Access
Partner
Collection
Texas Digital Newspaper Program
1,121
UNT Theses and Dissertations
450
The Greensheet
326
Denton County Newspapers Collection
306
UNT Scholarly Works
128
The Monitor
104
Copperas Cove Leader Press
104
Texas Jewish Herald /Jewish Herald /Jewish Herald-Voice
52
Texas Jewish Post
52
Mount Vernon Optic Herald
52
23 More
Degree Department
Digital Projects Unit
108
Libraries
64
College of Music
46
Department of Psychology
37
Department of Biological Sciences
33
Department of Teacher Education and Administration
32
Department of Computer Science and Engineering
21
Department of History
21
Department of Counseling and Higher Education
18
Department of Learning Technologies
17
55 More
Degree Discipline
Degree Level
Country
States
Year
Month
Language
1,812 Matching Results
Results open in a new window/tab.
Homeless Predictors in the Older Adult Population
This secondary research study uses data from two convenience samples of homeless persons in Central Arkansas collected during 2004 and 2011 Point in Time Counts. The prevalence of predictors of homelessness are compared across years, and also compared by age (<50 and > 50) controlling for year of survey. The number of older adults increased significantly between 2004 and 2011 surveys, and reporting serious mental illness and veteran status significantly decreased from 2004 to 2011. Age differences were noted in 2004 with older adults more likely to report serious mental illness in comparison to younger adults. Older adults were also more likely to report veteran status in comparison to younger adults during both the 2004 and 2011 surveys. The predictors of homelessness -- including serious health problems, substance abuse, race, age, and developmental disabilities-- remained fairly consistent from 2004 to 2011 and across "age groups". In addition to Point in Time data, qualitative surveys and interviews of providers were performed for their observations of the older homeless population. Providers indicated their belief that the older homeless population is increasing. Providers suggested possible challenges and reasons for the increase among older adults who are homeless. In central Arkansas, service providers feel …
Date:
May 2013
Creator:
Lewallen, Jina P.
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
A Survey of Four Original Works for Clarinet and Guitar and Their Effect on Compositional Output for the Repertoire
In the last three decades there has been a surge in original compositions for clarinet and guitar resulting in the repertoire virtually doubling in size. However, documentation and research of original works in published sources remains limited and is quickly becoming outdated. This document reviews the current resources and reviews the newer published materials. Early chamber music works for guitar and clarinet typically required the guitar to supply harmonic support to the clarinet's upper voice, which carried the themes. An examination of the earliest works, which date from the early nineteenth century, suggests, in other words, that the two parts were not treated equally, in contrast to modern-day chamber music, in which melodic elements are proportionally balanced between the two instruments. A critical survey and comparison of four significant works from the repertoire reveals a development toward motivic balance, a progression towards melodic equality that continued in subsequent compositions. The four works surveyed are: Heinrich Neumann's Serenata Svizzera Op.29, Ferdinand Rebay's Sonata for Clarinet and Guitar No.2 in A minor, Libby Larsen's Blue Third Piece, and Gernot Wolfgang's Four Miniatures. An extensive compilation of over 300 original published and unpublished works for clarinet and guitar, bass clarinet and guitar, and …
Date:
May 2013
Creator:
Lignitz, Kellie
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
The Character of Environmental Citizenship: Virtue Education for Raising Morally Responsible Individuals
Surely, moral education is not merely intended to result in theoretical knowledge, but instead attempts to change people's behavior. However, when examining and evaluating current trends in moral education, it appears that hitherto moral education has fallen short of its goal to make people better. In this paper, I try to determine what has caused this perceived failure of moral education and conclude that approaches that focus on teaching moral reasoning skills rather than on teaching actual moral content, i.e., values and virtues, are generally ineffective for moral improvement. However, a more traditional form of moral education, namely character education, appears to be a viable alternative to the moral reasoning methods. Since character education can be regarded as the practical application of virtue ethics, I first describe and evaluate virtue ethics and defend it against potential criticisms. I then examine what methods are effective for teaching virtues, and how such methods can potentially be incorporated into the curriculum. Since virtues cannot be taught through theoretical instruction, the acquisition of good habits constitutes the necessary foundation for the establishment of good moral character. Some methods that have been suggested for laying the foundation for virtue are the use of stories, role …
Date:
May 2013
Creator:
Lindemann, Monica A.
