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Identification of Novel Antimicrobial Resistance Genes Using Machine Learning, Homology Modeling, and Molecular Docking
Article claims antimicrobial resistance (AMR) threatens the healthcare system worldwide with the rise of emerging drug resistant infectious agents. To infer novel resistance genes, we used complete gene sets of several bacterial strains known to be susceptible or resistant to specific drugs and associated phenotypic information within a machine learning framework that enabled prioritizing genes potentially involved in resistance.
Date:
October 23, 2022
Creator:
Sunuwar, Janak & Azad, Rajeev K.
System:
The UNT Digital Library
Sustainable nutrition: a spatially explicit modeling approach for urban land use planning
Article describes how rapid urbanization has influenced the transformation of local and global food systems, altering the availability, access to, and distribution of healthy food. Micronutrient deficiency and hunger have been exacerbated worldwide. The author's research proposes a simulation strategy to evaluate the impact of agricultural land use and crop choices on nutritional production in rapidly growing urban areas.
Date:
October 14, 2022
Creator:
Torres, Angélica Torres; Tiwari, Chetan & Atkinson, Samuel F.
System:
The UNT Digital Library
Recurrent urinary tract infection and estrogen shape the taxonomic ecology and function of the postmenopausal urogenital microbiome
Article describes how postmenopausal women are severely affected by recurrent urinary tract infection (rUTI). The authors perform shotgun metagenomics and advanced culture on urine from a controlled cohort of postmenopausal women to identify urogenital microbiome compositional and function changes linked to rUTI susceptibility.
Date:
October 18, 2022
Creator:
Neugent, Michael D.; Kumar, Ashwani; Hulyalkar, Neha V.; Lutz, Kevin C.; Nguyen, Vivian H.; Fuentes, Jorge L. et al.
System:
The UNT Digital Library