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Interim Report on Multiple Sequence Alignments and TaqMan Signature Mapping to Phylogenetic Trees
The goal of this project is to develop forensic genotyping assays for select agent viruses, addressing a significant capability gap for the viral bioforensics and law enforcement community. We used a multipronged approach combining bioinformatics analysis, PCR-enriched samples, microarrays and TaqMan assays to develop high resolution and cost effective genotyping methods for strain level forensic discrimination of viruses. We have leveraged substantial experience and efficiency gained through year 1 on software development, SNP discovery, TaqMan signature design and phylogenetic signature mapping to scale up the development of forensics signatures in year 2. In this report, we have summarized the Taqman signature development for South American hemorrhagic fever viruses, tick-borne encephalitis viruses and henipaviruses, Old World Arenaviruses, filoviruses, Crimean-Congo hemorrhagic fever virus, Rift Valley fever virus and Japanese encephalitis virus.
Date:
March 27, 2012
Creator:
Gardner, S & Jaing, C
Object Type:
Report
System:
The UNT Digital Library
Interim report on updated microarray probes for the LLNL Burkholderia pseudomallei SNP array
The overall goal of this project is to forensically characterize 100 unknown Burkholderia isolates in the US-Australia collaboration. We will identify genome-wide single nucleotide polymorphisms (SNPs) from B. pseudomallei and near neighbor species including B. mallei, B. thailandensis and B. oklahomensis. We will design microarray probes to detect these SNP markers and analyze 100 Burkholderia genomic DNAs extracted from environmental, clinical and near neighbor isolates from Australian collaborators on the Burkholderia SNP microarray. We will analyze the microarray genotyping results to characterize the genetic diversity of these new isolates and triage the samples for whole genome sequencing. In this interim report, we described the SNP analysis and the microarray probe design for the Burkholderia SNP microarray.
Date:
March 27, 2012
Creator:
Gardner, S & Jaing, C
Object Type:
Report
System:
The UNT Digital Library
Science and Technology Review April/May 2013
None
Date:
March 1, 2013
Creator:
Simon, A J
Object Type:
Report
System:
The UNT Digital Library
Limit of detection of Bacillus anthracis in complex soil and air samples using next-generation sequencing
None
Date:
March 15, 2012
Creator:
Be, Nicholas A.; Thissen, James B.; Gardner, Shea; McLoughlin, Kevin; Fofanov, Viacheslav; Koshinsky, Heather et al.
Object Type:
Article
System:
The UNT Digital Library
Science and Technology Review April/May 2011
At Lawrence Livermore National Laboratory, the focus is on science and technology research to ensure the nation's security. That expertise is also applied to solve other important national problems in energy, bioscience, and the environment. Science & Technology Review is published eight time a year to communicate, to a broad audience, the Laboratory's scientific and technological accomplishments in fulfilling its primary missions. The publication's goal is to help readers understand these accomplishments and appreciate their value to the individual citizen, the nation, and the world. In this issue for April/May 2011, the features are 'Dealing with the Nonlinear Battlefield' and 'From Video to Knowledge.' Research highlights are 'Kinetic Models Predict Biofuel Efficiency,' Going Deep with MEGa-Rays' and 'Energy on Demand.'