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Automated Treetop Detection and Tree Crown Identification Using Discrete-return Lidar Data
Accurate estimates of tree and forest biomass are essential for a wide range of applications. Automated treetop detection and tree crown discrimination using LiDAR data can greatly facilitate forest biomass estimation. Previous work has focused on homogenous or single-species forests, while few studies have focused on mixed forests. In this study, a new method for treetop detection is proposed in which the treetop is the cluster center of selected points rather than the highest point. Based on treetop detection, tree crowns are discriminated through comparison of three-dimensional shape signatures. The methods are first tested using simulated LiDAR point clouds for trees, and then applied to real LiDAR data from the Soquel Demonstration State Forest, California, USA. Results from both simulated and real LiDAR data show that the proposed method has great potential for effective detection of treetops and discrimination of tree crowns.
Date:
May 2013
Creator:
Liu, Haijian
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Optimizing Non-pharmaceutical Interventions Using Multi-coaffiliation Networks
Computational modeling is of fundamental significance in mapping possible disease spread, and designing strategies for its mitigation. Conventional contact networks implement the simulation of interactions as random occurrences, presenting public health bodies with a difficult trade off between a realistic model granularity and robust design of intervention strategies. Recently, researchers have been investigating the use of agent-based models (ABMs) to embrace the complexity of real world interactions. At the same time, theoretical approaches provide epidemiologists with general optimization models in which demographics are intrinsically simplified. The emerging study of affiliation networks and co-affiliation networks provide an alternative to such trade off. Co-affiliation networks maintain the realism innate to ABMs while reducing the complexity of contact networks into distinctively smaller k-partite graphs, were each partition represent a dimension of the social model. This dissertation studies the optimization of intervention strategies for infectious diseases, mainly distributed in school systems. First, concepts of synthetic populations and affiliation networks are extended to propose a modified algorithm for the synthetic reconstruction of populations. Second, the definition of multi-coaffiliation networks is presented as the main social model in which risk is quantified and evaluated, thereby obtaining vulnerability indications for each school in the system. Finally, maximization …
Date:
May 2013
Creator:
Loza, Olivia G.
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Recidivism Among Juvenile Sex Offenders in Texas
Juvenile sex offenders represent a serious and violent group of delinquents. Despite the severity of their crimes, the literature focusing on risk factors that influence recidivism and the types of re-arrest after incarceration is lacking. This research study examined 499 determinately sentenced juvenile sex offenders that were released from the Texas Juvenile Justice Department. This sample was then followed for three years upon their release. This analysis revealed that 51.5 percent were re-arrested for any offense while 45.91 percent were re-arrested for a felony offense. This study identified a number of risk factors relative to JSO recidivism. These factors include having a history of emotional abuse, race being African American, being gang affiliated, having a larger number of previous adjudications, and having higher counts of institutional misconduct infractions. Those JSOs older at intake and release, and those who were incarcerated for longer periods of time were less likely to re-offend upon release. Lastly, this study ends with suggestions for future research as well as policy implications geared toward juvenile sex offenders.
Date:
May 2013
Creator:
Martinez, Crystal G.
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Listening to the Freshman Voice: First-year Self-efficacy and College Expectations Based on High School Types
This quantitative study used Astin's I-E-O theory to explore the relationship between a college freshman's high school background and academic self-efficacy. The Beginning College Survey of Student Engagement was used to measure academic self-efficacy across four types of high schools. Student gender and precollege experiences (dual-credit and communication assertiveness) were used as control. A total of 15,400 first-year students were included in this study. An ANOVA was used to examine the differences between groups, and ordinary least-square analysis was used to study the factors that affect academic self-efficacy. Results showed statistically significant difference in academic self-efficacy between public and private religious high school graduates. Specifically, graduates of public high schools had statistically higher academic self-efficacy than graduates of private religious high schools (p < .001). Additionally, females and participants of dual-credit courses also tended to have higher academic self-efficacy. Finally, analysis revealed that a first-year student's communication confidence is highly correlated to their academic self-efficacy. Results confirm in-coming first-year students perceive higher education engagement differently based on traits attributed to their precollege experiences. Results point to criteria colleges may be able to use in identifying freshmen at risk for low academic self-efficacy and, therefore, for problems in retention and degree …
Date:
May 2013
Creator:
May, Paul B.
