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Altitudinal gradients in Magellanic sub-Antarctic lagoons: the effect of elevation on freshwater macroinvertebrate diversity and distribution (open access)

Altitudinal gradients in Magellanic sub-Antarctic lagoons: the effect of elevation on freshwater macroinvertebrate diversity and distribution

In this article, freshwater macroinvertebrate diversity associated with lakes and ponds along the altitudinal gradient of a Magellanic sub-Antarctic watershed are assessed. A monotonic decline in species richness was observed with increasing elevation, with simpler and more even community composition at higher altitude. This pattern differs from the mid-peak trend found in streams of the same watershed. Functional feeding group structure also diminished with increasing elevation.
Date: July 29, 2019
Creator: Rendoll Cárcamo, Javier; Contador, Tamara; Gañán, Melisa; Pérez Troncoso, Carolina; Maldonado Márquez, Alan; Convey, Peter et al.
Object Type: Article
System: The UNT Digital Library
Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine? (open access)

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

Article reviews the common dysregulation of phosphatidylinositol-3 kinases (PI3K)/Akt/mTOR pathway in gastric cancer (GC) and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment.
Date: October 26, 2015
Creator: Singh, Shikha Satendra; Yap, Wei Ney; Arfuso, Frank; Kar, Shreya; Wang, Chao; Cai, Wanpei et al.
Object Type: Article
System: The UNT Digital Library
Coprologic survey of endoparasites from Darwin’s fox (Pseudalopex fulvipes) in Chiloé, Chile (open access)

Coprologic survey of endoparasites from Darwin’s fox (Pseudalopex fulvipes) in Chiloé, Chile

Article on parasite presence in the critically endangered Darwin's fox (Pseudalopex fulvipes) in Chile. Parasites found include species and genera reported for the first time in Darwin's fox.
Date: January 1, 2012
Creator: Jiménez, Jaime E.; Briceño, C.; Alcaíno, H.; Vásquez, P.; Funk, S. & González-Acuña, D.
Object Type: Article
System: The UNT Digital Library
Body shape differences in a pair of closely related Malawi cichlids and their hybrids: Effects of genetic variation, phenotypic plasticity, and transgressive segregation (open access)

Body shape differences in a pair of closely related Malawi cichlids and their hybrids: Effects of genetic variation, phenotypic plasticity, and transgressive segregation

Article describes study which investigated the contributions of both genetic and plastic components for differences in body shape in two species of Lake Malawi cichlids using wild‐caught specimens and a common garden experiment.
Date: May 10, 2017
Creator: Husemann, Martin; Tobler, Michael; McCauley, Cagney; Ding, Baoqing & Danley, Patrick D.
Object Type: Article
System: The UNT Digital Library
Overexpression of fatty acid amide hydrolase induces early flowering in Arabidopsis thaliana (open access)

Overexpression of fatty acid amide hydrolase induces early flowering in Arabidopsis thaliana

Article investigates the nature of the early flowering phenotype of AtFAAH overexpression.
Date: February 20, 2012
Creator: Teaster, Neal D.; Keereetaweep, Jantana; Kilaru, Aruna; Wang, Yuh-Shuh; Tang, Yuhong; Tran, Christopher N.-Q. et al.
Object Type: Article
System: The UNT Digital Library
Florigen and anti-florigen – a systemic mechanism for coordinating growth and termination in flowering plants (open access)

Florigen and anti-florigen – a systemic mechanism for coordinating growth and termination in flowering plants

Article describes study establishing FLOWERING LOCUS T (FT) as a key flower-promoting gene in photoperiodic systems.
Date: September 16, 2014
Creator: Lifschitz, Eliezer; Ayre, Brian G. & Eshed, Yuval
Object Type: Article
System: The UNT Digital Library
The Differences between NAD-dependent malic enzyme and NADP-dependent malic enzyme Subtypes of C4 Photosynthesis: More than Decarboxylating Enzymes (open access)

