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Disaster Recovery: Past Experiences Offer Insights for Recovering from Hurricanes Ike and Gustav and Other Recent Natural Disasters (open access)

Disaster Recovery: Past Experiences Offer Insights for Recovering from Hurricanes Ike and Gustav and Other Recent Natural Disasters

A letter report issued by the Government Accountability Office with an abstract that begins "This month, Hurricanes Ike and Gustav struck the Gulf Coast producing widespread damage and leading to federal major disaster declarations. Earlier this year, heavy flooding resulted in similar declarations in seven Midwest states. In response, federal agencies have provided millions of dollars in assistance to help with short- and long-term recovery. State and local governments bear the primary responsibility for recovery and have a great stake in its success. Experiences from past disasters may help them better prepare for the challenges of managing and implementing the complexities of disaster recovery. GAO was asked to identify insights from past disasters and share them with state and local officials undertaking recovery activities. GAO reviewed six past disasters-- the Loma Prieta earthquake in northern California (1989), Hurricane Andrew in south Florida (1992), the Northridge earthquake in Los Angeles, California (1994), the Kobe earthquake in Japan (1995), the Grand Forks/Red River flood in North Dakota and Minnesota (1997), and Hurricanes Katrina and Rita in the Gulf Coast (2005). GAO interviewed officials involved in the recovery from these disasters and experts on disaster recovery. GAO also reviewed relevant legislation, policies, and …
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Nuclear Waste: Action Needed to Improve Accountability and Management of DOE's Major Cleanup Projects (open access)

Nuclear Waste: Action Needed to Improve Accountability and Management of DOE's Major Cleanup Projects

A letter report issued by the Government Accountability Office with an abstract that begins "The Department of Energy (DOE) spends billions of dollars annually to clean up nuclear wastes at sites that produced nuclear weapons. Cleanup projects decontaminate and demolish buildings, remove and dispose of contaminated soil, treat contaminated groundwater, and stabilize and dispose of solid and liquid radioactive wastes. Ten of these projects meet or nearly meet DOE's definition of major: costs exceeding $1 billion in the near term--usually a 5-year window of the project's total estimated life cycle. GAO was asked to determine the (1) extent to which the cost and schedule for DOE's major cleanup projects have changed and key reasons for changes, and (2) factors that may hinder DOE's ability to effectively manage these projects. GAO met with project directors and reviewed project documents for 10 major cleanup projects: 9 above the near-term $1 billion threshold, and 1 estimated to cost between $900 million and $1 billion over the near term."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Health-Care-Associated Infections in Hospitals: Number Associated with Medical Devices Unknown, but Experts Report Provider Practices as a Significant Factor (open access)

Health-Care-Associated Infections in Hospitals: Number Associated with Medical Devices Unknown, but Experts Report Provider Practices as a Significant Factor

Correspondence issued by the Government Accountability Office with an abstract that begins "Health-care-associated infections (HAI) in hospitals can be expensive to treat and, according to the Department of Health and Human Services' (HHS) Centers for Disease Control and Prevention (CDC), HAIs are estimated to be one of the top 10 causes of death in the United States. HAIs can be caused by bacteria or viruses, which may be introduced to a patient through the use of a device used to treat them, such as a needle or tube to deliver medicine, fluids, or blood. Common HAIs that are often associated with the use of medical devices are urinary tract infections (UTI), surgical site infections (SSI), pneumonia, and bloodstream infections (BSI). A number of federal agencies within HHS, including CDC and the Agency for Healthcare Research and Quality (AHRQ), currently collect HAI-related data for a variety of purposes. Nearly half of the states also require public reporting of hospital HAI rates, according to a summary report of these state laws. The Food and Drug Administration Amendments Act of 2007 requires us to conduct work on HAIs in hospitals associated with medical devices. The act defines these infections as those that are …
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Oil and Gas Royalties: MMS's Oversight of Its Royalty-in-Kind Program Can Be Improved through Additional Use of Production Verification Data and Enhanced Reporting of Financial Benefits and Costs (open access)

Oil and Gas Royalties: MMS's Oversight of Its Royalty-in-Kind Program Can Be Improved through Additional Use of Production Verification Data and Enhanced Reporting of Financial Benefits and Costs

