Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers (open access)

Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers

This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.
Date: May 27, 2011
Creator: Roner, Michael R.; Carraher, Charles E., Jr.; Shahi, Kimberly & Barot, Girish
System: The UNT Digital Library
Use of prior odds for missing persons identifications (open access)

Use of prior odds for missing persons identifications

This article discusses the use of DNA typing, likelihood ratios, and prior odds for missing persons identifications.
Date: June 27, 2011
Creator: Budowle, Bruce; Ge, Jianye; Chakraborty, Ranajit & Gill-King, Harrell
System: The UNT Digital Library
Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals (open access)

Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals

Article evaluating the response to the pharmacological compounds Fluoxetine, Muscimol, and Verapamil in primary neuronal cultures. Final conclusions are drawn that MEA technology has a potential for standard in vitro neurotoxicity/neuropharmacology evaluation.
Date: April 27, 2011
Creator: Novellino, A.; Scelfo, Bibiana; Palosaari, T.; Price, A.; Sobanski, Tomasz; Shafer, T.J. et al.
System: The UNT Digital Library