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Targeting Peroxisome Proliferator-Activated Receptor-Gamma (PPARγ) Signaling Cascade for the Prevention and Treatment of Prostate Cancer (open access)

Targeting Peroxisome Proliferator-Activated Receptor-Gamma (PPARγ) Signaling Cascade for the Prevention and Treatment of Prostate Cancer

Article reviews PPARγ as an antitumor agent and summarizes the antineoplastic effects of PPARγ agonists in prostate cancer.
Date: November 14, 2012
Creator: Sikka, Sakshi; Chen, Luxi; Sethi, Gautam & Kumar, Alan Prem
System: The UNT Digital Library
Effect of N-Methyl-pyrrolidone (NMP) on the Equilibrium Solubility of Meloxicam in Aqueous Media: Correlation, Dissolution Thermodynamics, and Preferential Solvation (open access)

Effect of N-Methyl-pyrrolidone (NMP) on the Equilibrium Solubility of Meloxicam in Aqueous Media: Correlation, Dissolution Thermodynamics, and Preferential Solvation

Article describes a study of the drug Meloxicam in N-methyl-pyrrolidone (NMP)–aqueous mixtures at several temperatures to expand the solubility database about pharmaceutical compounds in aqueous–mixed solvents. Meloxicam is preferentially hydrated in water-rich mixtures but preferentially solvated by NMP in the composition interval of 0.16 < x1 < 1.00.
Date: October 14, 2022
Creator: Tinjacá, Darío; Martínez, Fleming; Almanza, Ovidio A.; Jouyban, Abolghasem & Acree, William E. (William Eugene)
System: The UNT Digital Library