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Role of human- and animal-sperm studies in the evaluation of male reproductive hazards (open access)

Role of human- and animal-sperm studies in the evaluation of male reproductive hazards

Human sperm tests provide a direct means of assessing chemically induced spermatogenic dysfunction in man. Available tests include sperm count, motility, morphology (seminal cytology), and Y-body analyses. Over 70 different human exposures have been monitored in various groups of exposed men. The majority of exposures studied showed a significant change from control in one or more sperm tests. When carefully controlled, the sperm morphology test is statistically the most sensitive of these human sperm tests. Several sperm tests have been developed in nonhuman mammals for the study of chemical spermatotoxins. The sperm morphology test in mice has been the most widely used. Results with this test seem to be related to germ-cell mutagenicity. In general, animal sperm tests should play an important role in the identification and assessment of potential human reproductive hazards. Exposure to spermatotoxins may lead to infertility, and more importantly, to heritable genetic damage. While there are considerable animal and human data suggesting that sperm tests may be used to detect agents causing infertility, the extent to which these tests detect heritable genetic damage remains unclear. (ERB)
Date: April 7, 1982
Creator: Wyrobek, A.J.; Gordon, L. & Watchmaker, G.
System: The UNT Digital Library
Pulse-power circuit diagnostics for the Nova laser (open access)

Pulse-power circuit diagnostics for the Nova laser

The Nova laser will have a large pulse power system for driving laser amplifiers, incorporating approximately 1600 flashlamp circuits. An automated system has been designed for diagnosing the condition of these flashlamp circuits. It records digitized circuit current waveforms and detects current excursions above a given threshold. In addition, it is able to fire flashlamps at a low energy to ascertain the health of the system. Data from this system can be ploted for inspection by the operator, analyzed by the computer system and archived for future reference.
Date: June 7, 1982
Creator: Christie, D. J.; Dallum, G. E.; Gritton, D. G.; Merritt, B. T.; Whitham, K. & Berkbigler, L. W.
System: The UNT Digital Library
Radiative effects of a CO/sub 2/ increase: results of a model comparison (open access)

Radiative effects of a CO/sub 2/ increase: results of a model comparison

A comparison of infrared radiative transfer models is announced. The initial phase is underway, with other phases scheduled through 1984. The results of the ir model comparison will be included in the state-of-the-art report on climate modeling. Although the time scale for completion of the comparison is a few years, significant preliminary results have already been obtained. (PSB)
Date: October 7, 1982
Creator: Luther, F.M.
System: The UNT Digital Library
Producing thermochemical hydrogen with the tandem-mirror reactor (open access)

Producing thermochemical hydrogen with the tandem-mirror reactor

Fusion power holds the promise to supply not only electricity but also fuels to meet the balance of our energy needs. A new integrated power and breeding blanket design is described for tandem mirror reactors. The blanket incorporates features that make it suitable for synthetic fuel production. In particular, it is matched to the thermal and electrical power requirements of the General Atomic water-splitting process for production of hydrogen. Some improvements to the high temperature chemical process steps are described. These improvements are expected to allow production of hydrogen at about $13/GJ wholesale, including financing costs, capital amortization, and profit.
Date: May 7, 1982
Creator: Werner, R. W. & Hickman, R. G.
System: The UNT Digital Library