The Differences between NAD-dependent malic enzyme and NADP-dependent malic enzyme Subtypes of C4 Photosynthesis: More than Decarboxylating Enzymes

Article addresses the differences in evolutionary scenario, leaf anatomy, and especially C4 metabolic flow, C4 transporters, and cell-specific function deduced from recently reported cell-specific transcriptomic, proteomic, and metabolic analyses of NAD-dependent malic enzyme (NAD-ME) and NADP-dependent malic enzyme (NADP-ME) subtypes.
Date: October 13, 2016
Creator: Rao, Xiaolan & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Metabolomics as a hypothesis-generating functional genomics tool for the annotation of Arabidopsis thaliana genes of “unknown function” (open access)

Metabolomics as a hypothesis-generating functional genomics tool for the annotation of Arabidopsis thaliana genes of “unknown function”

Article describes the analysis of Arabidopsis metabolomics data sets acquired by a consortium that includes five analytical laboratories, bioinformaticists, and biostatisticians, which aims to develop and validate metabolomics as a hypothesis-generating functional genomics tool.
Date: February 10, 2012
Creator: Quanbeck, Stephanie M.; Brachova, Libuse; Campbell, Alexis A.; Guan, Xin; Perera, Ann; He, Kun et al.
Object Type: Article
System: The UNT Digital Library
Lipid signaling in plants (open access)

Lipid signaling in plants

Article on the publication of a volume of articles of researchers addressing various fundamental questions in lipid signaling in plants.
Date: June 27, 2013
Creator: Wang, Xuemin & Chapman, Kent Dean
Object Type: Article
System: The UNT Digital Library
Biochemical and molecular-genetic characterization of SFD1’s involvement in lipid metabolism and defense signaling (open access)

Biochemical and molecular-genetic characterization of SFD1’s involvement in lipid metabolism and defense signaling

Article describes study which sought to to determine if the dihydroxyacetone phosphate (DHAP) reductase activity and chloroplast localization are required for the Arabidopsis thaliana SFD1 (suppressor of fatty acid desaturase deficiency1) gene’s involvement in galactolipid metabolism and systemic acquired resistance (SAR) signaling.
Date: February 7, 2012
Creator: Lorenc-Kukula, Katarzyna; Chaturvedi, Ratnesh; Roth, Mary; Welti, Ruth & Shah, Jyoti
Object Type: Article
System: The UNT Digital Library
Cardiac and metabolic physiology of early larval zebrafish (Danio rerio) reflects parental swimming stamina (open access)

Cardiac and metabolic physiology of early larval zebrafish (Danio rerio) reflects parental swimming stamina

Article describes experiment in which mature adult zebrafish (Danio rerio) were subjected to a swimming performance test that allowed separation into low swimming stamina or high swimming stamina groups in order to determine if inherited traits that support enhanced swimming stamina in offspring appear only in juveniles and/or adults, or if these traits actually appear earlier in the morphologically quite different larvae.
Date: February 24, 2012
Creator: Gore, Matthew & Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
Erratum for Vilo et al., Draft Genome Sequence of Cupriavidus sp. Strain SK-3, a 4-Chlorobiphenyl- and 4-Chlorobenzoic Acid-Degrading Bacterium (open access)

Erratum for Vilo et al., Draft Genome Sequence of Cupriavidus sp. Strain SK-3, a 4-Chlorobiphenyl- and 4-Chlorobenzoic Acid-Degrading Bacterium

Erratum for the article "Draft Genome Sequence of Cupriavidus sp. Strain SK-3, a 4-Chlorobiphenyl- and 4-Chlorobenzoic Acid-Degrading Bacterium".
Date: July 31, 2014
Creator: Vilo, Claudia A.; Benedik, Michael J.; Ilori, Matthew Olusoji & Dong, Qunfeng
Object Type: Article
System: The UNT Digital Library
Primer registro de Vespula vulgaris (Linnaeus 1758) (Hymenoptera: Vespidae) en la isla Navarino, Chile (open access)