Correspondence issued by the Government Accountability Office with an abstract that begins "In fiscal year 2007, the Department of the Interior's (Interior) Minerals Management Service (MMS) collected over $9 billion in oil and natural gas (hereafter referred to as oil and gas) royalties and disbursed these funds to federal, state, and tribal accounts. The federal portion of these royalties, which totaled $6.7 billion, represents one of the country's largest non-tax sources of revenue. In addition to this substantial financial value to the government, oil and gas production on federal lands and waters represents a critical component of the nation's energy portfolio, supplying roughly 35 percent of all the oil and 30 percent of all the gas produced in the United States in 2006. Companies that develop and produce oil and gas resources from federal lands and waters do so under leases obtained from and administered by agencies of Interior--the Bureau of Land Management (BLM) for onshore leases and MMS's Offshore Energy and Minerals Management (OEMM) for offshore leases. Together, these agencies are responsible for overseeing oil and gas operations on more than 28,000 producing leases to help ensure that oil and gas companies comply with applicable laws, regulations, and agency …
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Defense Management: DOD Needs to Establish Clear Goals and Objectives, Guidance, and a Designated Budget to Manage Its Biometrics Activities (open access)

Defense Management: DOD Needs to Establish Clear Goals and Objectives, Guidance, and a Designated Budget to Manage Its Biometrics Activities

A letter report issued by the Government Accountability Office with an abstract that begins "The Department of Defense (DOD), in its response to unconventional threats from terrorists, uses biometrics technologies that identify physical attributes, including fingerprints and iris scans. However, coordinating the development and implementation of biometrics and ensuring interoperability across DOD has been difficult to achieve. Biometrics also is an enabling technology for identity management, a concept that seeks to manage personally identifiable information to enable improved governmentwide sharing and analysis of identity information. GAO was asked to examine the extent to which DOD has established biometrics goals and objectives, implementing guidance for managing biometrics activities, and a designated budget. To address these objectives, GAO reviewed documentation, including DOD biometrics policy and directives, and interviewed key DOD officials involved with making policy and funding decisions regarding biometrics."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
DOD Financial Management: Improvements Are Needed in Antideficiency Act Controls and Investigations (open access)

DOD Financial Management: Improvements Are Needed in Antideficiency Act Controls and Investigations

A letter report issued by the Government Accountability Office with an abstract that begins "Senate Report No. 110-77 directed GAO to review the Department of Defense's (DOD) procedures for Antideficiency Act (ADA) violations. GAO focused on whether (1) existing DOD funds control systems, processes, and internal controls provide reasonable assurance that ADA violations will be prevented or detected and whether key funds control personnel are trained; (2) investigations of ADA violations are processed in accordance with applicable DOD regulations; and (3) DOD tracks and reports metrics pertaining to its ADA investigations and what disciplinary actions are taken when ADA violations have occurred. GAO's review included all 54 ADA military service case files closed in fiscal years 2006 and 2007. GAO did not assess the appropriateness of the conclusions reached or of the disciplinary actions taken for the ADA cases."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Medicare: Trends in Fees, Utilization, and Expenditures for Imaging Services before and after Implementation of the Deficit Reduction Act of 2005 (open access)

Medicare: Trends in Fees, Utilization, and Expenditures for Imaging Services before and after Implementation of the Deficit Reduction Act of 2005

Correspondence issued by the Government Accountability Office with an abstract that begins "Rapid spending growth for Medicare Part B--which covers physician and other outpatient services--has heightened concerns about the long-range fiscal sustainability of Medicare. Medicare Part B expenditures are expected to increase over the next decade at an average annual rate of about 8 percent, which is faster than the projected 4.8 percent annual growth rate in the national economy over this time period. As we noted in our June 2008 report, spending on physician imaging services has been one of the fastest-growing sets of services paid for under the Medicare Part B physician fee schedule (PFS), the payment system used to determine fees for Medicare physician-billed services. From 2000 through 2006, Medicare spending for physician imaging services doubled from about $7 billion to about $14 billion--an average annual increase of 13 percent, compared to an 8 percent increase in spending for all Medicare physician-billed services over the same time period. We also found that by 2006 about two-thirds of spending on physician imaging services occurred in physician office settings--an indicator of a shift toward providing imaging services in physicians' offices as opposed to providing such services in hospital or …
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Defense Acquisitions: Sound Business Case Needed to Implement Missile Defense Agency's Targets Program (open access)

Defense Acquisitions: Sound Business Case Needed to Implement Missile Defense Agency's Targets Program