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Investigating Postpartum Depression in Southern Rural Egypt and Effects of Sertraline on Fsh and Lh Gene Expression on Fathead Minnows Using Rt-pcr
Postpartum depression (PPD) is a major health problem that affects many women worldwide. In Egypt, PPD is neglected despite the expected high prevalence rate among women during the transition period after the Egyptian revolution. This research investigated the prevalence, risk factors, and interventions of postpartum depression in southern rural Egypt. Interviews were conducted with 57 participants recruited from public and private hospitals. Questionnaires and the Arabic version of the Edinburgh Postnatal Depression Scale were administered. The prevalence of PPD is 73.7%. PPD is associated with low income and age at childbirth. Most participants regarded screening mothers after childbirth for PPD as effective; in comparison to, antidepressants that were regarded by most participants as ineffective. Women in southern rural Egypt prefer high number of pregnancies, so investigating the influence of sertraline, an antidepressant medication, on female hormones becomes important. In this research, fathead minnows were exposed to 3 and 10 ppb sertraline for 7 days. Real-time Polymerase Chain Reaction was used to detect the change in gene expression of the Follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Results showed that a down regulation at the 10 ppb was evident on the LH and to a lesser extent on FSH. Our results …
Date:
May 2013
Creator:
Mohamed, Hagar Abdo
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Examination of the Relationship Between Glucuronic Acid and Vascular Damage in Rats
The goal of this experiment was to examine the role of glucuronic acid in the development of vascular damage in the kidneys and retinas of diabetic individuals. Glucuronic acid was provided to rats in their water at various concentrations in order to increase plasma levels of the compound. Kidneys and retinas were excised and compared to control specimens using microscopy to determine the effect of elevated blood glucuronic acid levels on the occurrence of microaneurysms in renal capillary networks. No differences were seen between the treatment and control groups. Further study needs to be conducted to determine a more suitable time frame for this experiment.
Date:
May 2013
Creator:
Moore, Ryan
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Don Gillis's Symphony No 5½: Music for the People
Don Gillis wrote Symphony No. 5½ (1947) in order to reconcile the American public with modern art music. By synthesizing jazz (as well as other American folk idioms), singable melodies, and humor, and then couching them into symphonic language, Gillis produced a work that lay listeners could process and enjoy. The piece was an immediate success and was played by orchestras across the globe, but it did not retain this popularity and it eventually faded from relevancy. This study focuses on elements that contributed to the initial efficacy and ultimate decline of the work. Due to its pervasive popular influences, Symphony No. 5½ is a crystallized representation of time in which it was written, and it soon became dated. Don Gillis did not harbor the idea that Symphony No. 5½ would grant him great wealth or musical immortality; he had a more pragmatic goal in mind. He used every musical element at his disposal to write a symphonic work that would communicate directly with the American people via a musical language they would understand. He was successful in this regard, but the dialogue ended soon after mid-century.
Date:
May 2013
Creator:
Morrison, Sean
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Interspecimen Study of Bone to Relate Macromechanical, Nanomechanical and Compositional Changes Across the Femoral Cortex of Bone
Mechanics of bone is widely studied and researched, mainly for the study of fracture. This has been done mostly on a macro scale. In this work hierarchical nature of bone has been explored to investigate bone mechanics in more detail. Flexural test were done to classify the bones according to their strength and deflection. Raman spectroscopy analysis was done to map the mineralization, collagen crosslinking changes across the thickness of the bone. Nanoindentation was done to map indentation hardness and indentation modulus across femoral cortex of the bone. The results indicate that the composition of the bone changes across the thickness of the femoral cortex. The hypothesis is confirmed as increase in mineralization, carbonate to phosphate ratio and collagen crosslinking shows the effect as increased indentation hardness and modulus and decreased deflection.
