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Adjustment for Local Ancestry in Genetic Association Analysis of Admixed Populations captions transcript

Adjustment for Local Ancestry in Genetic Association Analysis of Admixed Populations

Presentation on the consideration of local ancestry of admixed populations, or populations comprised of genetically distinct ancestral populations which can alter their gene flow in unique ways. It was presented at the UNT Transdisciplinary Conference on Ancestral Genomics Research which was held virtually on November 20-21, 2020.
Date: November 21, 2020
Creator: Wang, Xuexia
Object Type: Video
System: The UNT Digital Library
Approximation Theory and Complex Dynamics (open access)

Approximation Theory and Complex Dynamics

Data management plan for the grant, "Approximation Theory and Complex Dynamics." This project involves the study of approximation theory in the setting of complex functions, with applications to complex dynamics. Approximation theory seeks to understand the extent to which the behavior of a general function can be effectively modeled by that of functions drawn from a more restricted class. Efficient approximation of functions is of relevance for numerical calculation. Since the only calculations that can be carried out numerically are the elementary operations of addition, subtraction, multiplication, and division, in practical terms it is of importance to understand when the values of general functions are well approximated by the values of either polynomial or rational functions. In many situations, the values of the approximant resemble those of the general function only for a sampling of input values. What can be said about values of the approximant for other choices of input? This is the main question studied in this project, with the following application in mind: when a general function is iterated to produce a dynamical system, to what extent does the dynamical behavior of an approximant resemble the dynamical behavior of the original function? The project will also contribute …
Date: 2023-09-01/2026-08-31
Creator: Lazebnik, Kirill
Object Type: Text
System: The UNT Digital Library
Collaborative Research: Conference: Texas-Oklahoma Representations and Automorphic forms (TORA) (open access)

Collaborative Research: Conference: Texas-Oklahoma Representations and Automorphic forms (TORA)

Data management plan for the grant, "Collaborative Research: Conference: Texas-Oklahoma Representations and Automorphic forms (TORA)."
Date: 2024-01-01/2026-12-31
Creator: Beneish, Lea
Object Type: Text
System: The UNT Digital Library
Collaborative Research: Using Uncertainty Quantification and Validated Computational Models to Analyze Pumping Performance of Valveless, Tubular Hearts (open access)

Collaborative Research: Using Uncertainty Quantification and Validated Computational Models to Analyze Pumping Performance of Valveless, Tubular Hearts

Data management plan for the research grant, "Collaborative Research: Using Uncertainty Quantification and Validated Computational Models to Analyze Pumping Performance of Valveless, Tubular Hearts." This project will develop a computational model of the essential features of the circulatory system: the electrical activity of the heart, muscle contractions of the tube walls, and the fluid-structure interactions of the heart walls and blood within. This computational framework aims to be faithful to that of a real, model animal (tunicate, or sea squirt). The model will then be analyzed with mathematical tools to determine the physical limits of the pumping system. Results of this project will improve the understanding of human heart development at the earliest stages. Also, it will point to how the large, multi-chambered hearts of vertebrates could have evolved from smaller structures.
Date: 2022-05-01/2025-04-30
Creator: He, Yanyan & Cain, John
Object Type: Text
System: The UNT Digital Library
Conference: Dynamical Systems and Fractal Geometry (open access)

Conference: Dynamical Systems and Fractal Geometry

Data management plan for the grant, "Conference: Dynamical Systems and Fractal Geometry."
Date: 2024-04-15/2025-03-31
Creator: Allaart, Pieter C.
Object Type: Text
System: The UNT Digital Library
Dense Locally Finite Subgroups of Automorphism Groups of Ultraextensive Spaces (open access)

Dense Locally Finite Subgroups of Automorphism Groups of Ultraextensive Spaces

Article verifying a conjecture of Vershik by showing that Hall’s universal countable locally finite group can be embedded as a dense subgroup in the isometry group of the Urysohn space and in the automorphism group of the random graph. It shows the same for all automorphism groups of known infinite ultraextensive spaces.
Date: August 18, 2021
Creator: Etedadialiabadi, Mahmood; Gao, Su; Le Maître, François & Melleray, Julien
Object Type: Article
System: The UNT Digital Library
Descriptive Complexity in Cantor Series (open access)

Descriptive Complexity in Cantor Series

Article discusses how a Cantor series expansion for a real number x with respect to a basic sequence Q=(q), where qi≥2, is a generalization of the base b expansion to an infinite sequence of bases. The authors show that for any basic sequence the set of distribution normal numbers is Π03-complete, and if Q is 1-divergent then the sets of normal and ratio normal numbers are Π03-complete.
Date: September 27, 2021
Creator: Airey, Dylan; Jackson, Steve & Mance, Bill
Object Type: Article
System: The UNT Digital Library
Duals of Tirilman spaces have unique subsymmetric basic sequences (open access)