A letter report issued by the Government Accountability Office with an abstract that begins "The Missile Defense Agency (MDA) is likely to spend $460 million annually on missiles used as targets for flight tests. Executing these tests depends on the quality and availability of targets. Congress asked GAO to assess (1) if MDA is providing reliable targets; (2) the causes of any deficiencies; and (3) if resolutions exist for any problems identified. To do this, GAO analyzed acquisition policies and procedures; flight test data; and budget, program execution, and acquisition materials; and interviewed MDA and DOD officials."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Information Management: The National Archives and Records Administration's Fiscal Year 2008 Expenditure Plan (open access)

Information Management: The National Archives and Records Administration's Fiscal Year 2008 Expenditure Plan

A letter report issued by the Government Accountability Office with an abstract that begins "To preserve and provide access to all types of electronic records, the National Archives and Records Administration (NARA) has been developing an Electronic Records Archive (ERA), including a base system for federal records and a separate system for presidential records, known as the Executive Office of the President (EOP) system. As mandated by the Consolidated Appropriations Act, 2008, NARA must submit an expenditure plan to the Congress that satisfies six conditions. GAO was asked to determine the extent to which NARA's fiscal year 2008 expenditure plan satisfies the conditions and provide any other observations about the plan and the ERA acquisition. To do this, GAO reviewed the expenditure plan, interviewed NARA and contractor officials, and reviewed additional documentation."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Food Safety: Improvements Needed in FDA Oversight of Fresh Produce (open access)

Food Safety: Improvements Needed in FDA Oversight of Fresh Produce

A letter report issued by the Government Accountability Office with an abstract that begins "In recent years, both domestic and imported produce have been linked to reported outbreaks of foodborne illness. Contamination in produce is of particular concern because produce is often consumed raw. The Food and Drug Administration (FDA) has primary responsibility for ensuring the safety of both domestic and imported fresh produce. GAO was asked to examine (1) the resources FDA has spent on fresh produce safety and how it has allocated those resources, (2) the effectiveness of FDA's actions to oversee fresh produce safety, and (3) the extent to which FDA's planned actions to enhance fresh produce oversight address identified challenges. For this review, GAO analyzed FDA spending data and estimates and FDA activities data, reviewed FDA plans, and interviewed FDA officials and others."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Healthy Marriage and Responsible Fatherhood Initiative: Further Progress Is Needed in Developing a Risk-Based Monitoring Approach to Help HHS Improve Program Oversight (open access)

Healthy Marriage and Responsible Fatherhood Initiative: Further Progress Is Needed in Developing a Risk-Based Monitoring Approach to Help HHS Improve Program Oversight

A letter report issued by the Government Accountability Office with an abstract that begins "Strengthening marriages and relationships in low-income families has emerged as a national strategy for enhancing the well-being of children. The Deficit Reduction Act of 2005 (DRA) appropriated $150 million in discretionary grants each year from 2006 through 2010 to implement the Healthy Marriage and Responsible Fatherhood Initiative. To provide insight into how these programs are being implemented and monitored, GAO is reporting on (1) how the Department of Health and Human Services (HHS) awarded grants and the types of organizations that received funding; (2) what activities and services grantees are providing, including those for domestic violence victims; (3) how HHS monitors and assesses program implementation and use of funds; and (4) how program impact is measured. GAO surveyed grantees, interviewed HHS staff, reviewed HHS records and policy, and visited several programs."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Space Acquisitions: Uncertainties in the Evolved Expendable Launch Vehicle Program Pose Management and Oversight Challenges (open access)

Space Acquisitions: Uncertainties in the Evolved Expendable Launch Vehicle Program Pose Management and Oversight Challenges

A letter report issued by the Government Accountability Office with an abstract that begins "The Department of Defense (DOD) plans to spend over $27 billion acquiring launch services through the Evolved Expendable Launch Vehicle (EELV) program over the next 12 years. The EELV program uses two families of commercially owned and operated vehicles to launch satellites. Partly because the commercial space market did not develop as expected, the EELV program has undergone significant changes. These include: adoption of a new acquisition strategy in 2005 that sought to ensure the viability of the two EELV launch vehicle providers, Boeing and Lockheed Martin; the subsequent decision by those two companies to form a joint venture called the United Launch Alliance (ULA); and a 10-year increase in the life of the program. In light of these changes, GAO was asked to (1) determine what uncertainties DOD faces in the EELV program and in the transition to ULA, and (2) assess how DOD is positioned to manage and oversee the effort. To accomplish this, GAO reviewed a wide variety of DOD documents and interviewed DOD and program officials."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
USAID Acquisition and Assistance: Actions Needed to Develop and Implement a Strategic Workforce Plan (open access)