Date:
May 2013
Creator:
Nar, Mangesh
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Using a Multimodal Sensing Approach to Characterize Human Responses to Affective and Deceptive States
Different ways to measure human affective and deceptive reactions to stimulus have been developed. One method is a multimodal approach using web camera, thermal imaging camera and physiological sensors data to extract different features in the human face (verbal and non-verbal behavior) such as breathing rate, heart rate, face temperature, skin conductance, eye tracking, language analysis and facial expressions among others. Human subjects from different ages and ethnicity were exposed to two different experiments were they watched videos (affection recognition) and others answered an interview session (deception recognition). With the data collected from videos (thermal and visual), different regions of interest (ROI) of the face were selected as well as the whole picture. The ROI were determined based on the most sensitive parts of the face where larger changes of temperature or other physiological features are recorded. It was also analyzed the language (written and spoken) in order to obtain the verbal modalities. The data has been compared among the subjects to determine whether the deceptive and affective reactions of a person can be predicted using multimodal approach. From the multiple data obtained, a characterization of reactions is proposed when subjects are exposed to different stimulus, positive or negative, as …
Date:
May 2013
Creator:
Narvaez-Valle, Alexis
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Convergent Validity of Variables Residualized By a Single Covariate: the Role of Correlated Error in Populations and Samples
This study examined the bias and precision of four residualized variable validity estimates (C0, C1, C2, C3) across a number of study conditions. Validity estimates that considered measurement error, correlations among error scores, and correlations between error scores and true scores (C3) performed the best, yielding no estimates that were practically significantly different than their respective population parameters, across study conditions. Validity estimates that considered measurement error and correlations among error scores (C2) did a good job in yielding unbiased, valid, and precise results. Only in a select number of study conditions were C2 estimates unable to be computed or produced results that had sufficient variance to affect interpretation of results. Validity estimates based on observed scores (C0) fared well in producing valid, precise, and unbiased results. Validity estimates based on observed scores that were only corrected for measurement error (C1) performed the worst. Not only did they not reliably produce estimates even when the level of modeled correlated error was low, C1 produced values higher than the theoretical limit of 1.0 across a number of study conditions. Estimates based on C1 also produced the greatest number of conditions that were practically significantly different than their population parameters.
Date:
May 2013
Creator:
Nimon, Kim
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Down, Set, Like? A Study of Social Networking and Sports Fandom
Sports in the 21st century have become popular across multiple industries, and a major boon to a television industry dealing with increasing audience fragmentation. So an understanding of fans' behavior is important to all parties. This study, an online survey consisting of 242 responses, examined fandom and its relationship with time spent using social networking sites and found no statistical correlation. Six uses and gratification factors obtained: human connection, network content, distraction/amusement, social integration, social surveillance, and active entertainment. The low comparative saliency of the social integration factor suggests that perhaps fandom is distinct from other ways of identifying with similarly-minded individuals (e.g. political and/or religious affiliation), or that perhaps fandom as a factor is less than sufficient to explain how/why sports fans use social networking sites.
Date:
May 2013
Creator:
Otteson, Gabe
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Warrior Women in Early Modern Literature
Fantasies about warrior women circulated in many forms of writing in early modern England: travel narratives such as Sir Walter Ralegh's The Discoverie of Guiana (1595) portray Amazon encounters in the New World; poems like Edmund Spenser's The Faerie Queene (1596) depict women's skill with a spear; and the plays of Shakespeare, John Fletcher, and others stage the adventurous feats of women on the battlefield. In this dissertation, I analyze the social anxieties that emerge when warrior women threaten gender hierarchies in the patriarchal society of early modern England. The battlefield has traditionally been a site for men to prove their masculinity against other men, so when male characters find themselves submitting to a sword-wielding woman, they are forced to reimagine their own masculine identities as they become the objects acted upon by women. In their experience of subjectivity, these literary warrior women often allude to the historical Queen Elizabeth I, whose reign destabilized ideas about gender and power in the period. Negative evaluations of warrior women often indicate anxiety about Elizabeth as an Amazon-like queen. Thus, portrayals of warrior women often end with a celebration of patriarchal dominance once the male characters have successfully contained the threat of the …
Date:
May 2013
Creator:
Oxendine, Jessica Grace
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Accomplished Teachers' Instructional Decisions About Shakespeare
Teachers' decisions are a powerful influence on student learning and it is important to fully document accomplished teachers' instructional decisions, as well as to investigate possible influences on those decisions. Shakespearean dramas are central to high school curricula across the U.S. and pose particular instructional challenges, therefore teachers' decisions about teaching these texts are of particular interest. There is limited empirical research, however, about these instructional decisions. Thus, the purpose of this study was to describe how four accomplished high school English teachers working on a single campus make instructional decisions about teaching a Shakespearean play. Specifically, research questions addressed teachers' decisions regarding the teaching of a Shakespearean play and various influences on those decisions (self-reports and inferences from the data). Case study methodology was used, including an inductive analysis of individual teacher interviews, classroom observations, focus group, instructional artifacts, and researcher's journal. The findings revealed that instructional activities described by these teachers addressed support for meaning-making during four stages of reading instruction: (a) before, during, and after; (b) before; (c) during; and (d) after. Comparison of these cases suggests that, although each teacher brings personal preferences and unique background knowledge to her instructional decisions, all make decisions to promote …
Date:
May 2013
Creator:
Parris, Sheri Rene’
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Data Transmission in Quantized Consensus
In the world of networked system, average consensus is an important dimension of co-ordinate control and cooperation. Since the communication medium is digital, real value cannot be transmitted and we need to perform quantization before data transmission. But for the quantization, error is introduced in exact value and initial average is lost. Based on this limitation, my 16 bit quantization method (sending MSB in 1-4 cycle and MSB+LSB in 5th cycle) reduces error significantly and preserves initial average. Besides, it works on all types of graphs (star, complete, ring, random geometric graph). My other algorithm, distributing averaging algorithm (PQDA) with probabilistic quantization also works on random geometric graph, star, ring and slow co-herency graph. It shows significant reduced error and attain strict consensus.
