This article is a case study discussing a case of a 40-year-old female with isolated splenic sarcoidosis found to have isolated splenomegaly with multiple hypodense splenic lesions and no other multisystem involvement. Isolated splenomegaly is very rare and an uncommon presentation of sarcoidosis. This case is clinically challenging because of the extensive differential diagnosis. The authors conclude that sarcoidosis of the spleen, although rare, should be considered in the differential diagnosis of the patients presenting with systemic symptoms and splenomegaly.

This review summarizes the characteristics, evidences and development of CSCs, as well as implications and challenges for cancer treatment. Surgery, radiotherapy and chemotherapy are universally recognized as the most effective anti-cancer therapies. Recent studies have showed that cancer stem cells (CSCs), a small subpopulation of tumor cells, can generate bulk populations of nontumorigenic cancer cell progeny through the self-renewal and differentiation processes.

Study examines intermittent hypoxic conditioning's (IHC) ability to alleviate harmful PTSD effects on a rat's heart, liver, and brain.

Study investigated the role of the neuroprotective kynurenic acid (KYNA) in RGC death against retinal ischemia/reperfusion (I/R) injury.

This article's study endeavors to determine if p53 is responsible for cisplatin sensitization by NSC109268. Results have implications for sensitivity of ovarian cancer cells to cisplatin independent of p53.