USAID Acquisition and Assistance: Actions Needed to Develop and Implement a Strategic Workforce Plan

A letter report issued by the Government Accountability Office with an abstract that begins "The U.S. Agency for International Development (USAID) over the years has shifted from conducting its own activities to managing acquisition and assistance (A&A) instruments--contracts, grants, and cooperative agreements--awarded to and implemented by mainly nongovernmental entities. For fiscal years 2002 through 2007, USAID's A&A obligations doubled from about $5 billion to $10 billion. A&A staff--contracting officers (CO) and A&A specialists--are primarily responsible for managing A&A instruments. GAO was asked to examine (1) USAID's capacity to develop and implement a strategic A&A workforce plan and (2) the extent to which USAID has implemented a mechanism to evaluate its A&A function. GAO analyzed USAID documents and data, interviewed officials, visited missions in seven countries, and administered a survey to A&A staff."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
EPA's Execution of Its Fiscal year 2007 New Budget Authority for the Enforcement and Compliance Assurance Program in the Regional Offices (open access)

EPA's Execution of Its Fiscal year 2007 New Budget Authority for the Enforcement and Compliance Assurance Program in the Regional Offices

Correspondence issued by the Government Accountability Office with an abstract that begins "This letter responds to a mandate in House Report No. 110-187 that directed GAO to review the Environmental Protection Agency's (EPA) budget execution, specifically to identify the factors that influence EPA's operating plan allocations to the regional offices for a selected national program and to compare and contrast these operating plan allocations with EPA's reported obligations in the regional offices. After discussing this mandate with your offices, we focused our review on EPA's enforcement and compliance assurance program in the regional offices. EPA, in partnership with state agencies, oversees compliance with 44 separate environmental programs. These programs regulate facilities--such as sewage treatment plants, petroleum refineries, and power plants--whose operations could pollute the air, water, and land, and thereby endanger public health and the environment. EPA and its regulatory partners are responsible for ensuring that these regulated facilities comply with program requirements and taking enforcement action in instances of noncompliance. EPA administers its environmental enforcement and compliance assurance responsibilities through its headquarters Office of Enforcement and Compliance Assurance (OECA). While OECA provides overall direction on enforcement policies, and sometimes takes direct enforcement action, EPA's 10 regional offices are responsible …
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Military Operations: DOD Needs to Address Contract Oversight and Quality Assurance Issues for Contracts Used to Support Contingency Operations (open access)

Military Operations: DOD Needs to Address Contract Oversight and Quality Assurance Issues for Contracts Used to Support Contingency Operations

A letter report issued by the Government Accountability Office with an abstract that begins "The Department of Defense (DOD) uses contractors to meet many of its logistical and operational support needs. With the global war on terrorism, there has been a significant increase in deployment of contractor personnel to areas such as Iraq and Afghanistan. In its fiscal year 2007 report, the House Appropriations Committee directed GAO to examine the link between the growth in DOD's operation and maintenance costs and DOD's increased reliance on service contracts. GAO determined (1) the extent to which costs for selected contracts increased and the factors causing the increases, (2) the extent to which DOD provided oversight for selected contracts, and (3) the reasons for DOD's use of contractors to support contingency operations. To address these objectives, GAO reviewed a nonprobability sample of seven DOD contracts for services that provide vital support to contingency operations in Iraq and Afghanistan. GAO reviewed contract requirements, funding documents and DOD guidance for these contracts and interviewed DOD and contractor personnel."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Millennium Challenge Corporation: Summary Fact Sheets for 11 Compacts Entered into Force (open access)

Millennium Challenge Corporation: Summary Fact Sheets for 11 Compacts Entered into Force

