Targeting hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase for lignin modification in Brachypodium distachyon (open access)

Targeting hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase for lignin modification in Brachypodium distachyon

This article conducts a study to evaluate the utility of Hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT) as a target for lignin modification in a species with an “incomplete” shikimate shunt. Results imply that this gene is a preferred target for biotechnological improvement of grasses for bioprocessing.
Date: February 27, 2021
Creator: Serrani-Yarce, Juan Carlos; Escamilla-Treviño, Luis; Barros, Jaime; Gallego-Giraldo, Lina; Pu, Yunqiao; Ragauskas, Arthur J. (Arthur Jonas), 1957- et al.
System: The UNT Digital Library
Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target (open access)

Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

Article identifying novel epigenetic regulators for tfpia and exploiting this information to discover a drug that enhances tfpia mRNA levels and prolongation of TTO. This discovery provides the basis for testing whether UNC6852 could be used as an antithrombotic drug.
Date: July 27, 2021
Creator: Raman, Revathi; Fallatah, Weam; Al Qaryoute, Ayah; Dhinoja, Sanchi & Jagadeeswaran, Pudur
System: The UNT Digital Library
Exploring the socio-economic and environmental components of infectious diseases using multivariate geovisualization: West Nile Virus (open access)

Exploring the socio-economic and environmental components of infectious diseases using multivariate geovisualization: West Nile Virus

Article focusing on West Nile Virus (WNV), a mosquito borne pathogen, as a case study for spatial data visualization of environmental characteristics of a vector’s habitat alongside human demographic composition for understanding potential public health risks of infectious disease.
Date: March 2, 2020
Creator: Kala, Abhishek K.; Atkinson, Samuel F. & Tiwari, Chetan
System: The UNT Digital Library