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Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation (open access)

Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation

Article proposing a model in which phosphorylation of sites 1 and 2 occurs sequentially. The model proposes that trypsin treatment of the inactive holoenzyme removes an inhibitory rac-binding domain which blocks MgATP access to the catalytic site. The pseudosubstrate domain at site 1 is autophosphorylated and subsequent bimolecular autophosphorylation at site 2 fully opens the catalytic site.
Date: September 8, 1995
Creator: Benner, Gretchen E.; Dennis, Patrick B. & Masaracchia, Ruthann A.
Object Type: Article
System: The UNT Digital Library
N-acylethanolamide metabolizing enzymes are upregulated in human neural progenitor-derived neurons exposed to sub-lethal oxidative stress (open access)

N-acylethanolamide metabolizing enzymes are upregulated in human neural progenitor-derived neurons exposed to sub-lethal oxidative stress

Article is a study determining whether ReN cells, a superior cell model system for studying neurodevelopment, differentiation, and neuroprotection, express proteins involved in canonical eCB NAE signaling and whether oxidative stress can induce their expression. This study is a first step toward determining how oxidative stress affects CB1, CB2, FAAH, NAAA, and NAPE-PLD expression and their potential defense against oxidative stress.
Date: August 8, 2022
Creator: Duncan, Scott R.; Riordan, Sean M.; Hall, Conner W.; Payne, Andrew J.; Chapman, Kent Dean & Koulen, Peter
Object Type: Article
System: The UNT Digital Library
Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis (open access)

Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis

This article reports the first physiological 2Fe-2S cluster acceptor for both NEET proteins as human Anamorsin (also known as cytokine induced apoptosis inhibitor-1; CIAPIN-1).
Date: October 8, 2015
Creator: Lipper, Colin H.; Paddock, Mark L.; Onuchic, José N.; Mittler, Ron; Nechushtai, Rachel & Jennings, Patricia A.
Object Type: Article
System: The UNT Digital Library
Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene (open access)

Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene

Article presents a case study of a 35 year-old Caucasian woman who experienced multiple vertebral fractures two months after her second pregnancy. The results suggest a potential role of heterozygous WNT1 variants in the pathogenesis of early-onset osteoporosis. The authors suggest that teriparatide is one of the most appropriate available therapies for such cases.
Date: August 8, 2022
Creator: Campopiano, Maria Cristina; Fogli, Antonella; Michelucci, Angela; Mazoni, Laura; Longo, Antonella; Borsari, Simona et al.
Object Type: Article
System: The UNT Digital Library
Corrigendum: The Differences Between Malate Dehydrogenase Malic Enzymes and Nicotinamide Adenine Dinucleotide Phosphate Malic Enzymes Subtypes of C₄ Photosynthesis: More Than Decarboxylating Enzymes (open access)

Corrigendum: The Differences Between Malate Dehydrogenase Malic Enzymes and Nicotinamide Adenine Dinucleotide Phosphate Malic Enzymes Subtypes of C₄ Photosynthesis: More Than Decarboxylating Enzymes

This is a correction of a previously released article. A mistake was found in Figure 2 of the published work. The names of the cell types, “mesophyll cell” and “bundle sheath” were erroneously interchanged.
Date: March 8, 2019
Creator: Rao, Xiaolan & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Decoding of movement direction using optical imaging of motor cortex (open access)

Decoding of movement direction using optical imaging of motor cortex

Article accompanying a poster presentation for the 2013 Computational Neuroscience Annual Meeting. This article discusses the decoding of movement direction using optical imaging of motor cortex.
Date: July 8, 2013
Creator: Tam, Nicoladie D. & Zouridakis, George
Object Type: Article
System: The UNT Digital Library
Embryonic developmental oxygen preconditions cardiovascular functional response to acute hypoxic exposure and maximal β-adrenergic stimulation of anesthetized juvenile American alligators (Alligator mississippiensis) (open access)

Embryonic developmental oxygen preconditions cardiovascular functional response to acute hypoxic exposure and maximal β-adrenergic stimulation of anesthetized juvenile American alligators (Alligator mississippiensis)

Article investigating the effect of embryonic hypoxia on the cardiovascular phenotype of 4-year-old American alligators (Alligator mississippiensis). The findings indicate that embryonic hypoxia in crocodilians alters the cardiovascular phenotype, changing the juvenile response to acute hypoxia and β-adrenergic stimulation.
Date: January 26, 2018
Creator: Smith, Brandt R.; Crossley, Janna; Elsey, Ruth M.; Hicks, James W. & Crossley, Dane A., II
Object Type: Article
System: The UNT Digital Library
Evaluation of Threshold Selection Methods for Adaptive Kernel Density Estimation in Disease Mapping (open access)

