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Bioabsorbable zinc ion induced biphasic cellular responses in vascular smooth muscle cells (open access)

Bioabsorbable zinc ion induced biphasic cellular responses in vascular smooth muscle cells

This article explores the short-term effects of extracellular Zn²⁺ on human smooth muscle cells.
Date: January 6, 2016
Creator: Ma, Jun; Zhao, Nan & Zhu, Donghui
System: The UNT Digital Library
An approach for reliably identifying high-frequency oscillations and reducing false-positive detections (open access)

An approach for reliably identifying high-frequency oscillations and reducing false-positive detections

Article states that high-frequency oscillation (HFO), classified as ripples (80-240 Hz) and fast ripples (240-500 Hz), is regarded as a promising biomarker of epilepsy. The authors presented an integrated, multi-layered procedure capable of automatically rejecting HFOs from a variety of common false positives, such as motion, background signals, and sharp transients.
Date: September 2, 2022
Creator: Zhou, Yufeng; You, Jing; Kumar, Udaya; Weiss, Shennan A.; Bragin, Anatol; Engel Jr., Jerome et al.
System: The UNT Digital Library
Decellularization Strategies for Regenerative Medicine: From Processing Techniques to Applications (open access)

Decellularization Strategies for Regenerative Medicine: From Processing Techniques to Applications

This review compares the advantages and disadvantages of decellularization methods in terms of their ability to retain desired extracellular matrix characteristics for particular tissues and organs.
Date: April 30, 2017
Creator: Gilpin, Anna & Yang, Yong
System: The UNT Digital Library
In-vitro biomineralization and biocompatibility of friction stir additively manufactured AZ31B magnesium alloy-hydroxyapatite composites (open access)

In-vitro biomineralization and biocompatibility of friction stir additively manufactured AZ31B magnesium alloy-hydroxyapatite composites

Article presents research where friction stir additive manufacturing technique was employed to fabricate AZ31B magnesium-hydroxyapatite composite. The study aims to evaluate effect of hydroxyapatite (HA, Ca₁₀(PO₄)₆OH₂), a ceramic similar to natural bone, into AZ31B Mg alloy matrix on biomineralization and biocompatibility.
Date: June 30, 2020
Creator: Ho, Yee-Hsien; Man, Kun; Joshi, Sameehan; Pantawane, Mangesh V.; Wu, Tso-Chang; Yang, Yong et al.
System: The UNT Digital Library
Biofunctionalization of metallic implants by calcium phosphate coatings (open access)

Biofunctionalization of metallic implants by calcium phosphate coatings

Article provides a brief summary of state-of-art of surface biofunctionalization on implantable metals by CaP coatings.
Date: May 20, 2019
Creator: Su, Yingchao; Cockerill, Irsalan; Zheng, Yufeng; Tang, Liping; Qin, Yi‐Xian & Zhu, Donghui
System: The UNT Digital Library
Current methods for fabricating 3D cardiac engineered constructs (open access)

Current methods for fabricating 3D cardiac engineered constructs

Article is a review highlighting the various cell types found in cardiac tissues and how they correspond with current advanced fabrication methods for creating cardiac engineered constructs.
Date: May 20, 2022
Creator: Rogozinski, Nicholas; Yanez, Apuleyo; Bhoi, Rahulkumar; Lee, Moo-Yeal & Yang, Huaxiao
System: The UNT Digital Library
Nanocrown electrodes for parallel and robust intracellular recording of cardiomyocytes (open access)

Nanocrown electrodes for parallel and robust intracellular recording of cardiomyocytes

Article develops vertically-aligned nanocrown electrodes that are mechanically robust and achieve > 99% success rates in obtaining intracellular access through electroporation. This technology development provides an advancement towards establishing an iAP screening assay for preclinical evaluation of drug-induced arrhythmogenicity.
Date: April 26, 2022
Creator: Jahed, Zeinab; Yang, Yang; Tsai, Ching-Ting; Foster, Ethan P.; McGuire, Allister F.; Yang, Huaxiao et al.
System: The UNT Digital Library
Hidden Markov model-based activity recognition for toddlers (open access)

Hidden Markov model-based activity recognition for toddlers

Article describes study which sought to evaluate methods for activity recognition for toddlers.
Date: March 5, 2020
Creator: Albert, Mark; Sugianto, Albert; Nickele, Katherine; Zavos, Patricia; Sindu, Pinky; Ali, Munazza et al.
System: The UNT Digital Library
Differential Responses of Transplanted Stem Cells to Diseased Environment Unveiled by a Molecular NIR-II Cell Tracker (open access)

Differential Responses of Transplanted Stem Cells to Diseased Environment Unveiled by a Molecular NIR-II Cell Tracker

This article develops a molecular cell tracker with a strong fluorescence signal in the second near-infrared (NIR-II) window (1,000-1,700 nm) for real-time monitoring of in vivo cell behaviors in both healthy and diseased animal models to address the issue of precisely and quantitatively evaluating the in vivo cell distribution, migration, and engraftment in stem cell therapy.
Date: June 9, 2021
Creator: Chen, Hao; Yang, Huaxiao; Zhang, Chen; Chen, Si; Zhao, Xin; Zhu, Mark et al.
System: The UNT Digital Library
Light-Controlled Cell–Cell Assembly Using Photocaged Oligonucleotides (open access)