Date:
March 3, 2011
Creator:
Nikolic, R J
Object Type:
Report
System:
The UNT Digital Library
Laboratory Directed Research and Development FY2010 Annual Report
A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has at its core a primary national security mission - to ensure the safety, security, and reliability of the nation's nuclear weapons stockpile without nuclear testing, and to prevent and counter the spread and use of weapons of mass destruction: nuclear, chemical, and biological. The Laboratory uses the scientific and engineering expertise and facilities developed for its primary mission to pursue advanced technologies to meet other important national security needs - homeland defense, military operations, and missile defense, for example - that evolve in response to emerging threats. For broader national needs, LLNL executes programs in energy security, climate change and long-term energy needs, environmental assessment and management, bioscience and technology to improve human health, and for breakthroughs in fundamental science and technology. With this multidisciplinary expertise, the Laboratory serves as a science and technology resource to the U.S. government and as a partner with industry and academia. This annual report discusses the following topics: (1) Advanced Sensors and Instrumentation; (2) Biological Sciences; (3) Chemistry; (4) Earth and Space Sciences; (5) Energy Supply and Use; (6) Engineering and Manufacturing Processes; (7) Materials Science and Technology; Mathematics and Computing Science; (8) Nuclear …
Date:
March 22, 2011
Creator:
Jackson, K J
Object Type:
Report
System:
The UNT Digital Library
RHIC Polarized proton operation
The Relativistic Heavy Ion Collider (RHIC) operation as the polarized proton collider presents unique challenges since both luminosity(L) and spin polarization(P) are important. With longitudinally polarized beams at the experiments, the figure of merit is LP{sup 4}. A lot of upgrades and modifications have been made since last polarized proton operation. A 9 MHz rf system is installed to improve longitudinal match at injection and to increase luminosity. The beam dump was upgraded to increase bunch intensity. A vertical survey of RHIC was performed before the run to get better magnet alignment. The orbit control is also improved this year. Additional efforts are put in to improve source polarization and AGS polarization transfer efficiency. To preserve polarization on the ramp, a new working point is chosen such that the vertical tune is near a third order resonance. The overview of the changes and the operation results are presented in this paper. Siberian snakes are essential tools to preserve polarization when accelerating polarized beams to higher energy. At the same time, the higher order resonances still can cause polarization loss. As seen in RHIC, the betatron tune has to be carefully set and maintained on the ramp and during the store …
Date:
March 28, 2011
Creator:
Huang, H.; Ahrens, L.; Alekseev, I. G.; Aschenauer, E.; Atoian, G.; Bai, M. et al.
Object Type:
Article
System:
The UNT Digital Library
Viscosity of multi-component molten nitrate salts : liquidus to 200 degrees C.
The viscosity of molten salts comprising ternary and quaternary mixtures of the nitrates of sodium, potassium, lithium and calcium was determined experimentally. Viscosity was measured over the temperature range from near the relatively low liquidus temperatures of he individual mixtures to 200C. Molten salt mixtures that do not contain calcium nitrate exhibited relatively low viscosity and an Arrhenius temperature dependence. Molten salt mixtures that contained calcium nitrate were relatively more viscous and viscosity increased as the roportion of calcium nitrate increased. The temperature dependence of viscosity of molten salts containing calcium nitrate displayed curvature, rather than linearity, when plotted in Arrhenius format. Viscosity data for these mixtures were correlated by the Vogel-Fulcher- ammann-Hesse equation.
Date:
March 1, 2010
Creator:
Bradshaw, Robert W.
Object Type:
Report
System:
The UNT Digital Library
Gainesville Daily Register (Gainesville, Tex.), Vol. 127, No. 135, Ed. 1 Wednesday, March 8, 2017
Daily newspaper from Gainesville, Texas that includes local, state, and national news along with advertising.
Date:
March 8, 2017
Creator:
Armstrong, Mark J.
Object Type:
Newspaper
System:
The Portal to Texas History
Gainesville Daily Register (Gainesville, Tex.), Vol. 127, No. 141, Ed. 1 Friday, March 17, 2017
Daily newspaper from Gainesville, Texas that includes local, state, and national news along with advertising.
Date:
March 17, 2017
Creator:
Armstrong, Mark J.
Object Type:
Newspaper
System:
The Portal to Texas History
Gainesville Daily Register (Gainesville, Tex.), Vol. 128, No. 141, Ed. 1 Saturday, March 17, 2018
Daily newspaper from Gainesville, Texas that includes local, state, and national news along with advertising.
Date:
March 17, 2018
Creator:
Armstrong, Mark J.