Evaluation of Threshold Selection Methods for Adaptive Kernel Density Estimation in Disease Mapping

This article assesses the relative performance of threshold selection methods in terms of resolution and reliability for disease mapping.
Date: May 8, 2018
Creator: Ruckthongsook, Warangkana; Tiwari, Chetan; Oppong, Joseph R. & Natesan, Prathiba
Object Type: Article
System: The UNT Digital Library
Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet (open access)

Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Article investigating if the exposure to diesel exhaust particles (DEP) can alter commensal lung microbiota, thereby promoting alterations in the lung’s immune and inflammatory responses. This article also explores if diet contributes to the alteration of the commensal lung microbiome.
Date: January 8, 2021
Creator: Daniel, Sarah; Phillippi, Danielle; Schneider, Leah J.; Nguyen, Kayla N.; Mirpuri, Julie & Lund, Amie K.
Object Type: Article
System: The UNT Digital Library
Exposure to diesel exhaust particulates and desert sand dust generates microvesicle particles and platelet-activating factor agonists (open access)

Exposure to diesel exhaust particulates and desert sand dust generates microvesicle particles and platelet-activating factor agonists

The authors address the editor in their article, stating that the majority of the general population, particularly, servicemen and women deployed across the globe are exposed to various airborne hazards, including diesel exhaust particulate (DEP) and desert sand dust (DSD). Studies, including the author's study, have shown that exposure to ROS-generating pro-oxidative stressors ranging from environmental carcinogens to pollutants, including cigarette smoke, produces a class of potent phospholipid mediators, Platelet-activating factor (PAF) and PAF-like agonists via oxidative cleavage of lipid membrane glycerophosphocholines (GPCs).
Date: April 8, 2023
Creator: Thyagarajan, Anita; Rapp, Christine M.; Schneider, Leah; Lund, Amie K.; Travers, Jeffrey B. & Sahu, Ravi P.
Object Type: Article
System: The UNT Digital Library
Finding New Cell Wall Regulatory Genes in Populus trichocarpa Using Multiple Lines of Evidence (open access)

Finding New Cell Wall Regulatory Genes in Populus trichocarpa Using Multiple Lines of Evidence

Article describes study which searched for genes with putatively unknown roles in regulating cell wall biosynthesis using an extended network-based Lines of Evidence (LOE) pipeline to combine multiple omics data sets in P. trichocarpa, including gene coexpression, gene comethylation, population level pairwise SNP correlations, and two distinct SNP-metabolite Genome Wide Association Study (GWAS) layers.
Date: October 8, 2019
Creator: Furches, Anna; Kainer, David; Weighill, Deborah; Large, Annabel; Jones, Piet; Walker, Angelica M. et al.
Object Type: Article
System: The UNT Digital Library
Functional Analysis of Metabolic Channeling and Regulation in Lignin Biosynthesis: A Computational Approach (open access)

Functional Analysis of Metabolic Channeling and Regulation in Lignin Biosynthesis: A Computational Approach

Article on the functional analysis of metabolic channeling and regulation in lignin biosynthesis.
Date: November 8, 2012
Creator: Lee, Yun; Escamilla-Treviño, Luis; Dixon, R. A. & Voit, Eberhard O.
Object Type: Article
System: The UNT Digital Library
In silico guided structural and functional analysis of genes with potential involvement in resistance to coffee leaf rust: A functional marker based approach (open access)

In silico guided structural and functional analysis of genes with potential involvement in resistance to coffee leaf rust: A functional marker based approach

Article presents novel insights into the molecular nature of the SH genes, thereby opening new avenues for coffee rust resistance molecular breeding.
Date: July 8, 2020
Creator: Ferreira, Svio Siqueira; Barka, Geleta Dugassa; Caixeta, Eveline Teixeira & Zambolim, Larcio
Object Type: Article
System: The UNT Digital Library
Interplay between Bladder Microbiota and Urinary Antimicrobial Peptides: Mechanisms for Human Urinary Tract Infection Risk and Symptom Severity (open access)

Interplay between Bladder Microbiota and Urinary Antimicrobial Peptides: Mechanisms for Human Urinary Tract Infection Risk and Symptom Severity

This article explores the interrelationship between the urinary microbiota and host antimicrobial peptides as mechanisms for urinary tract infection risk.
Date: December 8, 2014
Creator: Nienhouse, Vanessa; Gao, Xiang; Dong, Qunfeng; Nelson, David E.; Toh, Evelyn; McKinley, Kathleen et al.
Object Type: Article
System: The UNT Digital Library
Jasmonic Acid Is Required for Plant Acclimation to a Combination of High Light and Heat Stress (open access)