Correspondence issued by the Government Accountability Office with an abstract that begins "The Millennium Challenge Corporation (MCC), now in its fourth year of operations, is to provide aid to developing countries that have demonstrated a commitment to ruling justly, encouraging economic freedom, and investing in people. MCC provides assistance to eligible countries through multiyear compact agreements to fund specific programs targeted at reducing poverty and stimulating economic growth. MCC has received appropriations for fiscal years 2004 through 2008 totaling more than $7.5 billion and has set aside about $6.4 billion of this amount for compact assistance. As of August 2008, MCC had signed compacts with 18 countries totaling approximately $6.3 billion; of the 18 signed compacts, 11 compacts had entered into force, obligating a total of approximately $3 billion. The President has requested an additional $2.225 billion for MCC for fiscal year 2009, of which MCC plans to use $1.88 billion for compact assistance to countries currently eligible for compacts. To develop these fact sheets, we compiled and summarized publicly available data from a number of sources, including our previous reporting on MCC. We used information from the World Bank and from Central Intelligence Agency Fact Books to provide a …
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Social Security Disability: Management Controls Needed to Strengthen Demonstration Projects (open access)

Social Security Disability: Management Controls Needed to Strengthen Demonstration Projects

A letter report issued by the Government Accountability Office with an abstract that begins "Since 1980, Congress has required the Social Security Administration (SSA) to conduct demonstration projects to test the effectiveness of possible changes to its Social Security Disability Insurance (DI) and Supplemental Security Income (SSI) programs that could decrease individuals' dependence on benefits or improve program administration. However, in 2004, GAO reported that SSA had not used its demonstration authority effectively. This follow-up report assesses (1) how SSA has used its demonstration authority to test DI and SSI program changes and what information these efforts have yielded and (2) what steps SSA has taken to improve the planning and management of its demonstration projects. To do this, GAO reviewed documents related to SSA's demonstration project management and the steps it took to implement the recommendations in the 2004 report, as well as the projects' designs, evaluations, and costs. GAO also interviewed officials from SSA, its contractors and project sites, and disability experts."
Date: September 26, 2008
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
High-Efficiency Solar Cells for Large-Scale Electricity Generation (open access)

High-Efficiency Solar Cells for Large-Scale Electricity Generation

One strategy for helping the solar industry to grow faster is to use very high efficiency cells under concentrating optics. By using lenses or mirrors to concentrate the light, very small solar cells can be used, reducing the amount of semiconductor material and allowing use of higher efficiency cells, which are now >40% efficient.
Date: September 26, 2008
Creator: Kurtz, S.; Olson, J.; Geisz, J.; Friedman, D.; McMahon, W.; Ptak, A. et al.
Object Type: Article
System: The UNT Digital Library
AMMONIA CONCENTRATION IN SALTSTONE HEADSPACE SUMMARY REPORT (open access)

AMMONIA CONCENTRATION IN SALTSTONE HEADSPACE SUMMARY REPORT

The Saltstone Facility Documented Safety Analysis (DSA) is under revision to accommodate changes in the Composite Lower Flammability Limit (CLFL) from the introduction of Isopar into Tank 50. Saltstone samples were prepared with an 'MCU' type salt solution spiked with ammonia. The ammonia released from the saltstone was captured and analyzed. The ammonia concentration found in the headspace of samples maintained at 95 C and 1 atm was, to 95% confidence, less than or equal to 3.9 mg/L. Tank 50 is fed by several influent streams. The salt solution from Tank 50 is pumped to the salt feed tank (SFT) in the Saltstone Production Facility (SPF). The premix materials cement, slag and fly ash are blended together prior to transfer to the grout mixer. The premix is fed to the grout mixer in the SPF and the salt solution is incorporated into the premix in the grout mixer, yielding saltstone slurry. The saltstone slurry drops into a hopper and then is pumped to the vault. The Saltstone Facility Documented Safety Analysis (DSA) is under revision to accommodate changes in the Composite Lower Flammability Limit (CLFL) from the introduction of Isopar{reg_sign} L into Tank 50. Waste Solidification-Engineering requested that the Savannah …
Date: September 26, 2008
Creator: Zamecnik, J & Alex Cozzi, A
Object Type: Report
System: The UNT Digital Library
Physics Design Requirements for the National Spherical Torus Experiment Liquid Lithium Divertor (open access)

Physics Design Requirements for the National Spherical Torus Experiment Liquid Lithium Divertor