Date:
May 2013
Creator:
Parvez, Imtiaz
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
A Study of Performance and Effort Expectancy Factors Among Generational and Gender Groups to Predict Enterprise Social Software Technology Adoption
Social software technology has gained considerable popularity over the last decade and has had a great impact on hundreds of millions of people across the globe. Businesses have also expressed their interest in leveraging its use in business contexts. As a result, software vendors and business consumers have invested billions of dollars to use social software to improve business and employee productivity. The purpose of this study was to provide insights to business leaders and decision makers as they shaped their enterprise social software (ESS) delivery plans. A vast body of information exists on the benefits of ESS and its technical implementation, but little empirical research is available on employees' perceptions of ESS expectancy factors (i.e. usefulness and ease of use). This study focused on IT managers' perceptions of ESS expectancy factors to understand their behavioral intent to adopt ESS technology. Additional research was performed to uncover relationships and differences between IT Managers' adoption intentions and employee age, gender, and generational groups. Survey results were analyzed using a correlation research design and demonstrated significant relationships were found between IT managers' expectancy factors and their behavioral intent to adopt ESS technology. Differences were also demonstrated between IT managers' age, gender, and …
Date:
May 2013
Creator:
Patel, Sunil S.
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Traveling Wave Solutions of the Porous Medium Equation
We prove the existence of a one-parameter family of solutions of the porous medium equation, a nonlinear heat equation. In our work, with space dimension 3, the interface is a half line whose end point advances at constant speed. We prove, by using maximum principle, that the solutions are stable under a suitable class of perturbations. We discuss the relevance of our solutions, when restricted to two dimensions, to gravity driven flows of thin films. Here we extend the results of J. Iaia and S. Betelu in the paper "Solutions of the porous medium equation with degenerate interfaces" to a higher dimension.
Date:
May 2013
Creator:
Paudel, Laxmi P.
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Corrosion Protection of Low Carbon Steel By Cation Substituted Magnetite
Surfaces of low carbon steel sheet were modified by exposure to highly caustic aqueous solutions containing either chromium or aluminum cations. Corrosion resistances of such surfaces were compared with that of steel surfaces exposed to plain caustic aqueous solution. In all cases a highly uniform, black coating having a spinel structure similar to magnetite (Fe3O4) was obtained. The coated steel surfaces were characterized using X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and Fourier transform infrared spectrophotometry (FTIR). Polarization resistances (Rp) of modified steel surfaces were measured and compared with that of bare steel surfaces. Results indicate that chromium (Fe2+ Fe3+x Cr3+1-x) or aluminum (Fe2+ Fe3+x Al3+1-x) substituted spinel phases formed on steel surfaces showed higher Rp values compared to only magnetite (Fe2+ 2Fe3+O4) phase formed in the absence of either chromium or aluminum cations. Average Rp values for steel surfaces with chromium containing spinel phase were much higher (21.8 k?) as compared to 1.7 k? for bare steel surfaces. Steel surfaces with aluminum containing spinel phase and steels with plain magnetite coated samples showed average Rp values of 3.3 k? and 2.5 k? respectively. XPS and EDS analysis confirmed presence of cations of chromium and …
Date:
May 2013
Creator:
Phadnis, Ameya
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Design of a Dual Band Gan Pa Utilizing Dual Band Impedance Transformers
This thesis discusses the design, fabrication, and testing of a high efficiency, dual band radio frequency power amplifier. While it is difficult to demonstrate an exact mode of operation for power amplifiers at radio frequencies, based on the characteristics of the transistor itself, the argument can be made that our high efficiency performance is due to an approximation to class E operation. The PA is designed around a CGH40025 transistor manufactured by Cree, Inc, which has developed a very useful nonlinear model of its transistor, which allows use of software load/source pull methods to determine optimum impedances to be presented to the gate and drain (hereafter referred to as source and load) of the transistor at each band of operation. A recent work on dual-band impedance matching is then used to design distributed element networks in order to present conjugate matches of these impedances to the transistor. This is followed by a careful layout, after which the PA is then fabricated on a low-impedance substrate using a LPKF Protomat S63 rapid prototyping machine. Measurements of gain and drain current provide values for power-added-efficiency. Simulated gains were 21 and 18 dB at 800 MHz and 1.85 GHz, respectively, with PAE around …
Date:
May 2013
Creator:
Poe, David R.