Light-Controlled Cell–Cell Assembly Using Photocaged Oligonucleotides

Article asserts that while techniques that allow one to control the arrangement of cells and direct contact between different cell types have been developed that expand upon simple co-culture methods, specific control over heterojunctions that form between cells is not easily accomplished with current methods, such as 3D cell-printing. In this article, DNA-mediated cell interactions are combined with cell-compatible photolithographic approaches to control cell assembly.
Date: May 23, 2023
Creator: Mathis, Katelyn; Kohon, Agia Ibnat; Black, Stephen & Meckes, Brian
System: The UNT Digital Library
Detergent-Based Decellularization for Anisotropic Cardiac-Specific Extracellular Matrix Scaffold Generation (open access)

Detergent-Based Decellularization for Anisotropic Cardiac-Specific Extracellular Matrix Scaffold Generation

Article describes how cell-derived extracellular matrix has become increasingly popular in tissue engineering applications due to its ability to provide tailored signals for desirable cellular responses. The objective of this study was to assess the efficacy of two detergent-based decellularization methods: a combination of ethylenediaminetetraacetic acid and sodium dodecyl sulfate and a combination of sodium deoxycholate and deoxyribonuclease.
Date: November 17, 2023
Creator: Chen, Te-An; Sharma, Dhavan; Jia, Wenkai; Ha, Donggi; Man, Kun; Zhang, Jianhua et al.
System: The UNT Digital Library
Hedgehog signaling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells (open access)

Hedgehog signaling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells

Article states that although KRASG12C inhibitors have shown promising activity in lung adenocarcinomas harboring KRASG12C, acquired resistance to these therapies eventually occurs in most patients. The authors report that the hedgehog signal is induced by KRASG12C inhibitors and mediates KRAS re-expression in cancer cells treated with a KRASG12C inhibitor.
Date: January 16, 2024
Creator: Lee, Chaeyoung; Yi, Jawoon; Park, Jihwan; Ahn, Byungyong; Won, Young-Wook; Jeon, JiHeung et al.
System: The UNT Digital Library
Mesenchymal stem cells aligned and stretched in self-assembling peptide hydrogels (open access)

Mesenchymal stem cells aligned and stretched in self-assembling peptide hydrogels

Article describes how the presented research highlights a novel approach using fmoc-protected peptide hydrogels for the encapsulation and stretching of mesenchymal stem cells. This study utilized a custom mechanical stretching device with a PDMS chamber to stretch human mesenchymal stem cells encapsulated in Fmoc hydrogels.
Date: December 19, 2023
Creator: Fouladgar, Farzaneh; Moslabeh, Forough G. Z.; Kasani, Yashesh V.; Rogozinski, Nick; Torres, Marc; Ecker, Melanie et al.
System: The UNT Digital Library
Multifaceted Shape Memory Polymer Technology for Biomedical Application: Combining Self-Softening and Stretchability Properties (open access)

Multifaceted Shape Memory Polymer Technology for Biomedical Application: Combining Self-Softening and Stretchability Properties

Article describes how thiol-ene polymers are a promising class of biomaterials with a wide range of potential applications, including organs-on-a-chip, microfluidics, drug delivery, and wound healing. This study investigated the incorporation of di-acrylate chain extenders to improve the stretchability and conformability of those flexible thiol-ene polymers.
Date: October 25, 2023
Creator: Chitrakar, Chandani; Torres, Marc Anthony; Rocha-Flores, Pedro Emanuel; Hu, Qichan & Ecker, Melanie
System: The UNT Digital Library
Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model (open access)

Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model

Article describes how recently, natural killer cells emerged as a treatment option for various solid tumors. The effect of activated pancreatic stellate cells on natural killer cell-mediated anticancer efficacy under three-dimensional coculture conditions was investigated.
Date: September 27, 2023
Creator: Kim, Hyun-Ah; Kim, Hyunsoo; Nam, Min-Kyung; Park, Jong Kook; Lee, Moo-Yeal; Chung, Seok et al.
System: The UNT Digital Library
Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries (open access)

Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries

Article describes how skeletal muscle regeneration relies on the tightly temporally regulated lineage progression of muscle stem/progenitor cells (MPCs) from activation to proliferation and finally, differentiation. The authors developed an engineering strategy to tune the therapeutic potential of EVs using nanotopographical cues.
Date: October 5, 2023
Creator: Wang, Kai; Frey, Nolan; Garcia, Andres C.; Man, Kun; Yang, Yong; Gualerzi, Alice et al.
System: The UNT Digital Library
Surface Nanostructures Enhanced Biocompatibility and Osteoinductivity of laser-Additively Manufactured CoCrMo Alloys (open access)

Surface Nanostructures Enhanced Biocompatibility and Osteoinductivity of laser-Additively Manufactured CoCrMo Alloys

Article describes how cobalt–chromium–molybdenum (CoCrMo) alloys are widely used in orthopedic implants due to their excellent corrosion and wear resistance and superior mechanical properties. In this study, the authors prepared CoCrMo alloys with surface nanostructures of various aspect ratios (AR) using laser-directed energy deposition (L-DED) and biocorrosion.
Date: December 6, 2023
Creator: Man, Kun; Mazumder, Sangram; Dahotre, Narendra B. & Yang, Yong
System: The UNT Digital Library