Air pollution and endocrine disruptors induce human microbiome imbalances: A systematic review of recent evidence and possible biological mechanisms (open access)

Air pollution and endocrine disruptors induce human microbiome imbalances: A systematic review of recent evidence and possible biological mechanisms

Article presents a systematic review examining the scientific evidence on the effect of environmental toxicants, air pollutants and endocrine disruptors (EDCs), on compositional and diversity of human microbiota.
Date: February 11, 2022
Creator: Mousavi, Sayed Esmaeil; Delgado-Saborit, Juana Maria; Adivi, Anna; Pauwels, Sara & Godderis, Lode
System: The UNT Digital Library
Better together: Protein partnerships for lineage-specific oil accumulation (open access)

Better together: Protein partnerships for lineage-specific oil accumulation

Article reviews recent evidence that protein–protein interactions in each of the three major phases of oil formation appear to have profound effects on specialized oil accumulation. This article is part of the special issue: Physiology and metabolism (2022).
Date: February 24, 2022
Creator: Busta, Lucas; Chapman, Kent Dean & Cahoon, Edgar B.
System: The UNT Digital Library
In vivo Evaluation of Non-viral NICD Plasmid-Loaded PLGA Nanoparticles in Developing Zebrafish to Improve Cardiac Functions (open access)

In vivo Evaluation of Non-viral NICD Plasmid-Loaded PLGA Nanoparticles in Developing Zebrafish to Improve Cardiac Functions

This article presents a study with the purpose to deliver a Notch Intracellular Domain (NICD)-encoded plasmid via poly(lactic-co-glycolic acid) (PLGA) nanoparticles and to investigate the toxic environmental side effects for an in vivo experiment. This research demonstrates that PLGA nanoparticle-mediated target delivery to upregulate Notch related genes can be a potential therapeutic approach with minimum toxic effects.
Date: February 23, 2022
Creator: Messerschmidt, Victoria L.; Chintapula, Uday; Bonetesta, Fabrizio; Laboy-Segarra, Samantha; Naderi, Amir; Nguyen, Kytai T. et al.
System: The UNT Digital Library
Inhaled diesel exhaust particles result in microbiome‑related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice (open access)

Inhaled diesel exhaust particles result in microbiome‑related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice

Article discusses the authors' investigation the hypothesis that exposure to inhaled diesel exhaust particles alters the gut microbiome and promotes microbial-related inflammation and cardiovascular disease biomarkers. To determine whether probiotics could prevent diet or DEP exposure mediated alterations in the gut microbiome or systemic outcomes, a subset of animals on the HF diet were treated orally with 0.3 g/day (~ 7.5 × 108 CFU/day) of Winclove Ecologic® Barrier probiotics throughout the study.
Date: February 9, 2022
Creator: Phillippi, Danielle T.; Daniel, Sarah; Pusadkar, Vaidehi; Youngblood, Victoria L.; Nguyen, Kayla N.; Azad, Rajeev K. et al.
System: The UNT Digital Library
Transcriptome Analysis Uncovers the Gene Expression Profile of Hemileia vastatrix (Race XXXIII) during the Interactions with Resistant and Susceptible Coffee (open access)

Transcriptome Analysis Uncovers the Gene Expression Profile of Hemileia vastatrix (Race XXXIII) during the Interactions with Resistant and Susceptible Coffee

This article presents research to sequence the transcriptome of H. vastatrix race XXXIII to obtain a database for use as a reference in studies of the interaction between the fungus and coffee. In addition, the authors aim to identify differentially expressed genes that have the potential to act as effector proteins during the interaction.
Date: December 27, 2021
Creator: Castro, Isabel Samila Lima; Freitas-Lopes, Rejane do Livramento; de Siqueira Ferreira, Sávio; Maciel, Talles Eduardo Ferreira; Florez, Juan Carlos; Zambolim, Eunize Maciel et al.
System: The UNT Digital Library