymus organoid technologies, beneficial when an individuals’ own tissue is congenitally, clinically, or accidentally rendered non-functional.
Date: June 10, 2022
Creator: Bhalla, Pratibha; Su, Dong-Ming & van Oers, Nicolai S. C.
System: The UNT Digital Library
Traditional Chinese Medicine and Western Medicine Share Similar Philosophical Approaches to Fight COVID-19 (open access)

Traditional Chinese Medicine and Western Medicine Share Similar Philosophical Approaches to Fight COVID-19

This article is a commentary exploring the disciplines of Western medicine and Traditional Chinese Medicine's philosophical methods to fight COVID-19 to understand their philosophical theories that could achieve the maximum benefits for treatment of COVID-19 and other diseases.
Date: August 1, 2021
Creator: Zhao, Fangfang; Yang, Zhenhong; Wang, Ningqun; Jin, Kunlin & Luo, Yumin
System: The UNT Digital Library