Article reviews PPARγ as an antitumor agent and summarizes the antineoplastic effects of PPARγ agonists in prostate cancer.

Article on targeting PPARy signaling cascade for the prevention and treatment of prostate cancer.

Article describes study which shows that resistance against fusarium graminearum, the primary casual agent of fusarium head blight (FHB), can be enhanced by flg22, a bacterial microbe-associated molecular pattern (MAMP).

Article reviews the common dysregulation of phosphatidylinositol-3 kinases (PI3K)/Akt/mTOR pathway in gastric cancer (GC) and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment.

Article on targeting the STAT3 signaling pathway in cancer and the role of synthetic and natural inhibitors.

With a current population of just over half a million and a 2030 projected population of approximately one million, expansion throughout Denton County shows no sign of slowing down (NCTCOG). Increasingly, freshwater resources are also facing increased pressure from this urban expansion. Effective assessment and management techniques are necessary to protect the diversity of ecosystem services found within fluvial ecosystems and to mitigate current and future conditions of environmental stressor amplified by urban development. The use of various spatial analysis techniques in environmental assessment present more expedient, cost effective, and broader ranging methods of evaluation than traditional field techniques. One such novel evaluation technique is the Water Quality Corridor Management (WQCM) model, developed by the University of North Texas in cooperation with the Upper Trinity Regional Water District (UTRWD). The WQCM model is a geospatial database that utilizes GIS and remote sensing techniques to assess and prioritize stream reaches according to their overall health and sustainability. This project assessed the viability of the WQCM model in reviewing the status of stream systems, and ultimately, established an accurate mechanism for evaluating the stream corridor and surface water quality draining into Lewisville Lake, a popular recreation site and drinking water source for …

Article expressing two closely related plant FAD3 genes in yeast cells and found that their enzymes produced significantly different amounts of omega-3 fatty acids and that these differences correlated to differences in rates of protein turnover. The findings indicate that Fad3 protein abundance is regulated by a combination of cis-acting degradation signals and the ubiquitin-proteasome pathway and that modulation of Fad3 protein amounts in response to temperature may represent one mechanism of homeoviscous adaptation in plants.

Article accompanying a poster presentation for the 2010 Computational Neuroscience Meeting. This article discusses spike-timing dependent plasticity.

Article discussing temporal decoupling of oxy- and deoxy-hemoglobin hemodynamic responses detected by functional near-infrared spectroscopy (fNIRS)

Article on terpene biosynthesis in glandular trichomes of hop.

This article presents herpetofaunal observations from Limnos and Agios Efstratios, two Asia Minor continental shelf islands in the Aegean Sea. Comprehensive surveys over 88 days in total on Limnos, over a period of nine years, consisted mainly of visual encounter surveys and road cruised observations, revealed the presence of three species of amphibians and twelve species of reptiles, including two new species records for the island (Malpolon insignitus and Pelobates syriacus). The results of these surveys provide a clearer understanding of the extant herpetofauna on Limnos and Agios Efstratios and offer discussion on natural history, possible erroneous historical records and preliminary ecological understanding of the herpetofaunal assemblages residing on these islands.

Two compartment (sediment and water) flow-through model ecosystems were constructed to investigate the compartmentalization of different organic chemicals. Lindane, naphthalene, and mirex were pumped into the systems and resultant compartmental chemical concentrations determined. Steady state concentrations were compared to those predicted by two environmental fate models - EXAMS (Exposure Analysis Modeling System) and SLSA (Simplified Lake and Stream Analysis) which were developed by EPA-Athens, Georgia and HydroQual, Inc., respectively.

Article reporting a chromosome-scale assembly of the T. sinense genome.

This paper discusses the Texas Quail Index, a 5-year citizen science project that evaluated several indices as predictors of bobwhite productivity and abundance during the subsequent fall.

Article accompanying a poster presentation for the 2009 Computational Neuroscience Meeting. This article discusses a theoretical analysis of an alternative CUSUM statistic called CUSUM-slope for detecting signals from background noise in a low signal-to-noise environment.

Article accompanying a poster presentation for the 2008 Computational Neuroscience Meeting. This article discusses the theoretical derivation of EMOTION-I model for emotional feel of sensation.

Article accompanying a poster presentation for the 2008 Computational Neuroscience Meeting. This article discusses the theoretical derivation of EMOTION-II model for happy and unhappy emotions.

Article accompanying a poster presentation for the 2009 Annual Computational Neuroscience Meeting. This article discusses a theoretical model of emotion processing for optimizing the cost function of discrepancy errors between wants and gets.

Article comparing the microbial communities of three isolates from different species of the genus Symbiodinium (formerly known as Symbiodinium clade A) with different ecophysiology, levels of interaction with the animal host, and thermal adaptations. Results suggest that bacteria associated or co-cultured with thermotolerant Symbiodinium might play an important role in thermotolerance.

Article on thymoquinone inhibiting tumor growth and inducing apoptosis in a breast cancer xenograft mouse model and the role of p38 MAPK and ROS.

Article investigates whether thymoquinone (TQ), a bioactive constituent of black seed oil, could suppress the proliferation and induce chemosensitization in human myeloma cells and xenograft mouse model. Overall, the results demonstrate that TQ can enhance the anticancer activity of bortezomib in vitro and in vivo and may have a substantial potential in the treatment of MM.

Data collected on metabolic rates, body temperatures, morphology, plasma T3, and hatching of developing chicken embryos and hatchlings. To understand the role thyroid hormones play in hatch timing and development of thermogenic capacity and metabolic rate plasma thyroid hormone levels were manipulated in chicken embryos beginning at 80% development (day 17 of a 21-day incubation) with either a single dose of triiodo-L-thyronine (T3) or the thyroperoxidase inhibitor methimazole (MMI).

Article describes how induction of high photosynthetic capacity is a key acclimation response to high light for many herbaceous dicot plants. Here, a systems biology approach was utilized to characterize the induction of high photosynthetic capacity in strongly and weakly acclimating Arabidopsis thaliana accessions.

This article reports time-related responses from single-dose intravenous administration of 1 mg/kg Ti₂ NPs to rats, with particular emphasis on titanium quantification in the brain.