Primer registro de Vespula vulgaris (Linnaeus 1758) (Hymenoptera: Vespidae) en la isla Navarino, Chile

This article documents the presence of the common wasp Vespula vulgaris (Linnaeus 1758) on Navarino Island, Cape Horn Biosphere Reserve, Southern Chile. The common wasp V. vulgaris is an introduced species in the Southern Hemisphere that has been reported in Australia, New Zealand, Tasmania, Argentina and South-central Chile.
Date: 2016
Creator: Rendoll Cárcamo, Javier; Contador, Tamara; Crego, Ramiro D.; Jordán, Natalia I.; Schüttler, Elke; Gañán, Melisa et al.
Object Type: Article
System: The UNT Digital Library
Muconic acid production from methane using rationally-engineered methanotrophic biocatalysts (open access)

Muconic acid production from methane using rationally-engineered methanotrophic biocatalysts

Article demonstrates bioconversion of methane to muconic acid, a dicarboxylic acid that can be upgraded to an array of platform chemicals, by three gammaproteobacterial methanotrophs.
Date: November 25, 2019
Creator: Henard, Calvin A.; Akberdin, Ilya R.; Kalyuzhnaya, Marina G. & Guarnieri, Michael T.
Object Type: Article
System: The UNT Digital Library
Elevated CO2 increases energetic cost and ion movement in the marine fish intestine (open access)

Elevated CO2 increases energetic cost and ion movement in the marine fish intestine

Article describes study which aimed to gain resolution in assessing the energetic demand associated with acid-base regulation by examining ion movement and O2 consumption rates of isolated intestinal tissue from Gulf toadfish acclimated to control or 1900 μatm CO2 (projected for year 2300).
Date: September 29, 2016
Creator: Heuer, Rachael M. & Grosell, Martin
Object Type: Article
System: The UNT Digital Library
Gold at what cost? Another megaproject threatens biodiversity in the Amazon (open access)

Gold at what cost? Another megaproject threatens biodiversity in the Amazon

Article discusses concerns and controversy related to the gold mining ‘Volta Grande Project’ at the Xingu River in northern Brazil.
Date: June 26, 2017
Creator: Tófoli, Raffael M.; Dias, Rosa M.; Alves, Gustavo H. Zaia; Hoeinghaus, David J.; Gomes, Luiz C.; Baumgartner, Matheus T. et al.
Object Type: Article
System: The UNT Digital Library
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer (open access)

SPHK1 regulates proliferation and survival responses in triple-negative breast cancer

Article describes study suggesting that the inhibation of sphingosine kinase 1 (SPHK1) can attenuate ERK1/2 and AKT signaling and reduce growth of triple-negative breast cancer (TNBC) cells in vitro and in a xenograft SCID mouse model.
Date: March 27, 2014
Creator: Datta, Arpita; Loo, Ser Yue; Huang, Baohua; Wong, Lingkai; Tan, Sheryl S.L.; Tan, Tuan Zea et al.
Object Type: Article
System: The UNT Digital Library
Molecular Dynamics Simulations of the [2Fe–2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release (open access)

Molecular Dynamics Simulations of the [2Fe–2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release

Article examines NEET proteins and aberrant cluster release, which is implicated in a variety of human diseases, including cancer.
Date: October 31, 2017
Creator: Pesce, Luca; Calandrini, Vania; Marjault, Henri-Baptiste; Lipper, Colin H.; Rossetti, Gulia; Mittler, Ron et al.
Object Type: Article
System: The UNT Digital Library
Hypoxic level and duration differentially affect embryonic organ system development of the chicken (Gallus gallus) (open access)

Hypoxic level and duration differentially affect embryonic organ system development of the chicken (Gallus gallus)

