SYNROC is a titanate-based ceramic waste form being developed to immobilize high-level nuclear reactor wastes. SYNROC-D is a unique variation of SYNROC designed to contain high-level defense wastes, particularly those in storage at the Savannah River Plant (SRP). We review recent research and development on SYNROC-D processing options and report on work in progress on various unit operations. The overall immobilization process can be divided into three general parts: (1) slurry preparation (formulation, reactant addition and blending); (2) powder processing (spray drying, calcination/redox control); and (3) mineralization (densification). Powder processing research is directed toward development of a slurry-fed, fluidized-bed calciner based on the ICPP design. Densification research is focused on use of hot isostatic pressing (HIP) or hot uniaxial pressing (HUP). The successful use of both have been demonstrated.