Jasmonic Acid Is Required for Plant Acclimation to a Combination of High Light and Heat Stress

Article studying the responses of Arabidopsis (Arabidopsis thaliana) plants to a combination of high light and heat stress (HL+HS) conditions. The study reveals that Jasmonic acid (JA) plays an important role in the acclimation of plants to a combination of HL+HS.
Date: October 8, 2019
Creator: Sengupta, Soham; Azad, Rajeev K.; Balfagón, Damián; Gómez-Cadenas, Aurelio; Fritschi, Felix B.; Mittler, Ron et al.
Object Type: Article
System: The UNT Digital Library
Loss of Rare Fish Species from Tropical Floodplain Food Webs Affects Community Structure and Ecosystem Multifunctionality in a Mesocosm Experiment (open access)

Loss of Rare Fish Species from Tropical Floodplain Food Webs Affects Community Structure and Ecosystem Multifunctionality in a Mesocosm Experiment

Article on the loss of rare fish species from tropical floodplain food webs and how this affects community structure and ecosystem multifunctionality in a mesocosm experiment.
Date: February 3, 2012
Creator: Pendleton, Richard M.; Hoeinghaus, David; Gomes, Luiz C. & Agostinho, Angela A.
Object Type: Article
System: The UNT Digital Library
Plant Fatty Acid Amide Hydrolases (open access)

Plant Fatty Acid Amide Hydrolases

Patent relating to plant fatty acid amide hydrolases (FAAH) coding sequences.
Date: January 8, 2008
Creator: Chapman, Kent D.; Shrestha, Rhidaya; Blancaflor, Elison B. & Dixon, R. A.
Object Type: Patent
System: The UNT Digital Library
POSMM: an efficient alignment-free metagenomic profiler that complements alignment-based profiling (open access)

POSMM: an efficient alignment-free metagenomic profiler that complements alignment-based profiling

Article presents POSMM, Python-Optimized Standard Markov Model classifier, which is a new incarnation of the Markov model approach to metagenomic sequence analysis. The authors claim that by combining POSMM with ultrafast classifiers such as Kraken2, their complementary strengths can be leveraged to produce higher overall accuracy in metagenomic sequence classification than by either as a standalone classifier. POSMM is a user-friendly and highly adaptable tool designed for broad use by the metagenome scientific community.
Date: March 8, 2023
Creator: Burks, David J.; Pusadkar, Vaidehi & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Silicon versus Superbug: Assessing Machine Learning's Role in the Fight against Antimicrobial Resistance (open access)

Silicon versus Superbug: Assessing Machine Learning's Role in the Fight against Antimicrobial Resistance

Article describes how, in his 1945 Nobel Prize acceptance speech, Sir Alexander Fleming warned of antimicrobial resistance (AMR) if the necessary precautions were not taken diligently. This paper explores the applications of ML in predicting and understanding AMR, highlighting its potential in revolutionizing healthcare practices.
Date: November 8, 2023
Creator: Coxe, Tallon & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library
Trypsin induces an aversive response in zebrafish by PAR2 activation in keratinocytes (open access)

Trypsin induces an aversive response in zebrafish by PAR2 activation in keratinocytes

Article using zebrafish as a model and identifies that trypsin induces an aversive response in zebrafish larvae and adult zebrafish. Results show that the trypsin activates PAR2 on keratinocytes signaling the brain, and this pathway of trypsin-induced escape response will provide a unique communication mechanism in zebrafish.
Date: October 8, 2021
Creator: Alsrhani, Abdullah; Raman, Revathi & Jagadeeswaran, Pudur
Object Type: Article
System: The UNT Digital Library
Ultrastructure of Azotobacter vinelandii (open access)

Ultrastructure of Azotobacter vinelandii

Article discussing research on vegetative cells and cysts for Azotobacter vinelandii 12837 prepared for electron microscopy by several methods assumed to preserve structural details destroyed by techniques previously reported in literature.
Date: August 8, 1970
Creator: Vela, G. Roland, 1927-; Cagle, Gerald D. & Holmgren, P. R.
Object Type: Article
System: The UNT Digital Library
Validation of an emotional model by EEG recordings of neural responses (open access)

Validation of an emotional model by EEG recordings of neural responses

Article on the validation of an emotional model by EEG recordings of neural responses.
Date: July 8, 2013
Creator: Tam, Nicoladie D.
Object Type: Article
System: The UNT Digital Library