Resource Type

Language

NREL Combined Experimental Final Report--Phase II (open access)

NREL Combined Experimental Final Report--Phase II

Predicting peak power and loads on a fixed-pitch wind turbine. How does the performance of the airfoil in the wind tunnel differ from the performance of an operating horizontal-axis wind turbine (HAWT)?
Date: August 1, 1992
Creator: Butterfield, C. P.; Musial, W. P.; Scott, G. N. & Simms, D. A.
System: The UNT Digital Library
Geophysics: Building E5375 decommissioning, Aberdeen Proving Ground (open access)

Geophysics: Building E5375 decommissioning, Aberdeen Proving Ground

Building E5375 was one of ten potentially contaminated sites in the Canal Creek area of the Edgewood section of Aberdeen Proving Ground examined by a geophysical team from Argonne National Laboratory in April and May 1992. Noninvasive geophysical surveys, including magnetics, electrical resistivity, and ground-penetrating radar (GPR), were conducted around the perimeter of the building to guide a sampling program prior to decommissioning and dismantling. Several anomalies wear, noted: (1) An underground storage tank located 25 ft east of Building E5375 was identified with magnetic, resistivity, and GPR profiling. (2) A three-point resistivity anomaly, 12 ft east of the northeast comer of Building E5374 (which borders Building E5375) and 5 ft south of the area surveyed with the magnetometer, may be caused by another underground storage tank. (3) A 2,500-gamma magnetic anomaly near the northeast corner of the site has no equivalent resistivity anomaly, although disruption in GPR reflectors was observed. (4) A one-point magnetic anomaly was located at the northeast comer, but its source cannot be resolved. A chaotic reflective zone to the east represents the radar signature of Building E5375 construction fill.
Date: August 1, 1992
Creator: McGinnis, M.G.; McGinnis, L.D.; Miller, S.F. & Thompson, M.D.
System: The UNT Digital Library
The influence of Savannah River discharge and changing SRS cooling water requirements on the potential entrainment of ichthyoplankton at the SRS Savannah River intakes (open access)

The influence of Savannah River discharge and changing SRS cooling water requirements on the potential entrainment of ichthyoplankton at the SRS Savannah River intakes

Entrainment (i.e., withdrawal of fish larvae and eggs in cooling water) at the SRS Savannah River intakes is greatest when periods of high river water usage coincide with low river dischargeduring the spawning season. American shad and striped bass are the two species of greatest concern because of their recreational and/or commercial importance and because they produce drifting eggs and larvae vulnerable to entrainment. In the mid-reaches of the Savannah River, American shad and striped bass spawn primarily during April and May. An analysis of Savannah River discharge during April and May 1973--1989 indicated the potential for entrainment of 4--18% of the American shad and striped bass larvae and eggs that drifted past the SRS. This analysis assumed the concurrent operation of L-, K-, and P-Reactors. Additional scenarios investigated were: (1) shutting down L- and P-Reactors, and operating K-Reactor with a recycle cooling tower; and (2) shutting down L- and P-Reactors, eliminating minimum flows to Steel Creek, and operating K-Reactor with a recycle cooling tower. The former scenario reduced potential entrainment to 0.7--3.3%, and the latter scenario reduced potential entrainment to 0.20.8%. Thus, the currently favored scenario of operating K-Reactor with a cooling tower and not operating L- and P-Reactors …
Date: August 1, 1992
Creator: Paller, M.H.
System: The UNT Digital Library
Summary of ORNL long-term surveillance at the FFTF (open access)

Summary of ORNL long-term surveillance at the FFTF

Oak Ridge National Laboratory has used an automated system between 1983 and 1987 to collect and analyze primary system noise data at the Fast Flux Test Facility (FFTF) located in Hanford, Washington, System operation and data handling are described, data collection efforts are summarized, and principal findings are presented.
Date: August 1, 1992
Creator: Damiano, B. & Thie, J.A.
System: The UNT Digital Library
Pennsylvania Source Term Tracking System (open access)

Pennsylvania Source Term Tracking System

The Pennsylvania Source Term Tracking System tabulates surveys received from radioactive waste generators in the Commonwealth of radioactive waste is collected each quarter from generators using the Low-Level Radioactive Waste Management Quarterly Report Form (hereafter called the survey) and then entered into the tracking system data base. This personal computer-based tracking system can generate 12 types of tracking reports. The first four sections of this reference manual supply complete instructions for installing and setting up the tracking system on a PC. Section 5 presents instructions for entering quarterly survey data, and Section 6 discusses generating reports. The appendix includes samples of each report.
Date: August 1, 1992
Creator: unknown
System: The UNT Digital Library
Experiments on the nuclear interactions of pions and electrons. [Dept. of Physics, Univ. of Virginia] (open access)