Object Type:
Newspaper
System:
The Portal to Texas History
Still the Arena of Civil War: Violence and Turmoil in Reconstruction Texas, 1865/1874
Access:
Use of this item is restricted to the UNT Community
Following the Civil War, the United States was fully engaged in a bloody conflict with ex-Confederates, conservative Democrats, and members of organized terrorist groups, such as the Ku Klux Klan, for control of the southern states. Texas became one of the earliest battleground states in the War of Reconstruction. Throughout this era, white Texans claimed that Radical Republicans in Congress were attempting to dominate their state through “Negro-Carpetbag-Scalawag rule.” In response to these perceived threats, whites initiated a violent guerilla war that was designed to limit support for the Republican Party. They targeted loyal Unionists throughout the South, especially African Americans who represented the largest block of Republican voters in the region. Was the Reconstruction era in the Lone Star State simply a continuation of the Civil War? Evidence presented by sixteen contributors in this new anthology, edited by Kenneth W. Howell, argues that this indeed was the case. Topics include the role of the Freedmen’s Bureau and the occupying army, focusing on both sides of the violence. Several contributors analyze the origins of the Ku Klux Klan and its operations in Texas, how the Texas State Police attempted to quell the violence, and Tejano adjustment to Reconstruction. Other chapters …
Date:
March 15, 2012
Creator:
Howell, Kenneth W.
Object Type:
Book
System:
The UNT Digital Library
Novel Perspectives for Hadron Physics
I discuss several novel and unexpected aspects of quantum chromodynamics. These include: (a) the nonperturbative origin of intrinsic strange, charm and bottom quarks in the nucleon at large x; the breakdown of pQCD factorization theorems due to the lensing effects of initial- and final-state interactions; (b) important corrections to pQCD scaling for inclusive reactions due to processes in which hadrons are created at high transverse momentum directly in the hard processes and their relation to the baryon anomaly in high-centrality heavy-ion collisions; and (c) the nonuniversality of quark distributions in nuclei. I also discuss some novel theoretical perspectives in QCD: (a) light-front holography - a relativistic color-confining first approximation to QCD based on the AdS/CFT correspondence principle; (b) the principle of maximum conformality - a method which determines the renormalization scale at finite order in perturbation theory yielding scheme independent results; (c) the replacement of quark and gluon vacuum condensates by 'in-hadron condensates' and how this helps to resolve the conflict between QCD vacuum and the cosmological constant.
Date:
March 9, 2012
Creator:
Brodsky, Stanley J.
Object Type:
Article
System:
The UNT Digital Library
Expedited Removal Authority for VA Senior Executives (38 U.S.C. § 713): Selected Legal Issues
This report discusses selected legal issues relating to the authority for summary removal of individuals in senior executive positions at the Department of Veterans Affairs.
Date:
March 4, 2016
Creator:
Nicola, Thomas J.
Object Type:
Report
System:
The UNT Digital Library
Gainesville Daily Register (Gainesville, Tex.), Vol. 127, No. 140, Ed. 1 Thursday, March 16, 2017
Daily newspaper from Gainesville, Texas that includes local, state, and national news along with advertising.
Date:
March 16, 2017
Creator:
Armstrong, Mark J.
Object Type:
Newspaper
System:
The Portal to Texas History
Raza Rising: Chicanos in North Texas
Access:
Use of this item is restricted to the UNT Community
Book about Chicano and Latino experiences in North Texas, based on the author's personal history, newspaper articles, community input, and other sources. Chapters address education, culture, politics, heritage, and related topics.
Date:
March 2016
Creator:
Gonzales, Richard J.
Object Type:
Book
System:
The UNT Digital Library
Evaluation of Visual Impact on Cultural Resources/Historic Properties: North Atlantic, Mid-Atlantic, South Atlantic, and Florida Straits, Volume 2: Appendices
A list of appendices for reference to the "Evaluation of Visual Impact on Cultural Resources/Historic Properties: North Atlantic, Mid-Atlantic, South Atlantic, and Florida Straits" study.
Date:
March 2012
Creator:
Klein, Joel I.; Harris, Matthew D.; Tankersley, W. Matthew; Meyer, Richard; Smith, Greg C. & Chadwick, William J.
Object Type:
Text
System:
The UNT Digital Library
TNR and conservation on a university campus: a political ecological perspective
Article discussing TNR and conservation on a university campus and a political ecological perspective.
Date:
September 25, 2013
Creator:
Dombrosky, Jonathan & Wolverton, Steven J.