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Supply Chain Network Planning for Humanitarian Operations During Seasonal Disasters
To prevent loss of lives during seasonal disasters, relief agencies distribute critical supplies and provide lifesaving services to the affected populations. Despite agencies' efforts, frequently occuring disasters increase the cost of relief operations. The purpose of our study is to minimize the cost of relief operations, considering that such disasters cause random demand. To achieve this, we have formulated a series of models, which are distinct from the current studies in three ways. First, to the best of our knowledge, we are the first ones to capture both perishable and durable products together. Second, we have aggregated multiple products in a different way than current studies do. This unique aggregation requires less data than that of other types of aggregation. Finally, our models are compatible with the practical data generated by FEMA. Our models offer insights on the impacts of various parameters on optimum cost and order size. The analyses of correlation of demand and quality of information offer interesting insights; for instance, under certain cases, the quality of information does not influence cost. Our study has considered both risk averse and risk neutral approaches and provided insights. The insights obtained from our models are expected to help agencies reduce …
Date:
May 2013
Creator:
Ponnaiyan, Subramaniam
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Expression of G-protein Coupled Receptors in Young and Mature Thrombocytes and Knockdown of Gpr18 in Zebrafish
In this study, a novel method based on biotinylated antibodies and streptavidin coated magnetic beads was used to separate the thrombocyte subpopulations from zebrafish whole blood. DiI-C18, a lipophilic dye, labels only young thrombocytes when used at low concentrations. Commercially available biotinylated anti-Cy3 antibody was used to label the chromophore of DiI-C18 on the young thrombocytes and streptavidin coated magnetic beads were added subsequently, to separate young thrombocytes. The remaining blood cells were probed with custom-made biotinylated anti-GPIIb antibody and streptavidin magnetic beads to separate them from other cells. Further, thrombocytes are equivalents of mammalian platelets. Platelets play a crucial role in thrombus formation. The G-protein coupled receptors (GPCRs) present on the platelet surface are involved during platelet activation and aggregation processes. So, thrombocytes were studied for the presence of GPCRs. The GPCR mRNA transcripts expressed in the young and mature thrombocytes were subjected to densitometry analysis and pixel intensities of the bands were compared using one way ANOVA. This analysis did not show significant differences between the young and mature GPCR mRNA transcripts but identified a novel GPCR, GPR18 that was not reported in platelets earlier. To study the function of this GPCR, it was knocked down using GPR18 …
Date:
May 2013
Creator:
Potbhare, Vrinda Nikhil
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Muerte Y Soledad En La Poesía De Manuel Altolaguirre Ante El Exilio
This study focuses on the Spanish poet of the Generation of '27 Manuel Altolaguirre. The purpose of this thesis is to show how the poetry of Manuel Altolaguirre evolves in relation to specific issues. Specifically, I study the changes in his work in regard to the themes of death and solitude, resulting from exile in 1939, to be enriched by new experiences, many of them dramatic, taking more personal ways, while offering them a more profound and complex and even in regard to the subject of the poet's death comes to contemplate a more positive way. The thesis is divided into five chapters. Following the introduction, the second chapter focuses on Altolaguirre's biography and the Generation in 1927 while the third focuses and analyzes his poetry before his exile in 1939. The fourth chapter examines his poetry after exile until his death in 1959, while the fifth and last chapter concludes this study.
Date:
May 2013
Creator:
Mandujano, Olga Lidia
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library