Experiments on the nuclear interactions of pions and electrons. [Dept. of Physics, Univ. of Virginia]

The analysis of the deuterium content in the CD target used in an experiment to study the [pi] + d [yields] 2p reaction at incident pion energies from 4 to 20 MeV was completed. The final paper describing this experiment will be submitted for publication this summer. Analysis of LAMPF Exp. on pion absorption in [sup 4]He is continuing. In 1991, we collaborated with D. Pocanic from the Univ. of Virginia on a measurement at LAMPF of the [pi][sup 0] production in [pi] + p interactions. This run proved the validity of the method and additional data were obtained in a second run during the summer of 1992, using a new target. Current collaborations at LAMPF include the search for the decay [mu][sup +] [yields] e[sup +] + [gamma](MEGA) and a measurement of the Michel [rho] parameter in the decay [mu] [yields] e + v + v. A U.Va.--PSI collaboration is measuring pion beta decay to an accuracy of less than 1%, using a large acceptance CsI detector to measure the [pi][sup 0] following decay of stopped [pi][sup +] mesons. Most of the U.Va. effort is devoted to the CEBAF Large Acceptance Spectrometer (CLAS) program to the construction of the …
Date: August 1, 1992
Creator: Minehart, R.C. & Ziock, K.O.H.
System: The UNT Digital Library
Materials Development Program, Ceramic Technology Project addendum to program plan: Cost effective ceramics for heat engines (open access)

Materials Development Program, Ceramic Technology Project addendum to program plan: Cost effective ceramics for heat engines

This is a new thrust in the Ceramic Technology project. This effort represents an expansion of the program and an extension through FY 1997. Moderate temperature applications in conventional automobile and truck engines will be included along with high-temp. gas turbine and low heat rejection diesel engines. The reliability goals are expected to be met on schedule by end of FY 1993. Ceramic turbine rotors have been run (in DOE's ATTAP program) for 1000 h at 1370C and full speed. However, the cost of ceramic components is a deterrrent to near-term commercialization. A systematic approach to reducing this cost includes the following elements: economic cost modeling, ceramic machining, powder synthesis, alternative forming and densification processes, yield improvement, system design studies, standards development, and testing and data base development. A draft funding plan is outlined. 6 figs, 1 tab.
Date: August 1, 1992
Creator: unknown
System: The UNT Digital Library
Healy clean coal project (open access)

Healy clean coal project

The objective of the Healy Clean Coal Project is to demonstrate the integration of an advanced combustor and a heat recovery system with both high and low temperature emission control processes. Resulting emission levels of SO[sub 2], NO[sub x], and particulates are expected to be significantly better than the federal New source Performance standards. During this past quarter, engineering and design continued on the boiler, combustion flue gas desulfurization (FGD), and turbine/generator systems. Balance of plant equipment procurement specifications continue to be prepared. Construction activities commenced as the access road construction got under way. Temporary ash pond construction and drilling of the supply well will be completed during the next quarter.
Date: August 1, 1992
Creator: unknown
System: The UNT Digital Library
First annual report on the Biological Monitoring and Abatement Program at Oak Ridge National Laboratory (open access)

First annual report on the Biological Monitoring and Abatement Program at Oak Ridge National Laboratory

As a condition of the National Pollutant Discharge Elimination System (NPDES) permit issued to Oak Ridge National Laboratory (ORNL) on April 1, 1986, a Biological Monitoring and Abatement Program (BMAP) was developed for White Oak Creek (WOC); selected tributaries of WOC, including Fifth Creek, First Creek, Melton Branch, and Northwest Tributary; and the Clinch River. BMAP consists of seven major tasks that address both radiological and nonradiological contaminants in the aquatic and terrestrial environs on-site and the aquatic environs off-site. These tasks are (1) toxicity monitoring; (2) bioaccumulation monitoring of nonradiological contaminants in aquatic biota; (3) biological indicator studies; (4) instream ecological monitoring; (5) assessment of contaminants in the terrestrial environment; (6) radioecology of WOC and White Oak Lake (WOL); and (7) contaminant transport, distribution, and fate in the WOC embayment-Clinch River-Watts Bar Reservoir system. This document, the first of a series of annual reports presenting the results of BMAP, describes studies that were conducted from March through December 1986.
Date: August 1, 1992
Creator: Loar, J.M. (ed.); Adams, S. M.; Blaylock, B. G.; Boston, H. L.; Frank, M. L.; Garten, C. T. et al.
System: The UNT Digital Library
Fugitive dust control experiments using soil fixatives on vehicle traffic surfaces (open access)