Recent NSTX high power divertor experiments have shown significant and recurring benefits of solid lithium coatings on PFC's to the performance of divertor plasmas in both L- and H- mode confinement regimes heated by high-power neutral beams. The next step in this work is installation of a liquid lithium divertor (LLD) to achieve density control for inductionless current drive capability (e.g., about a 15-25% ne decrease from present highest non-inductionless fraction discharges which often evolve toward the density limit, ne/nGW~1), to enable ne scan capability (x2) in the H-mode, to test the ability to operate at significantly lower density for future ST-CTF reactor designs (e.g., ne/nGW = 0.25), and eventually to investigate high heat-flux power handling (10 MW/m2) with longpulse discharges (>1.5s). The first step (LLD-1) physics design encompasses the desired plasma requirements, the experimental capabilities and conditions, power handling, radial location, pumping capability, operating temperature, lithium filling, MHD forces, and diagnostics for control and characterization.
Date: September 26, 2008
Creator: Kugel, W.; Bell, M.; Berzak,L.; Brooks, A.; Ellis, R.; Gerhardt, S. et al.
Object Type: Article
System: The UNT Digital Library
Countercurrent Flow Limitation Experiments and Modeling for Improved Reactor Safety (open access)

Countercurrent Flow Limitation Experiments and Modeling for Improved Reactor Safety

This project is investigating countercurrent flow and “flooding” phenomena in light water reactor systems to improve reactor safety of current and future reactors. To better understand the occurrence of flooding in the surge line geometry of a PWR, two experimental programs were performed. In the first, a test facility with an acrylic test section provided visual data on flooding for air-water systems in large diameter tubes. This test section also allowed for development of techniques to form an annular liquid film along the inner surface of the “surge line” and other techniques which would be difficult to verify in an opaque test section. Based on experiences in the air-water testing and the improved understanding of flooding phenomena, two series of tests were conducted in a large-diameter, stainless steel test section. Air-water test results and steam-water test results were directly compared to note the effect of condensation. Results indicate that, as for smaller diameter tubes, the flooding phenomena is predominantly driven by the hydrodynamics. Tests with the test sections inclined were attempted but the annular film was easily disrupted. A theoretical model for steam venting from inclined tubes is proposed herein and validated against air-water data. Empirical correlations were proposed for …
Date: September 26, 2008
Creator: Vierow, Karen
Object Type: Report
System: The UNT Digital Library
EUV micro-exposure tool at 0.5 NA for sub-16 nm lithography (open access)

EUV micro-exposure tool at 0.5 NA for sub-16 nm lithography

The resolution limit of present 0.3 NA 13.5 nm wavelength micro-exposure tools is compared to next generation lithography research requirements. Findings suggest that a successor design is needed for patterning starting at the 16 nm semiconductor process technology node. A two-mirror 0.5 NA optical design is presented, and performance expectations are established from detailed optical and lithographic simulation. Here, we report on the results from a SEMATECH program to fabricate a projection optic with an ultimate resolution limit of approximately 11 nm.
Date: September 26, 2008
Creator: Goldstein, Michael; Hudyma, Russ; Naulleau, Patrick & Wurm, Stefan
Object Type: Article
System: The UNT Digital Library
Development of Tc-99m Imaging Agents for Abeta Plaques (open access)

Development of Tc-99m Imaging Agents for Abeta Plaques

Development of SPECT imaging agents based on Tc-99m targeting Aβ plaques is useful for diagnosis of Alzheimer’s disease (AD). A stilbene derivative, [11C]SB-13, showing promise in detecting senile plaques present in AD patients has been reported previously1,2. Based on the 4’-amino-stilbene core structure we have added substituted groups through which a chelating group, N2S2, was conjugated. We report herein a series of Tc-99m labeled stilbene derivative conjugated with a TcO[N2S2] core. The syntheses of stilbenes containing a N2S2 chelating ligand are achieved by a scheme shown. Lipophilic 99mTc stilbene complexes were successfully prepared and purified through HPLC. Preliminary results of in vitro labeling of brain sections from transgenic mice showed very promising plaque labeling. These 99mTc stilbene derivatives are warranted for further evaluations as potential imaging agents targeting amyloid plaques.
Date: September 26, 2008
Creator: Zhi-Ping, Zhuang; Kung, Mei-Ping; Hou, Catherihne & Kung, Hank F.
Object Type: Report
System: The UNT Digital Library
Greensheet (Houston, Tex.), Vol. 39, No. 406, Ed. 1 Friday, September 26, 2008 (open access)

Greensheet (Houston, Tex.), Vol. 39, No. 406, Ed. 1 Friday, September 26, 2008

Free weekly newspaper that includes business and classified advertising.
Date: September 26, 2008
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History