Article describes how taxonomic profiling of ancient metagenomic samples is challenging due to the accumulation of specific damage patterns on DNA over time. The authors performed a comprehensive evaluation on simulated metagenomes representing human dental calculus microbiome, with the level of DNA damage successively raised to mimic modern to ancient metagenomes.

Article describes how kudzu produces both O- and C-glycosylated isoflavones, with puerarin (C-glucosyl daidzein) as an important bioactive compound. The authors go on to explain how expression of recombinant UGTs in Escherichia coli and candidate C-glycosyltransferases in Medicago truncatula were used to explore substrate specificities, and gene silencing of UGT and key isoflavone biosynthetic genes in kudzu hairy roots employed to test hypotheses concerning the substrate(s) for C-glycosylation.

Article reporting a chromosome-scale assembly of the T. sinense genome.

Article investigating the potential effects of isorhamnetin (IH), a 3′-O-methylated metabolite of quercetin on the peroxisome proliferator-activated receptor γ (PPAR-γ) signaling cascade using proteomics technology platform, GC cell lines, and xenograft mice model. The study y proposes a novel agent for gastric cancer treatment.

This article shows that that the coordinated read-write activity of the epigenetic machinery extends to the cytoskeleton, with PBRM1 in the PBAF chromatin remodeling complex reading microtubule methyl marks written by the SETD2 histone methyltransferase. This article opens a previously unknown window into how chromatin remodeler defects can drive disease via both epigenetic and cytoskeletal dysfunction.

This article applies a developmental 3-dimensional critical window experimental design for a vertebrate, using time, temperature, and phenotypic response (i.e., variables measured). To assess thermal effects on fish development, the authors examined trout hatchling phenotypes following rearing in constant temperatures (5, 10, 15 and 17.5 °C) and following exposure to increased temperature above 5 °C during specific developmental windows.

Article using a combination of biochemical and genetic approaches to show how ABA can regulate lignin biosynthesis. This work provides a basis for designing trees and other biomass plants that are better adapted to stress and climate change. This article includes a correction on the first page.

Article on the composition of the four cell wall fractions in diverse maize genotypes and to understand how this composition influences the resistance to pests, ethanol capacity and digestibility. Results evidence that there is no maize cell wall ideotype among the tested for optimal performance for various uses, and maize plants should be specifically bred for each particular application.

This article uses high-throughput screening to identify two phytochemicals that are effective in promoting resilience against stress by moduling brain synaptic plasticity and peripheral inflammation.

This article investigates the patterns of shared polymorphism and selection at non-MHC immune genes in five grouse species from Centrocercus and Tympanuchus genera.

This article reports the synthesis and related biological activity of novel dihydropyrimidones.

This article discusses the test of the function of FIT2 in plant cells by ectopically expressing mouse (Mus musculus) FIT2 in Nicotiana tabacum suspension-cultured cells, Nicotiana benthamiana leaves and Arabidopsis thaliana plants.

Article on increased disease susceptibility of transgenic tobacco plants with suppressed levels of preformed phenylpropanoid products.

Article on genomics-based selection and functional characterization of triterpene glycosyltransferases from the model legume Medicago truncatula.

Article on proanthocyanidins -- a final frontier in flavonoid research?

Article on phenylalanine ammonia-lyase (PAL) from tobacco (Nicotiana tabacum) and characterization of the four tobacco PAL genes and active heterotetrameric enzymes.

Article on thymoquinone inhibiting tumor growth and inducing apoptosis in a breast cancer xenograft mouse model and the role of p38 MAPK and ROS.

Article on PPAR-γ, a nuclear transcription factor that plays a critical role in the development of gastric cancer.

Article on targeting the STAT3 signaling pathway in cancer and the role of synthetic and natural inhibitors.

This article discusses a web-based multi-genome synteny viewer for customized data.

Presentation for the 2009 University Scholars Day at the University of North Texas discussing research on the potential transcriptional activation of the Foxn1 gene by the Runx1 factor.

Presentation for the 2009 University Scholars Day at the University of North Texas discussing research on reactive oxygen species role in the closure of the Ductus Arteriosus (DA).

The research in this paper examines the incidence of tuberculosis (TB) among foreign-born Asians living in Tarrant County, Texas.

Presentation for the 2009 University Scholars Day at the University of North Texas discussing research on searching for the genes that encode nodulation symbiosis between medicago truncatula and rhizobia.