Fugitive dust control experiments using soil fixatives on vehicle traffic surfaces

This report presents the results of engineering scale dust control experiments using soil fixative for contamination control during handling of transuranic waste. These experiments focused on controlling dust during retrieval operations of buried waste where waste and soil are intimately mixed. Sources of dust generation during retrieval operations include digging, dumping, and vehicle traffic. Because contaminants are expected to attach to soil particles and move with the generated dust, control of the dust spread may be the key to contamination control. Dust control techniques examined in these experiments include the use of soil fixatives to control generation of fugitive dusts during vehicle traffic operations. Previous experiments conducted in FY 1990 included testing of the soil fixative, ENTAC. These experiments showed that ENTAC was effective in controlling dust generation but had several undesirable properties such as slow cure times and clogged the pumps and application nozzles. Therefore, other products would have to be evaluated to find a suitable candidate. As a result, two soil fixatives were tested in these present experiments, COHEREX-PM, an asphalt emulsion product manufactured by Witco Corporation and FLAMBINDER, a calcium lignosulfonate product manufactured by Flambeau Corporation. The results of the experiments include product performance and recommended application …
Date: August 1, 1992
Creator: Winberg, M. R. & Wixom, V. E.
System: The UNT Digital Library
Chemical Hygiene and Safety Plan (open access)

Chemical Hygiene and Safety Plan

The objective of this Chemical Hygiene and Safety Plan (CHSP) is to provide specific guidance to all LBL employees and contractors who use hazardous chemicals. This Plan, when implemented, fulfills the requirements of both the Federal OSHA Laboratory Standard (29 CFR 1910.1450) for laboratory workers, and the Federal OSHA Hazard Communication Standard (29 CFR 1910.1200) for non-laboratory operations (e.g., shops). It sets forth safety procedures and describes how LBL employees are informed about the potential chemical hazards in their work areas so they can avoid harmful exposures and safeguard their health. Generally, communication of this Plan will occur through training and the Plan will serve as a the framework and reference guide for that training.
Date: August 1, 1992
Creator: Berkner, K.
System: The UNT Digital Library
Preliminary design studies on the Broad Application Test Reactor (open access)

Preliminary design studies on the Broad Application Test Reactor

This report describes progress made at the Idaho National Engineering Laboratory during the first three quarters of Fiscal Year (FY) 1992 on the Laboratory-Directed Research and Development (LDRD) project to perform preliminary design studies on the Broad Application Test Reactor (BATR). This work builds on the FY-92 BATR studies, which identified anticipated mission and safety requirements for BATR and assessed a variety of reactor concepts for their potential capability to meet those requirements. The main accomplishment of the FY-92 BATR program is the development of baseline reactor configurations for the two conventional conceptual test reactors recommended in the FY-91 report. Much of the present report consists of descriptions and neutronics and thermohydraulics analyses of these baseline configurations. In addition, we considered reactor safety issues, compared the consequences of steam explosions for alternative conventional fuel types, explored a Molten Chloride Fast Reactor concept as an alternate BATR design, and examined strategies for the reduction of operating costs. Work planned for the last quarter of FY-92 is discussed, and recommendations for future work are also presented.
Date: August 1, 1992
Creator: Terry, W. J. (ed.); Terry, W. K.; Ryskamp, J. M.; Jahshan, S. N.; Fletcher, C. D.; Moore, R. L. et al.
System: The UNT Digital Library
Environmental Restoration Quality Program Plan (open access)

