Article reviews the common dysregulation of phosphatidylinositol-3 kinases (PI3K)/Akt/mTOR pathway in gastric cancer (GC) and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment.
This article reports the draft F. vesca genome, which was sequenced to x39 coverage using second-generation technology, assembled de novo and then anchored to the genetic linkage map into seven pseudochromosomes.
December 26, 2010
Shulaev, Vladimir; Sargent, Daniel J.; Crowhurst, Ross N.; Mockler, Todd C.; Folkerts, Otto; Delcher, Arthur et al.
This article contains RNA sequencing analysis of Arabidopsis thaliana plants subjected to light stress in order to identify and characterize rapid changes in the steady-state level of different transcripts in response to light stress.
This article investigates the effect of breed-specific yolk composition on embryonic broiler and layer chicken phenotypes, using an ex ovo, xenobiotic technique that allows the transfer of broiler and layer chicken embryos from their natural yolks to novel yolk environments.
January 26, 2011
Ho, Dao H.; Reed, Wendy L. & Burggren, Warren W.
This article discusses the ecological and and evolutionary significance of such epigenetic inheritance in a comparative physiological context, and provides a number of caveats and warnings regarding the interpretation of transgenerational phenotype modification as a true epigenetic phenomenon.
This article presents radio and X-ray observations, as well as optical light curves, for a subset of 26 BL Lac candidates from the Sloan Digital Sky Survey lacking strong radio emission and with z < 2.2.
July 26, 2010
Plotkin, Richard M.; Anderson, Scott F.; Brandt, William Nielsen; Diamond-Stanic, Aleksandar M.; Fan, Xiaohui; MacLeod, Chelsea L. et al.
Article on the constitutive activation of proinflammatory transcription factors such as STAT3 and NF-KB that play a pivotal role in the proliferation and survival of squamous cell carcinoma of the head and neck (HNSCC).
June 26, 2013
Li, Feng; Shanmugam, Muthu K.; Chen, Luxi; Chatterjee, Snehajyoti; Basha, Jeelan; Kumar, Alan Prem et al.