Duals of Tirilman spaces have unique subsymmetric basic sequences

Article describes how the Tirilman spaces were introduced by Casazza and Shura as variations of the spaces constructed by Tzafriri. We prove that all subsymmetric basic sequences in the dual space are equivalent to its canonical subsymmetic but not symmetric basis.
Date: September 5, 2023
Creator: Dilworth, Steven J.; Kutzarova, Denka; Sari, Bünyamin & Stankov, Svetozar
Object Type: Article
System: The UNT Digital Library
Estimating Hausdorff measure for Denjoy maps (open access)

Estimating Hausdorff measure for Denjoy maps

Article describes how the authors plant to deal with orientation preserving homeomorphisms and, more specifically, diffeomorphisms of the unit circle S1. By employing the recurrence method worked out in Pawelec the authors provide effective lower estimates of the proper-dimensional Hausdorff measure of minimal sets of circle homeomorphisms that are not conjugate to any rotation.
Date: October 20, 2023
Creator: Pawelec, Łukasz & Urbański, Mariusz
Object Type: Article
System: The UNT Digital Library
The exact consistency strength of the generic absoluteness for the universally Baire sets (open access)

The exact consistency strength of the generic absoluteness for the universally Baire sets

Article describes how a set of reals is universally Baire if all of its continuous preimages in topological spaces have the Baire property. The authors show that over some mild large cardinal theory, sealing is equiconsistent with LSA-over-uB.
Date: January 18, 2023
Creator: Sargsyan, Grigor & Trang, Nam
Object Type: Article
System: The UNT Digital Library
Existence and nonexistence of radial solutions for semilinear equations with bounded nonlinearities on exterior domains (open access)

Existence and nonexistence of radial solutions for semilinear equations with bounded nonlinearities on exterior domains

Article studies radial solutions of ∆u + K(r)f(u) = 0 on the exterior of the ball of radius R > 0 centered at the origin in ℝᶰ where f is odd with f < 0 on (0, β), f > 0 on (β, δ), f ≡ 0 for u > δ, and where the function K(r) is assumed to be positive and K(r) → 0 as r → ∞.
Date: December 1, 2020
Creator: Iaia, Joseph A.
Object Type: Article
System: The UNT Digital Library
Existence of solutions for semilinear problems on exterior domains (open access)

Existence of solutions for semilinear problems on exterior domains

Article proves the existence of an infinite number of radial solutions to ∆u+K(r)f(u) = 0 on ℝᶰ such that limᵣ →∞ u(r) = 0 with prescribed number of zeros on the exterior of the ball of radius R > 0 where f is odd with f < 0 on (0, β), f > 0 on (β, ∞) with f superlinear for large u, and K(r) ∼ r ⁻ᵅ with α > 2(N − 1).
Date: April 15, 2020
Creator: Iaia, Joseph A.
Object Type: Article
System: The UNT Digital Library
Gene-based association tests using GWAS summary statistics and incorporating eQTL (open access)

Gene-based association tests using GWAS summary statistics and incorporating eQTL

Article proposes a powerful and computationally efficient gene-based association test, called Overall. Using extended Simes procedure, Overall aggregates information from three types of traditional gene-based association tests and also incorporates expression quantitative trait locus (eQTL) information into a gene-based association test using GWAS summary statistics. The results show that this newly developed method can identify more significant genes than other methods.
Date: March 3, 2022
Creator: Cao, Xuwei; Wang, Xuexia; Zhang, Shuanglin & Sha, Qiuying
Object Type: Article
System: The UNT Digital Library
A gene based combination test using GWAS summary data (open access)

A gene based combination test using GWAS summary data

Article describes how gene-based association tests provide a useful alternative and complement to the usual single marker association tests, especially in genome-wide association studies (GWAS). The authors propose a test named OWC based on summary statistics from GWAS data.
Date: January 3, 2023
Creator: Zhang, Jianjun; Liang, Xiaoyu; Gonzales, Samantha; Liu, Jianguo; Gao, Xiaoyi Raymond & Wang, Xuexia
Object Type: Article
System: The UNT Digital Library
Gene-Level Analysis of Anthracycline-Induced Cardiomyopathy in Cancer Survivors (open access)

Gene-Level Analysis of Anthracycline-Induced Cardiomyopathy in Cancer Survivors

Article describes how anthracyclines are highly effective in treating cancer, despite increased risk of cardiomyopathy. This study examined gene-level associations with cardiomyopathy among cancer survivors using whole-exome sequencing data.
Date: September 12, 2023
Creator: Sharafeldin, Noha; Zhou, Liting; Singh, Purnima; Crossman, David K.; Wang, Xuexia; Hagerman, Lindsey et al.
Object Type: Article
System: The UNT Digital Library
The genome of jojoba (Simmondsia chinensis): A taxonomically isolated species that directs wax ester accumulation in its seeds (open access)

The genome of jojoba (Simmondsia chinensis): A taxonomically isolated species that directs wax ester accumulation in its seeds