This article investigates how key organ systems are affected by hypoxia. The results indicated that either modest hypoxia (15% O2) throughout development, or hypoxia at any level during the late stages (d 11 to 18), increased the heart and chorioallantoic membrane weight, which partly compensated for the detrimental effects of hypoxia on embryonic development.
Date: December 11, 2019
Creator: Zhang, H. & Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
Effect of selection for commercially productive traits on the plasticity of cardiovascular regulation in chicken breeds during embryonic development (open access)

Effect of selection for commercially productive traits on the plasticity of cardiovascular regulation in chicken breeds during embryonic development

Article investigates basic cardiovascular physiology in the Red Junglefowl, the broiler, and the White Leghorn breeds at 90% of incubation. The authors aimed to identify breed-specific features of arterial blood pressure and heart rate as well as the physiological mechanisms regulating them. They concluded that selection for rapid growth shifts cardiovascular regulatory plasticity to emphasize mechanisms that modulate pressure, and that selection for egg-laying capacity emphasizes mechanisms that modulate heart rate.
Date: October 1, 2012
Creator: Crossley, Dane A., II & Altimiras, J.
Object Type: Article
System: The UNT Digital Library
Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model (open access)

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model

Article investigates whether thymoquinone (TQ), a bioactive constituent of black seed oil, could suppress the proliferation and induce chemosensitization in human myeloma cells and xenograft mouse model. Overall, the results demonstrate that TQ can enhance the anticancer activity of bortezomib in vitro and in vivo and may have a substantial potential in the treatment of MM.
Date: December 18, 2013
Creator: Siveen, Kodappully Sivaraman; Mustafa, Nurulhuda; Li, Feng; Kannaiyan, Radhamani; Ahn, Kwang Seok; Kumar, Alan Prem et al.
Object Type: Article
System: The UNT Digital Library
γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mammalian target of rapamycin pathway in an orthotopic mouse model (open access)

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mammalian target of rapamycin pathway in an orthotopic mouse model

Article describing an investigation into whether γ-tocotrienol can abrogate angiogenesis-mediated tumor growth in hepatocellular carcinoma (HCC) and if so, through what molecular mechanisms.
Date: March 31, 2014
Creator: Siveen, Kodappully Sivaraman; Ahn, Kwang Seok; Ong, Tina H.; Shanmugam, Muthu K.; Li, Feng; Yap, Wei Ney et al.
Object Type: Article
System: The UNT Digital Library
Correction: Role of novel histone modifications in cancer (open access)

Correction: Role of novel histone modifications in cancer

Correction to the article "Role of novel histone modifications in cancer".
Date: April 10, 2018
Creator: Shanmugam, Muthu K.; Arfuso, Frank; Arumugam, Surendar; Chinnathambi, Arunachalam; Jinsong, Bian; Warrier, Sudha R. et al.
Object Type: Article
System: The UNT Digital Library
Development and use of a switchgrass (Panicum virgatum L.) transformation pipeline by the BioEnergy Science Center to evaluate plants for reduced cell wall recalcitrance (open access)

Development and use of a switchgrass (Panicum virgatum L.) transformation pipeline by the BioEnergy Science Center to evaluate plants for reduced cell wall recalcitrance

Article examines the creation of a transformation pipeline (TP) to produce plants with decreased recalcitrance and a laboratory information management system (LIMS) for data compilation from these plants. While many genes accepted into the TP resulted in transgenic switchgrass without modified lignin or biomass content, a group of genes with potential to improve lignocellulosic biofuel yields was identified. Results from transgenic lines targeting xyloglucan and lignin structure provide examples of the types of information available on switchgrass lines produced within BioEnergy Science Center (BESC).
Date: December 22, 2017
Creator: Nelson, Richard S.; Stewart, C. Neal; Gou, Jiqing; Holladay, Susan; Gallego-Giraldo, Lina; Flanagan, Amy et al.
Object Type: Article
System: The UNT Digital Library