Environmental Restoration Quality Program Plan

The Martin Marietta Energy Systems, Inc., Environmental Restoration (ER) Program was initially chartered on October 1, 1989, as a entral Environmental Restoration Division'' to manage the investigation and remediation of inactive sites and facilities that have been declared surplus and have no further programmatic use. The Energy Systems ER Division was established to support the DOE Oak Ridge Field Office (DOE-OR) consolidated ER Program. The DOE-OR Assistant Manager for Environmental Restoration and Waste Management provides program and budget direction to the Energy Systems ER Program for environmental restoration activities at the sites operated by Energy Systems (Oak Ridge K-25 Site, Oak Ridge National Laboratory, Oak Ridge Y-12 Plant, Paducah Gaseous Diffusion Plant, Portsmouth Gaseous Diffusion Plant) and at the off-site locations. The Energy Systems ER Division is specifically charged with assessing these sites for potential contamination and managing the cleanup processes. The Energy Systems Environmental Restoration Division was chartered on October 1, 1989, as a central organization to manage the Remedial Action (RA) Program. The purpose of this document is to ensure that: senior ER management provides planning, organization, direction, control, and support to achieve the organization's objectives; the line organization achieves quality; and overall performance is reviewed and evaluated …
Date: August 1, 1992
Creator: Colley, J. S.
System: The UNT Digital Library
A Calcium Oxide Sorbent Process for Bulk Separation of Carbon Dioxide (open access)

A Calcium Oxide Sorbent Process for Bulk Separation of Carbon Dioxide

This research project is investigating the technical feasibility of a high-temperature, high-pressure (HTHP) process for the bulk separation of CO[sub 2] from coal-derived gas. Phase I research, which utilized an electrobalance reactor, was completed during the previous quarter and final experimental results have been reported. Phase II research involves a switch from the electrobalance reactor to a laboratory-scale fixed-bed reactor having feed and product gas analysis capability. Initial effort during Phase II has been limited to project planning including the design and construction of the fixed-bed reactor, developing specifications for gas analysis, and ordering the gas chromatograph system. These activities are described in the present report.
Date: August 1, 1992
Creator: Harrison, D. P.
System: The UNT Digital Library
The development of an integrated multistage fluid bed retorting process. [Kentort II process] (open access)

The development of an integrated multistage fluid bed retorting process. [Kentort II process]

This report summarizes the progress made on the development of an integrated multistage fluidized bed retorting process (KENTORT II) during the period of April 1, 1992 through June 30, 1992. The KENTORT II process includes integral fluidized bed zones for pyrolysis, gasification, and combustion of the oil shale. The purpose of this program is to design and test the KENTORT II process at the 50-lb/hr scale. The raw oil shale sample for the program was mined, prepared, characterized and stored this quarter. The shale that was chosen was from the high-grade zone of the Devonian Cleveland Member of the Ohio Shale in Montgomery County, Kentucky. The shale was mined and then transported to the contractor's crushing facility where it was crushed, double-screened, and loaded into 85 55-gal barrels. The barrels, containing a total of 25-30 tons of shale, were transported to the (CAER) Center for Applied Energy Research where the shale was double-screened, analyzed and stored. A major objective of the program is the study of solid-induced secondary coking and cracking reactions. A valved fluidized bed reactor has been the primary apparatus used for this study prior to this quarter, but two additional techniques have been initiated this quarter for …
Date: August 1, 1992
Creator: Carter, S. D.; Taulbee, D. N.; Robl, T. L. & Hower, J. C.
System: The UNT Digital Library
The Weak Decay of Helium Hypernuclei (open access)

The Weak Decay of Helium Hypernuclei

A [Lambda] hyperon replaces a neutron in a nucleus to form a hypernucleus via the [sup A]X(K[sup [minus]], [pi][sup [minus]]) [sub [Lambda]][sup A]X reaction at 750 MeV/c (Brookhaven Experiment 788). The free [Lambda] decay rates [Gamma]([Lambda] [yields] p[pi][sup [minus]]) and [Gamma]([Lambda] [yields] n[pi][sup 0]) are diminished due to Pauli blocking; but a non-mesonic decay mode, nucleon stimulated decay N[Lambda] [yields] Nn, is present and is detected via the energetic decay nucleon(s) ([approx] 400MeV/c). Measurements of the various hypernuclear decay rates [Gamma]([Lambda] [yields] p[pi][sup [minus]]), [Gamma]([Lambda] [yields] n[pi][sup 0]) and [Gamma]([Lambda]n [yields] nn) provides insight into the strong modification of the weak interaction such as the baryon-baryon [Delta]I =[1/2] rule. The hypernuclear state is isolated by momentum analysis of (K[sup [minus]], [pi][sup [minus]]) target reaction. Out-of-beam large volume scintillation detectors and tracking chambers axe used to make particle identification of the hypernuclear decay products by time-of-flight, dE/dx, and range. The kinetic energy of the decay neutrons are measured by time of flight using the large volume 100 element neutron detector system. The hypernuclear lifetime is directly measured using precision scintillator counters and tracking chambers. Measurements of the various decay rates as well as the total lifetime are discussed for [sub [Lambda]][sup …
Date: August 1, 1992
Creator: Athanas, M. J.
System: The UNT Digital Library
Alpha low-level stored waste systems design study (open access)