Article describes the high-quality, 887-Mb genome of jojoba assembled into 26 chromosomes with 23,490 protein-coding genes.
Date: March 11, 2020
Creator: Sturtevant, Drew; Lu, Shaoping; Zhou, Zhi-Wei; Shen, Yin; Wang, Shuo; Song, Jia-Ming et al.
Object Type: Article
System: The UNT Digital Library
Haptoglobin Gene Expression and Anthracycline-Related Cardiomyopathy in Childhood Cancer Survivors: A COG-ALTE03N1 Report (open access)

Haptoglobin Gene Expression and Anthracycline-Related Cardiomyopathy in Childhood Cancer Survivors: A COG-ALTE03N1 Report

Article describes how anthracycline-related cardiomyopathy is a leading cause of premature death in childhood cancer survivors. The authors interrogated differentially expressed genes (DEGs) to identify genetic variants serving regulatory functions or genetic variants not easily identified when using genomewide array platforms.
Date: February 7, 2023
Creator: Singh, Purnima; Crossman, David K.; Zhou, Liting; Wang, Xuexia; Sharafeldin, Noha; Hageman, Lindsey et al.
Object Type: Article
System: The UNT Digital Library
Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings (open access)

Lipophilic signals lead to organ-specific gene expression changes in Arabidopsis seedlings

Article presents a study where whole transcriptome sequencing (RNA-seq) and differential expression analysis were used to identify early (1–3 hr) transcriptional changes induced by the exogenous treatment of NAE 18:2 and NAE 18:3 in cotyledons, roots, and seedlings.
Date: July 15, 2020
Creator: Cannon, Ashley E.; Yan, Chengshi; Burks, David J.; Rao, Xiaolan; Azad, Rajeev K. & Chapman, Kent Dean
Object Type: Article
System: The UNT Digital Library
Model checking via testing for direct effects in Mendelian Randomization and transcriptome-wide association studies (open access)

Model checking via testing for direct effects in Mendelian Randomization and transcriptome-wide association studies

This article proposes a new and general goodness-of-fit (GOF) test, called TEDE (TEsting Direct Effects), applicable to both correlated and independent SNPs/IVs as commonly used in transcriptome-wide association studies (TWAS) and Mendelian randomization (MR) respectively.
Date: August 2, 2021
Creator: Deng, Yangqing & Pan, Wei
Object Type: Article
System: The UNT Digital Library
MYB30 Orchestrates Systemic Reactive Oxygen Signaling and Plant Acclimation (open access)

MYB30 Orchestrates Systemic Reactive Oxygen Signaling and Plant Acclimation

This article explores the relationship among MYB30, the ROS wave, and systemic acclimation in Arabidopsis by determining the SAA response to HL stress of MYB30 mutants and wild-type plants.
Date: July 22, 2020
Creator: Fichman, Yosef; Zandalinas, Sara I.; Sengupta, Soham; Burks, David J.; Meyers, Ronald J., Jr.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Nematic order on a deformable vesicle with anchoring effects (open access)

Nematic order on a deformable vesicle with anchoring effects

This article proposes a new model to represent a vesicle membrane with internal nematic order whose equilibrium states depend on the competition between the bending, elastic and anchoring energies.
Date: July 7, 2020
Creator: Tierra Chica, Giordano; Guillén-González, Francisco & Rodríguez-Bellido, María Ángeles
Object Type: Article
System: The UNT Digital Library
On counting cuspidal automorphic representations for GSp(4) (open access)

On counting cuspidal automorphic representations for GSp(4)

Article
Date: April 15, 2021
Creator: Roy, Manami; Schmidt, Ralf & Yi, Shaoyun
Object Type: Article
System: The UNT Digital Library
On Polish groups admitting non-essentially countable actions (open access)

On Polish groups admitting non-essentially countable actions

Article addresses the question whether every Polish group that is not locally compact admits a Borel action on a standard Borel space whose associated orbit equivalence relation is not essentially countable. The authors e answer this question positively for the class of all Polish groups that embed in the isometry group of a locally compact metric space.
Date: September 17, 2019
Creator: Kechris, Alexander S.; Malicki, Maciej; Panagiotopoulos, Aristotelis & Zielinski, Joseph
Object Type: Article
System: The UNT Digital Library
On the standard L-function for GSp2n × GL1 and algebraicity of symmetric fourth L-values for GL2 (open access)

On the standard L-function for GSp2n × GL1 and algebraicity of symmetric fourth L-values for GL2

This article proves an explicit integral representation—involving the pullback of a suitable Siegel Eisenstein series—for the twisted standard L-function associated to a holomorphic vector-valued Siegel cusp form of degree n and arbitrary level.
Date: May 6, 2020
Creator: Pitale, Ameya; Saha, Abhishek & Schmidt, Ralf
Object Type: Article
System: The UNT Digital Library