The report describes the activities and plans of the Climate Change Science Program (CCSP), which incorporates the U.S. Global Change Research Program established under the Global Change Research Act of 1990, and the Climate Change Research Initiative that was established by the President in 2001. CCSP coordinates and integrates scientific research on climate and global change supported by 13 participating departments and agencies of the U.S. Government. The document highlights recent advances and progress supported by CCSP-participating agencies in each of the program's research and observational elements, as called for in the Strategic Plan for the U.S. Climate Change Science Program released in July 2003, and later modified in the 2008 CCSP Revised Research Plan. The document also describes how observational and predictive capabilities are being improved and used to create tools to support decisionmaking at local, regional, and national scales to cope with environmental variability and change.