Alpha low-level stored waste systems design study

The Stored Waste System Design Study (SWSDS), commissioned by the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examines relative life-cycle costs associated with three system concepts for processing the alpha low-level waste (alpha-LLW) stored at the Radioactive Waste Management Complex's Transuranic Storage Area at the INEL. The three system concepts are incineration/melting; thermal treatment/solidification; and sort, treat, and repackage. The SWSDS identifies system functional and operational requirements and assesses implementability; effectiveness; cost; and demonstration, testing, and evaluation (DT E) requirements for each of the three concepts.
Date: August 1, 1992
Creator: Feizollahi, F.; Teheranian, B. (Morrison Knudson Corp., San Francisco, CA (United States). Environmental Services Div.) & Quapp, W.J. (EG and G Idaho, Inc., Idaho Falls, ID (United States))
System: The UNT Digital Library
Fast Excitation Wiggler Field Measurement Results (open access)

Fast Excitation Wiggler Field Measurement Results

As part of the program of Inverse Free Electron Laser (IFEL) Accelerator Development, the development of fast excitation, planar wigglers with high K magnitude has been pursued. This paper discusses the observed characteristics of a variable period length, tapered, wiggler as well as the procedures of measurement. The behaviour of a constant period length magnet with varying Vanadium Permendur (VaP) and field reflector thickness is also discussed.
Date: August 1, 1992
Creator: Armendariz, J.; Gallardo, J.; Romano, T. & van Steenbergen, A.
System: The UNT Digital Library
Locations of criticality alarms and nuclear accident dosimeters at Hanford (open access)

Locations of criticality alarms and nuclear accident dosimeters at Hanford

Hanford facilities that contain fissionable materials capable of achieving critical mass are monitored with nuclear accident dosimeters (NADS) in compliance with the requirements of DOE Order 5480.11, Chapter XI, Section 4.c. (DOE 1988). The US Department of Energy (DOE) Richland Field Office (RL) has assigned the responsibility for maintaining and evaluating the Hanford NAD system to the Instrumentation and External Dosimetry (I ED) Section of Pacific Northwest Laboratory's (PNL's) Health Physics Department. This manual provides a description of the Hanford NAD, criteria and instructions for proper NAD placement, and the locations of these dosimeters onsite.
Date: August 1, 1992
Creator: unknown
System: The UNT Digital Library
Carbon emissions and sequestration in forests: Case studies from seven developing countries (open access)

Carbon emissions and sequestration in forests: Case studies from seven developing countries

Forests are a major source of carbon dioxide emissions in developing countries, in most cases far exceeding the emissions from the energy sector. To date, however, efforts at quantifying forestry emissions have produced a wide range of results. In order to assist policymakers in developing measures to reduce emissions' levels and to increase carbon sequestration, the Tropical Forest Research Network (F-7) has undertaken this effort to improve the precision of emissions estimates and to identify possible response options in the forestry sector. This paper summarizes the results of one component of this work. The Tropical Forest Research Network (F-7) was established in 1990 as part of the Intergovernmental Panel on Climate Change's (IPCC) activities in examining growing emissions of greenhouse gases and their potential impact on the global climate. Unlike past methods, this study relied on a network of participants from developing countries to prepare estimates of carbon emissions. The participating countries -- Brazil, China, India, Indonesia, Malaysia, Mexico and Thailand -- currently represent an estimated two-thirds of the annual deforestation of closed moist forests. This study gives an estimate of 837 million tonnes of carbon emissions from deforestation and logging in the F-7 countries in 1990. A proportional projection …
Date: August 1, 1992
Creator: Makundi, W.; Sathaye, J. (eds.) & Cerutti, O. M.
System: The UNT Digital Library
Chemistry of radiation damage to wire chambers (open access)

