This study examined the statistical consequences of employing various methods of computing and cumulating effect sizes in meta-analysis. Six methods of computing effect size, and three techniques for combining study outcomes, were compared. Effect size metrics were calculated with one-group and pooled standardizing denominators, corrected for bias and for unreliability of measurement, and weighted by sample size and by sample variance. Cumulating techniques employed as units of analysis the effect size, the study, and an average study effect. In order to determine whether outcomes might vary with the size of the meta-analysis, mean effect sizes were also compared for two smaller subsets of studies. An existing meta-analysis of 60 studies examining the effectiveness of computer-based instruction was used as a data base for this investigation. Recomputation of the original study data under the six different effect size formulas showed no significant difference among the metrics. Maintaining the independence of the data by using only one effect size per study, whether a single or averaged effect, produced a higher mean effect size than averaging all effect sizes together, although the difference did not reach statistical significance. The sampling distribution of effect size means approached that of the population of 60 studies …