Object Type:
Article
System:
The UNT Digital Library
Final Report for the ZERT Project: Basic Science of Retention Issues, Risk Assessment & Measurement, Monitoring and Verification for Geologic Sequestration
ZERT has made major contributions to five main areas of sequestration science: improvement of computational tools; measurement and monitoring techniques to verify storage and track migration of CO{sub 2}; development of a comprehensive performance and risk assessment framework; fundamental geophysical, geochemical and hydrological investigations of CO{sub 2} storage; and investigate innovative, bio-based mitigation strategies.
Date:
March 31, 2011
Creator:
Spangler, Lee; Cunningham, Alfred; Lageson, David; Melick, Jesse; Gardner, Mike; Dobeck, Laura et al.
Object Type:
Report
System:
The UNT Digital Library
Status of head-on beam-beam compensation in RHIC
N/A
Date:
March 18, 2013
Creator:
Fischer, W.; Altinbas, Z.; Anerella, M.; Blaskiewicz, M.; Bruno, D.; Costanzo, M. et al.
Object Type:
Article
System:
The UNT Digital Library
Justice Antonin Scalia: His Jurisprudence and His Impact on the Court
This report discusses Justice Scalia's jurisprudence on key areas of law, as well as how that jurisprudence could be seen to have influenced the Court's approach to these subject matters.
Date:
March 18, 2016
Creator:
Manuel, Kate M.; Murrill, Brandon J. & Nolan, Andrew
Object Type:
Report
System:
The UNT Digital Library
Messiah College Biodiesel Fuel Generation Project Final Technical Report
Many obvious and significant concerns arise when considering the concept of small-scale biodiesel production. Does the fuel produced meet the stringent requirements set by the commercial biodiesel industry? Is the process safe? How are small-scale producers collecting and transporting waste vegetable oil? How is waste from the biodiesel production process handled by small-scale producers? These concerns and many others were the focus of the research preformed in the Messiah College Biodiesel Fuel Generation project over the last three years. This project was a unique research program in which undergraduate engineering students at Messiah College set out to research the feasibility of small-biodiesel production for application on a campus of approximately 3000 students. This Department of Energy (DOE) funded research program developed out of almost a decade of small-scale biodiesel research and development work performed by students at Messiah College. Over the course of the last three years the research team focused on four key areas related to small-scale biodiesel production: Quality Testing and Assurance, Process and Processor Research, Process and Processor Development, and Community Education. The objectives for the Messiah College Biodiesel Fuel Generation Project included the following: 1. Preparing a laboratory facility for the development and optimization of processors …
Date:
March 30, 2012
Creator:
Zummo, Michael M.; Munson, J.; Derr, A.; Zemple, T.; Bray, S.; Studer, B. et al.
Object Type:
Report
System:
The UNT Digital Library
Development of field performance evaluation tools and program for pavement marking materials: technical report
Report on a project is to investigate field evaluation plans and procedures, and develop field performance-based evaluation procedures for pavement marking materials.
Date:
March 2011
Creator:
Zhang, Yunlong; Ge, Hancheng; Pike, Adam & Carlson, Paul J.
Object Type:
Report
System:
The Portal to Texas History
COYOTE : a finite element computer program for nonlinear heat conduction problems. Part I, theoretical background.
The need for the engineering analysis of systems in which the transport of thermal energy occurs primarily through a conduction process is a common situation. For all but the simplest geometries and boundary conditions, analytic solutions to heat conduction problems are unavailable, thus forcing the analyst to call upon some type of approximate numerical procedure. A wide variety of numerical packages currently exist for such applications, ranging in sophistication from the large, general purpose, commercial codes, such as COMSOL, COSMOSWorks, ABAQUS and TSS to codes written by individuals for specific problem applications. The original purpose for developing the finite element code described here, COYOTE, was to bridge the gap between the complex commercial codes and the more simplistic, individual application programs. COYOTE was designed to treat most of the standard conduction problems of interest with a user-oriented input structure and format that was easily learned and remembered. Because of its architecture, the code has also proved useful for research in numerical algorithms and development of thermal analysis capabilities. This general philosophy has been retained in the current version of the program, COYOTE, Version 5.0, though the capabilities of the code have been significantly expanded. A major change in the code …
Date:
March 1, 2010
Creator:
Glass, Micheal W.; Hogan, Roy E., Jr. & Gartling, David K.
Object Type:
Report
System:
The UNT Digital Library