Chemistry of radiation damage to wire chambers

Proportional counters are used to study aspects of radiation damage to wire chambers (wire aging). Principles of low-pressure, rf plasma chemistry are used to predict the plasma chemistry in electron avalanches (1 atm, dc). (1) Aging is studied in CF{sub 4}/iC{sub 4}H{sub 10} gas mixtures. Wire deposits are analyzed by Auger electron spectroscopy. An apparent cathode aging process resulting in loss of gain rather than in a self-sustained current is observed in CF{sub 4}-rich gases. A four-part model considering plasma polymerization of the hydrocarbon, etching of wire deposits by CF{sub 4}, acceleration of deposition processes in strongly etching environments, and reactivity of the wire surface is developed to understand anode wire aging in CF{sub 4}/iC{sub 4}H{sub 10} gases. Practical guidelines suggested by the model are discussed. (2) Data are presented to suggest that trace amounts of Freons do not affect aging rates in either dimethyl ether or Ar/C{sub 2}H{sub 6}. Apparent loss of gain is explained by attachment of primary electrons to a continuously increasing concentration of Freon 11 (CCl{sub 3}F) in the counter gas. An increase in the concentration of Freon 11 in dimethyl ether is caused by a distillation process in the gas supply bottle and is a …
Date: August 1, 1992
Creator: Wise, J.
System: The UNT Digital Library
Computer assisted multiplex sequencing (open access)

Computer assisted multiplex sequencing

The objectives of this project are automation and optimization of multiplex sequencing. This year we have integrated direct transfer electrophoresis, automated multiplex hybridizations and automated film reading and applied this toward sequencing of three contiguous E. coli cosmids. Primers for the directed dideoxy sequence walking and sequence confirmation steps were synthesized with a 15 base tag complimentary to an alkaline phosphatase conjugate. A higher throughput synthesis device is well along in testing as are new automated hybridization devices. We have developed software for automatically annotating ORFs and databases of precise termini of proteis and RNA.
Date: August 1, 1992
Creator: Church, G.M.
System: The UNT Digital Library
Impact evaluation of an energy dollar sign avings plan project at Elf Atochem North America (open access)

Impact evaluation of an energy dollar sign avings plan project at Elf Atochem North America

This impact evaluation of an energy conservation measure (ECM) that was recently installed at Elf Atochem North America (Atochem) was conducted for the Bonneville Power Administration (Bonneville) as part of an evaluation of its Energy savings Plan (E$P) Program. The Program makes acquisition payments to firms that install energy conservation measures in their industrial processes. The objective of this impact evaluation was to assess how much electrical energy is being saved at Atochem as a result of the E$P and to determine how much the savings cost Bonneville and the region. The impact of the ECM was evaluated with a combination of engineering analysis, financial analysis, site visit and interview, review of previous program submittals and review of process evaluation results from 1989. The ECM itself consists of adding anode area to each of the sodium chlorate (chlorate) cells at Atochem's Tacoma facility. Increasing the anode area reduces the current density, which reduces cell resistance at the same current, thus reducing energy consumption at the same chlorate production rate. Energy savings resulting from this ECM are expected to average about 24,000,000 kWh/yr or about 1000 kWh/ton of chlorate produced. The net cost of the ECM was $1,410,400, and Atochem received …
Date: August 1, 1992
Creator: Brown, D. R. & Spanner, G. E.
System: The UNT Digital Library
Chromosome region-specific libraries for human genome analysis (open access)

Chromosome region-specific libraries for human genome analysis

During the grant period progress has been made in the successful demonstration of regional mapping of microclones derived from microdissection libraries; successful demonstration of the feasibility of converting microclones with short inserts into yeast artificial chromosome clones with very large inserts for high resolution physical mapping of the dissected region; Successful demonstration of the usefulness of region-specific microclones to isolate region-specific cDNA clones as candidate genes to facilitate search for the crucial genes underlying genetic diseases assigned to the dissected region; and the successful construction of four region-specific microdissection libraries for human chromosome 2, including 2q35-q37, 2q33-q35, 2p23-p25 and 2p2l-p23. The 2q35-q37 library has been characterized in detail. The characterization of the other three libraries is in progress. These region-specific microdissection libraries and the unique sequence microclones derived from the libraries will be valuable resources for investigators engaged in high resolution physical mapping and isolation of disease-related genes residing in these chromosomal regions.
Date: August 1, 1992
Creator: Kao, Fa-Ten.
System: The UNT Digital Library